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Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

SARS-CoV-2 infection significantly impacts cognitive function in patients with preexisting dementia

Infection with SARS-CoV-2 has a significant impact on cognitive function in patients with preexisting dementia, according to new research, published in the Journal of Alzheimer's Disease Reports.

4 Apr 2023

TiY: Cancer diagnosis and treatment in a single step

Cancer is not incurable anymore. Nevertheless, according to statistics released by Statistics Korea last year, cancer remained the primary cause of mortality in Korea in 2021.

4 Apr 2023

Getting sick often may increase the risk of dementia

Getting sick often may impact how quickly the brain ages and increase the risk of dementia or other forms of cognitive decline.

4 Apr 2023

Promoting cellular recycling in the brain may reverse or prevent damage from traumatic brain injury

Each year about 1.5 million people in the U.S. survive a traumatic brain injury due to a fall, car accident, or a sports injury, which can cause immediate and long-term disability.

4 Apr 2023

New model for proteomic cardiovascular risk assessment among chronic kidney disease patients

Chronic kidney disease (CKD) is a strong cardiovascular risk factor and is often accompanied by hypertension and diabetes. Despite the disease's prevalence - 10 percent of individuals across the globe suffer from CKD - there are limited tools for measuring cardiac risk for CKD patients, until now.

4 Apr 2023

Novel immunotherapy-based approach for low-grade lymphomatoid granulomatosis improves patient survival

Results from a clinical trial conducted by researchers at the National Institutes of Health (NIH) show that people with low-grade lymphomatoid granulomatosis who are treated with interferon alfa-2b, a type of immunotherapy, can live for decades after diagnosis.

4 Apr 2023

Blood-based biomarkers for Alzheimer’s disease could make diagnostic workup more accurate, cost-effective

An international research team led by the HUG and the UNIGE has shown that amyloid and tau blood-based biomarkers are highly correlated with the corresponding biomarkers used so far for the diagnosis of Alzheimer's disease.

4 Apr 2023

Innovative approach to customize treatments for colorectal cancer

How to determine the most effective treatment for colon cancer? The response to chemotherapy varies greatly from one patient to another.

4 Apr 2023

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

A team led by engineers at the University of California San Diego has developed a biodegradable polymer system to treat rheumatoid arthritis, an autoimmune and inflammatory disease, by working in concert with the power of the human immune system.

4 Apr 2023

What role do dietary lipids play in the gut-brain axis in type 2 diabetes mellitus?

Researchers examined the significance of dietary lipids in the gut-brain axis of individuals with T2DM.

4 Apr 2023

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease - about a half million people in the United States alone suffer from the condition.

4 Apr 2023

Two-drug combination may offer a new way to treat inflammatory bowel diseases, study suggests

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

4 Apr 2023

Fatigue is common among older adults, and it has many possible causes

Nothing prepared Linda C. Johnson of Indianapolis for the fatigue that descended on her after a diagnosis of stage 4 lung cancer in early 2020.

4 Apr 2023

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Researchers assessed the cellular and molecular level immunopathology of PCLD.

4 Apr 2023

Life's Essential 8: Higher cardiovascular health scores linked to reduced mortality risks

Cardiovascular disease (CVD) is one of the most significant causes of global mortality. Several factors, such as obesity, poor diet, lack of physical activity, dyslipidemia, smoking, diabetes, and high blood pressure, have been identified to enhance the risk of CVD events. In 2010, the American Heart Association (AHA) constructed Life’s Simple 7, which included seven lifestyle-based goals that could help achieve ideal cardiovascular health (CVH).

4 Apr 2023

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

Researchers conduct a cross-sectional survey to estimate SARS-CoV-2 antibodies in children.

3 Apr 2023

Birth weight and maternal BMI modify the relationship between obesity and mortality rate

Obesity is a significant risk factor for premature mortality due to the predisposition to metabolic and cardiovascular disease. However, is this effect independent of the birth weight? A new research paper examines this aspect of adult obesity, measuring the effect of parental body mass index (BMI) and birth weight on the mortality risk.

3 Apr 2023

Study investigates vitamin C's effectiveness in treating gout and hyperuricemia

Scientists at the University of Minnesota, USA, have initiated a study entitled “the Hmong Microbiome and Gout, Obesity, Vitamin C (HMANGO-C) study” to determine the effect of vitamin C supplementation on serum urate levels in Hmong adults with or without gout. Hmong (pronounced mung) is a racial group originally from the Southwest of China.

3 Apr 2023

Study: Medicaid reimbursement for the same mental health treatment varies among U.S. states

Medicaid reimbursement for the same mental health treatment varies dramatically among U.S. states, according to a new study by researchers at Oregon Health & Science University.

3 Apr 2023

Medical Condition News

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

SARS-CoV-2 infection significantly impacts cognitive function in patients with preexisting dementia

TiY: Cancer diagnosis and treatment in a single step

Getting sick often may increase the risk of dementia

Promoting cellular recycling in the brain may reverse or prevent damage from traumatic brain injury

New model for proteomic cardiovascular risk assessment among chronic kidney disease patients

Novel immunotherapy-based approach for low-grade lymphomatoid granulomatosis improves patient survival

Blood-based biomarkers for Alzheimer’s disease could make diagnostic workup more accurate, cost-effective

Innovative approach to customize treatments for colorectal cancer

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

What role do dietary lipids play in the gut-brain axis in type 2 diabetes mellitus?

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

Two-drug combination may offer a new way to treat inflammatory bowel diseases, study suggests

Fatigue is common among older adults, and it has many possible causes

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Life's Essential 8: Higher cardiovascular health scores linked to reduced mortality risks

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

Birth weight and maternal BMI modify the relationship between obesity and mortality rate

Study investigates vitamin C's effectiveness in treating gout and hyperuricemia

Study: Medicaid reimbursement for the same mental health treatment varies among U.S. states

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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