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Study: Obesity-linked cancer deaths have tripled in the United States

Cancer deaths linked to obesity have tripled in the United States over the past two decades, according to a study being presented Sunday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

13 Jul 2025

How five months in Tibet changed the heart and lungs of Beijing workers

Long-term exposure to very high altitude significantly reduces cardiopulmonary function in healthy adults from lowland regions, as shown by declines in aerobic capacity and efficiency after five months in Lhasa, China.

13 Jul 2025

Is fruit juice good or bad for diabetes? New research reveals a genetic twist

Japanese adults with a high genetic risk for type 2 diabetes who consumed 100% fruit juice at least once per week had significantly lower odds of developing the disease. The inverse association was not seen in people with low or moderate genetic risk, highlighting gene-diet interactions.

13 Jul 2025

Ultra-processed foods threaten brain health in kids and teens, review warns

Children, adolescents, and unborn babies exposed to high levels of ultra-processed foods (UPFs) face increased risks of impaired brain development, cognitive deficits, and long-term mental health challenges. The review underscores how UPF-driven changes in reward pathways, nutrient deficits, inflammation, and the gut–brain axis can have lasting impacts across generations.

13 Jul 2025

Underactive thyroid linked to increased risk of small intestinal bacterial overgrowth

People with an underactive thyroid may have an increased risk of developing small intestinal bacterial overgrowth (SIBO), a risk that may be reduced with thyroid hormone treatment, according to a study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Adults over 80 benefit from osteoporosis medications

People who are older than 80 should be considered for osteoporosis treatment after a fracture to avoid further risk, according to a study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Higher protein intake may help prevent muscle loss in semaglutide users

Women and older adults taking the anti-obesity drug semaglutide may be at higher risk for muscle loss, but higher protein intake may help prevent muscle loss in these patients, according to a small study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Tirzepatide reduces obesity-associated breast cancer growth in mouse model

The anti-obesity medication tirzepatide, marketed as Mounjaro for diabetes and Zepbound for obesity, reduced obesity-associated breast cancer growth in a mouse model, according to a study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Long-term survival achieved in stage III melanoma with pre-surgery immunotherapy

Four years after pre-surgery treatment with a novel combination of immune checkpoint inhibitors, nivolumab and relatlimab, 87% of patients with stage III melanoma remained alive, according to new results from a study led by researchers at The University of Texas MD Anderson Cancer Center.

12 Jul 2025

Oral health function linked to markers of lifestyle-related diseases in older adults

The term 'oral health' refers to the health of the mouth, teeth, gums, and other related structures, and it is closely linked with our well-being and quality of life.

12 Jul 2025

Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies

In recent years, the regulatory role of the gut microbiota in the initiation and progression of colorectal cancer (CRC) has attracted growing attention. Among the key microbial contributors, Fusobacterium nucleatum (Fn) has been identified as a critical pathogenic factor in CRC.

12 Jul 2025

Stereotactic radiation shows promise for small cell lung cancer with brain metastases

A new study led by investigators from Mass General Brigham trialed stereotactic (targeted) brain-directed radiation in 100 patients with small cell lung cancer and brain metastases, finding they experienced positive outcomes that support use of targeted radiation in the future for such patients.

12 Jul 2025

Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by targeting immunosuppressive dendritic cells

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131-TNF signaling pathway-mediated differentiation of immunosuppressive dendritic cells.

12 Jul 2025

Melatonin receptor signaling counters sleep fragmentation-mediated infertility in T2DM

This new article publication from Acta Pharmaceutica Sinica B, discusses how melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1.

12 Jul 2025

High-intensity focused ultrasound induces ferroptosis for tumor immune activation

This new article publication from Acta Pharmaceutica Sinica B, discusses high intensity forced ultrasound-driven ferroptosis as a strategy for anti-tumor immune priming.

12 Jul 2025

Engineered exosomal spheres enhance melanoma immunotherapy through improved tumor penetration

This new article publication from Acta Pharmaceutica Sinica B, discusses the use of engineered platelet-derived exosomal spheres for enhanced tumor penetration and extended circulation in melanoma immunotherapy.

12 Jul 2025

CMD-OPT model enables discovery of potent and selective RIPK2 inhibitor for acute liver injury

This new article publication from Acta Pharmaceutica Sinica B, discusses how a CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury.

12 Jul 2025

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Metabolic dysfunction-associated steatotic liver disease (MASLD), affecting approximately 30% of the global population, represents a spectrum of liver disorders ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, and cirrhosis.

12 Jul 2025

Design strategies and therapeutic applications of smart materials in diabetes care

Announcing a new publication for Acta Materia Medica journal. Bioresponsive materials have gained prominence as innovative tools for advancing drug delivery systems, particularly in managing type 1 and type 2 diabetes mellitus.

12 Jul 2025

Teclistamab shows promising results in heavily pretreated multiple myeloma

Teclistamab-cqyv (Tecvayli) led to clinically meaningful responses in patients with heavily pretreated multiple myeloma who would have been ineligible for the MajesTEC-1 trial, and identified a novel factor independently associated with outcomes.

12 Jul 2025

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Medical Condition News

Study: Obesity-linked cancer deaths have tripled in the United States

How five months in Tibet changed the heart and lungs of Beijing workers

Is fruit juice good or bad for diabetes? New research reveals a genetic twist

Ultra-processed foods threaten brain health in kids and teens, review warns

Underactive thyroid linked to increased risk of small intestinal bacterial overgrowth

Adults over 80 benefit from osteoporosis medications

Higher protein intake may help prevent muscle loss in semaglutide users

Tirzepatide reduces obesity-associated breast cancer growth in mouse model

Long-term survival achieved in stage III melanoma with pre-surgery immunotherapy

Oral health function linked to markers of lifestyle-related diseases in older adults

Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies

Stereotactic radiation shows promise for small cell lung cancer with brain metastases

Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by targeting immunosuppressive dendritic cells

Melatonin receptor signaling counters sleep fragmentation-mediated infertility in T2DM

High-intensity focused ultrasound induces ferroptosis for tumor immune activation

Engineered exosomal spheres enhance melanoma immunotherapy through improved tumor penetration

CMD-OPT model enables discovery of potent and selective RIPK2 inhibitor for acute liver injury

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Design strategies and therapeutic applications of smart materials in diabetes care

Teclistamab shows promising results in heavily pretreated multiple myeloma

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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