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New DNA repair test could revolutionize treatment for genetic disorders and cancers

A personalised test that tells how well chemotherapy, radiotherapy or gene therapy will work on individual patients is now approved for UK, US, EU and Japanese patents.

10 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

How B-cells and androgens contribute to the development of PCOS

Researchers evaluate the role of B-cell frequencies in the pathogenesis of polycystic ovary syndrome.

9 Jul 2023

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Persistent immune activation and elevated cytokine levels were observed in patients with severe COVID-19, even months after recovery. However, the correlation between immune activation and long COVID symptoms appeared to be independent, suggesting other factors influencing disease severity.

9 Jul 2023

Unique plant extract mixture has potent anti-acne effects

Researchers evaluate the efficacy of FRO, a formula composed of fermented Rhus verniciflua Stokes and Orostachys japonicus, against acne pathogenesis via antimicrobial assessment and an in vitro analysis. FRO was found to contain phenolics such as gallic acid, fisetin, quercetin, and kaempferol and was determined to alleviate acne by inhibiting the growth of Cutibacterium acnes, inflammation, and excess sebum.

9 Jul 2023

New program offers hiking adventures for people with younger-onset Alzheimer's

Starting this July, people diagnosed with Alzheimer's before age 65 will have a new opportunity to connect with others while exploring the great outdoors through a program called SOAR. The name is an acronym for Shared Outdoor Adventures for Resilience.

7 Jul 2023

Bilateral total knee arthroplasty may increase risk of complications

Patients undergoing bilateral total knee arthroplasty (TKA) are at an increased risk of several types of complications, as compared with matched patients undergoing unilateral TKA, reports a study in The Journal of Bone & Joint Surgery.

7 Jul 2023

Research uncovers mechanism linking deep sleep to blood sugar control

Researchers have known that a lack of quality sleep can increase a person's risk of diabetes. What has remained a mystery, however, is why.

7 Jul 2023

Study traces the natural evolution of earliest stages of human cancers

Cancer cells-to-be accumulate a series of specific genetic changes in a predictable and sequential way years before they are identifiable as pre-malignancies, researchers at Stanford Medicine have found.

7 Jul 2023

Case report and review of a novel chromosomal abnormality in AML patient

A new research paper was published in Genes & Cancer on June 28, 2023, entitled, "A novel t (5; 17) (q35; q21) associated with t (8; 21) (q22; q22) in a patient with acute myeloid leukemia: case report and review of literature."

7 Jul 2023

MRI may be more effective than CT with CTA in patients with dizziness

According to an accepted manuscript published in the American Journal of Roentgenology (AJR), patients discharged from the emergency department (ED) after CT with CTA alone could have benefitted from an alternative or additional MRI evaluation, including using a specialized abbreviated protocol for the modality.

7 Jul 2023

MTB offers precision oncology strategy for advanced cancer patients

The collaborative group led by the Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed) and the Division of Clinical Pathology & Molecular Pathology, Hong Kong Sanatorium & Hospital (HKSH), have recently published their findings on the clinical importance of the Multidisciplinary Molecular Tumour Board (MTB) in delivering a Precision Cancer Medicine service.

7 Jul 2023

Study provides new insights into geographic differences in pain

The prevalence of moderate or severe joint pain due to arthritis varies strikingly across American states, ranging from 6.9% of the population in Minnesota to 23.1% in West Virginia, according to a new study led by a University at Buffalo researcher.

7 Jul 2023

Unique blood protein patterns in long COVID patients could reveal potential drug targets

Recently published in The Journal of Translational Medicine, a team at Lawson Health Research Institute has discovered unique patterns of blood plasma proteins in patients with long COVID that could reveal potential drug targets to improve patient outcomes.

7 Jul 2023

Joha rice variety shows promise as an option for people with diabetes

A scented rice variety grown in India's remote northeast, known as Joha rice, not only prevents type 2 diabetes but is also rich in unsaturated fatty acids, which work against heart disease, scientists have found.

7 Jul 2023

AI tool can rapidly decode brain tumor DNA during surgery

Scientists have designed an AI tool that can rapidly decode a brain tumor's DNA to determine its molecular identity during surgery - critical information that under the current approach can take a few days and up to a few weeks.

7 Jul 2023

Triple combination therapy shows promise in long-term treatment of cystic fibrosis

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF).

7 Jul 2023

Fecal transplants safe and effective in treating advanced melanoma, clinical trial shows

In a world-first clinical trial published in the journal Nature Medicine, a multi-center study from Lawson Health Research Institute, the Centre hospitalier de l'Université de Montréal and the Jewish General Hospital (JGH) has found fecal microbiota transplants (FMT) from healthy donors are safe and show promise in improving response to immunotherapy in patients with advanced melanoma.

7 Jul 2023

New molecular pathway identified for early onset coronary artery disease

A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s – with normal cholesterol levels and no other risk factors - to develop coronary artery disease has been identified, according to researchers with UTHealth Houston.

7 Jul 2023

Produce prescription programs could save US healthcare system $40 billion

An apple a day not only keeps the doctor away, it also could save the United States at least $40 billion in medical bills, report Friedman School of Nutrition Science and Policy at Tufts University researchers in a new study published July 7 in the Journal of the American Heart Association.

7 Jul 2023