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Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Study examines the relationship between pre-existing disease and COVID-19 outcomes in the Midwest

A study of more than three-quarters of a million Indiana COVID-19 cases is one of the first to focus on the disease in the Midwest.

22 Jun 2023

New standard more effective at preventing graft-versus-host disease

Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study published June 22 in the New England Journal of Medicine.

22 Jun 2023

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Dr. Niklas Klümper, resident at the Department of Urology and Pediatric Urology of the University Hospital Bonn (UKB) and working group leader at the Institute for Experimental Oncology (IEO), and Dr. Jonas Saal, resident at the Medical Clinic III for Oncology, Hematology, Immune-Oncology and Rheumatology of the UKB, demonstrated a significant improvement in predicting the response to therapy in metastatic renal cell carcinoma by incorporating the level of inflammation, which was assessed using two straightforward blood parameters, alongside the conventional imaging-based approach.

22 Jun 2023

World's largest gathering of NF community convenes in Arizona to advance research and care

From June 21 through June 27, the largest gathering of NF researchers, clinicians, and patients in the world will take place at the Fairmont Scottsdale Princess in Scottsdale, Arizona.

22 Jun 2023

New platform technology bridges the gap between microscopic analysis and multiplex imaging

Researchers at the Ludwig Center at Harvard have developed a platform technology for imaging that enables integration of the methods of microscopic analysis long employed in pathology laboratories with the visualization of multiple molecular markers in individual cells that is now rapidly advancing in research labs.

22 Jun 2023

Prior COVID-19 diagnosis linked to higher depression scores in incoming collegiate student-athletes

COVID-19 survivors may experience persistent neuropsychological disruptions such as lower satisfaction with life (SWLS), depression, and anxiety. While student-athletes are at low risk for severe COVID complications, the effect of COVID on mental health remains to be elucidated.

22 Jun 2023

Alzheimer's disease may begin during embryogenesis, stem cell study suggests

Alzheimer's disease (AD) mainly affects the older population. Recent research found early disease signs in cell culture models of early human brain development, raising the possibility that the disease has its origins much earlier in life, possibly during embryogenesis – the formation and development of an embryo.

22 Jun 2023

Brain organoids provide new insights into HSV-1 encephalitis

The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists with the Rajewsky and Landthaler labs and the Organoid Platform at the Max Delbrück Center in Nature Microbiology.

22 Jun 2023

New emotion recognition tool could help people with neurodiverse conditions

An emotion recognition tool - developed by University of the West of Scotland (UWS) academics - could help people with neurodiverse conditions including autism.

22 Jun 2023

MD Anderson and Ochsner Health join forces to advance cancer care in Louisiana

The University of Texas MD Anderson Cancer Center and New Orleans-based Ochsner Health today announced a partnership to create Ochsner MD Anderson Cancer Center in southeastern Louisiana.

22 Jun 2023

Parental cancer history associated with critical unmet needs of children

A new study by researchers at the American Cancer Society (ACS) found children of parents with a cancer history in the United States are more at risk of having unmet needs for housing, food, and other living necessities than their counterparts without a parental cancer history.

22 Jun 2023

First successful Phase 2 trial uses cutting-edge RNA CAR-T therapy to treat autoimmunity

The benefits and harms of screening and treatment for anxiety and the accuracy of instruments to detect anxiety among primary care patients

Researchers from the United States (U.S.) reviewed the risks and benefits of anxiety screening and treatment.

22 Jun 2023

Medical Condition News

Study reveals contrasting effects of sucralose on insulin and glucose control

Study examines the relationship between pre-existing disease and COVID-19 outcomes in the Midwest

New standard more effective at preventing graft-versus-host disease

Study finds new way to predict therapy response in metastatic renal cell carcinoma

World's largest gathering of NF community convenes in Arizona to advance research and care

New platform technology bridges the gap between microscopic analysis and multiplex imaging

Prior COVID-19 diagnosis linked to higher depression scores in incoming collegiate student-athletes

Alzheimer's disease may begin during embryogenesis, stem cell study suggests

Brain organoids provide new insights into HSV-1 encephalitis

New emotion recognition tool could help people with neurodiverse conditions

MD Anderson and Ochsner Health join forces to advance cancer care in Louisiana

Parental cancer history associated with critical unmet needs of children

First successful Phase 2 trial uses cutting-edge RNA CAR-T therapy to treat autoimmunity

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

High level of carotenes in the blood is associated with lesser atherosclerotic burden

A lower dietary carbohydrate/fat ratio may be effective in improving cognitive performance

Do Panax notoginseng saponins (Xuesaitong soft capsules) improve function in patients with ischemic stroke?

The invisible threat: gas stoves contaminate indoor air with benzene

The benefits and harms of screening and treatment for anxiety and the accuracy of instruments to detect anxiety among primary care patients

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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