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Scientists now closer to produce drugs to fix disease-causing mutations, spare healthy genes

Inherited diseases such as cystic fibrosis can be caused by genetic "nonsense mutations" that disrupt the way human cells make proteins. David Bedwell, Ph.D., a professor in the University of Alabama at Birmingham Department of Microbiology, says scientists are now closer to producing drugs that will fix this disruption and drastically improve treatment of genetic disease.

27 Apr 2010

Slitrk5 gene linked to development of OCD-like behaviors

Researchers at the Ansary Stem Cell Institute and the Department of Psychiatry at Weill Cornell Medical College discovered that mice missing a single gene developed repetitive obsessive-compulsive-like behaviors. The genetically altered mice, which behaved much like people with a certain type of obsessive-compulsive disorder (OCD), could help scientists design new therapies for this debilitating condition.

27 Apr 2010

Study links progression of lethal type of brain tumor with reduced expression of immune system genes

A new study links progression of a lethal type of brain tumor with reduced expression of more than 600 immune system genes, suggesting how complex the immune response is to the cancer and the resulting difficulty in targeting specific immune system proteins for treatment.

27 Apr 2010

CocE exhibits potential for clinical treatment of cocaine toxicity

Cocaine toxicity due to drug overdose results in more than half a million emergency room visits annually. Despite these alarming statistics, there is no Food and Drug Administration-approved pharmacotherapy specifically designed to treat cocaine toxicity. Emergency medical personnel are limited to treating only the immediate life-threatening symptoms of patients, while toxic levels of cocaine and its metabolic break-down products persist and continue to damage the cardiovascular system, liver and brain.

27 Apr 2010

Advair to remain favored fixed-dose LABA/ICS combination therapy through 2013 for asthma and COPD

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, despite increased competition from several emerging agents, GlaxoSmithKline's Advair will remain surveyed pulmonologists' and primary care physicians' (PCPs) favored fixed-dose long-acting beta2 agonist (LABA)/inhaled corticosteroid (ICS) combination inhaler through 2013 for the treatment of asthma and chronic obstructive pulmonary disease (COPD).

27 Apr 2010

Survey highlights need for continued education to reverse skin cancer epidemic in the U.S.

Results released today from a landmark national survey of dermatologists and consumers unveiled that there is a major gap between what dermatologists recommend and what Americans actually do when it comes to sun-safe behavior. This gap further highlights the need for continued education to reverse the skin cancer epidemic in the United States.

27 Apr 2010

Four unhealthy behaviors associated with increased risk of death when combined

Four unhealthy behaviors—smoking, lack of physical activity, poor diet and alcohol consumption—appear to be associated with a substantially increased risk of death when combined, according to a report in the April 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

27 Apr 2010

Researchers identify molecular marker of pancreatic cancer

Researchers at the University of North Carolina at Chapel Hill School of Medicine have identified a molecular marker of pancreatic cancer that may help spot the disease at its earliest stages, when it can be treated more successfully with surgery.

27 Apr 2010

Cellvizio probe-based confocal laser endomicroscopy to be featured at DDW 2010 conference

Mauna Kea Technologies, Inc., a leader in the in vivo cellular imaging market, announced that Cellvizio probe-based confocal laser endomicroscopy will be featured in key presentations at the annual Digestive Disease Week 2010 conference taking place in New Orleans May 1st thru the 5th.

27 Apr 2010

Avivia Health announces new portal with digital health coaching and interactive tools for employee members

To help employee members take a more proactive role in managing their own health programs, Avivia Health From Kaiser Permanente today announced the introduction of Your Health Center, a new portal based on Web 2.0 technology that provides user members with powerful digital health coaching and interactive tools. Avivia Health is the only national provider of Wellness and Condition Management Solutions based on 60 years of evidence-based practices by its parent organization, Kaiser Permanente.

27 Apr 2010

PositiveID, Receptors announce milestone in development of in vivo glucose-sensing RFID microchip

PositiveID Corporation, in conjunction with its development partner RECEPTORS LLC, announced today that the companies have achieved a milestone in the development of their in vivo glucose-sensing RFID microchip to detect glucose levels in the body. The companies have completed the synthesis of a new chemical building block that will serve as the anchor of their next generation of Combinatorial Artificial Receptor (CARA™) surfaces for the sensing system component of the implantable glucose sensor.

27 Apr 2010

New discovery links Slitrk5 gene to development of OCD-like behaviors

27 Apr 2010

Jefferson Medical College surgeon uses artificial liver assist device as bridge to transplantation

Cataldo Doria, M.D., Ph.D., Nicoletti Family Professor of Transplant Surgery at Jefferson Medical College of Thomas Jefferson University, and director of the Division of Transplantation at Thomas Jefferson University Hospital is the first transplant surgeon in the United States to use a new totally artificial liver assist device as a bridge to transplantation.

27 Apr 2010

Study suggests way to predict tumors most likely to respond to chemotherapy and radiation

Levels of a key type of immune cell are higher in head and neck cancer patients whose tumors are linked to the human papillomavirus, or HPV, according to researchers at the University of Michigan Comprehensive Cancer Center.

27 Apr 2010

LCT receives grant of $500,000 for Phase II clinical trial of DIABECELL in New Zealand

Living Cell Technologies Limited, a global company pioneering the development of a cell implant to treat diabetes, has received a grant of US$500,000 for its on-going Phase II clinical trial of DIABECELL in New Zealand from the Juvenile Diabetes Research Foundation International, a world leader in setting the agenda for diabetes research and the largest charitable funder and advocate for research in type 1 diabetes.

27 Apr 2010

PPD confirms Japanese approval for Takeda's NESINA NDA

PPD, Inc. today confirmed that Takeda Pharmaceutical Company Limited's new drug application for NESINA® (alogliptin), a highly selective DPP-4 inhibitor for the treatment of type 2 diabetes, was approved by the Japanese Ministry of Health, Labour and Welfare on April 16. PPD's compound partnering division collaborated with Takeda to develop this product.

27 Apr 2010

Evotec to receive EUR 1.5M from German BMBF for advancing H3 receptor antagonist programme

Evotec AG today announced that it will receive funding of up to EUR 1.5 million from the German Federal Ministry of Education and Research (BMBF) to advance its H3 receptor antagonist programme into the clinic.

27 Apr 2010

Researchers suggest association between mood and chocolate

Researchers at the University of California, San Diego School of Medicine have found that women and men eat more chocolate as depressive symptoms increase, suggesting an association between mood and chocolate.

27 Apr 2010

Tel Aviv University researcher maps drug target to wipe pain away

In most cases of chronic pain -- lingering pain that never seems to go away after accidents or prolonged illnesses ― no pill exists to dull the hurt. Billions of dollars are lost every year in sick days taken to alleviate chronic pain, and as much money is spent by the healthcare system to diagnose what's wrong.

27 Apr 2010

Study suggests potential ingredient in rice for prevention of cardiovascular diseases

Rice is generally thought to be a healthy addition to the diet because it is a source of fiber. However, not all rice is equally nutritious, and brown rice might have an advantage over white rice by offering protection from high blood pressure and atherosclerosis ("hardening of the arteries"), say researchers at the Cardiovascular Research Center and Department of Physiology at Temple University School of Medicine in Philadelphia.

27 Apr 2010

Medical Condition News

Scientists now closer to produce drugs to fix disease-causing mutations, spare healthy genes

Slitrk5 gene linked to development of OCD-like behaviors

Study links progression of lethal type of brain tumor with reduced expression of immune system genes

CocE exhibits potential for clinical treatment of cocaine toxicity

Advair to remain favored fixed-dose LABA/ICS combination therapy through 2013 for asthma and COPD

Survey highlights need for continued education to reverse skin cancer epidemic in the U.S.

Four unhealthy behaviors associated with increased risk of death when combined

Researchers identify molecular marker of pancreatic cancer

Cellvizio probe-based confocal laser endomicroscopy to be featured at DDW 2010 conference

Avivia Health announces new portal with digital health coaching and interactive tools for employee members

PositiveID, Receptors announce milestone in development of in vivo glucose-sensing RFID microchip

New discovery links Slitrk5 gene to development of OCD-like behaviors

Jefferson Medical College surgeon uses artificial liver assist device as bridge to transplantation

Study suggests way to predict tumors most likely to respond to chemotherapy and radiation

LCT receives grant of $500,000 for Phase II clinical trial of DIABECELL in New Zealand

PPD confirms Japanese approval for Takeda's NESINA NDA

Evotec to receive EUR 1.5M from German BMBF for advancing H3 receptor antagonist programme

Researchers suggest association between mood and chocolate

Tel Aviv University researcher maps drug target to wipe pain away

Study suggests potential ingredient in rice for prevention of cardiovascular diseases

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