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New genetic animal model may inform potential therapeutic options for Down syndrome

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be more similar to the changes seen in humans.

14 Mar 2023

Scientists find a good treatment target for pulmonary hypertension

The vascular smooth muscle cells that normally give blood vessel walls strength and flexibility proliferate and become destructive in pulmonary hypertension, a typically rapidly progressing condition that makes it hard to get blood inside our lungs and oxygen to our bodies.

14 Mar 2023

Hunger hormone can increase the heart's pump capacity in patients with heart failure

A clinical study by researchers at Karolinska Institutet and Karolinska University Hospital in Sweden shows that the hunger hormone ghrelin can increase the heart's pump capacity in patients with heart failure.

14 Mar 2023

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs) - specialized molecules that can modulate RNA and alter protein production - directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

14 Mar 2023

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.

14 Mar 2023

Using antagonistic drug combinations for selective killing of resistant cancer cells

A new review paper was published in Oncotarget's Volume 14 on March 11, 2023, entitled, "Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells."

14 Mar 2023

Cherenkov color imaging holds potential to make radiation therapy safer and more effective

Cherenkov imaging is a valuable cancer treatment tool that can help doctors track and monitor radiation doses received by tissues during cancer therapy in real time.

14 Mar 2023

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma - the deadliest type of primary brain cancer - and other solid tumors.

14 Mar 2023

ESC Preventive Cardiology 2023 puts spotlight on heart disease prevention strategies

Get ready for practice-changing science at ESC Preventive Cardiology 2023, a scientific congress of the European Society of Cardiology.

14 Mar 2023

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Scientists at the National Institutes of Health and Massachusetts General Hospital in Boston have uncovered a potential new approach against liver cancer that could lead to the development of a new class of anticancer drugs.

14 Mar 2023

Black lung resurgence drives push to protect coal miners against silica dust

Like most coal miners' loved ones, Liz Williams has endured many days and nights of worry.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

Revamping lifestyle can bolster brain health and stave off neurocognitive decline

In a recent article published in the journal Cureus, researchers at Loma Linda University Medical Center and the University of California Irvine reviewed the impact of applying the six pillars of lifestyle medicine — stress management, plant-based nutrition, avoidance of risky substances, physical activity, social connections, and restorative sleep — on neurocognitive decline and dementia.

14 Mar 2023

Hurricane exposure associated with increased mortality among older adults living with dementia

Previous studies of hurricanes have shown general increases in mortality but little has been known about how mortality following hurricane exposure may differ among older adults living with dementia.

13 Mar 2023

Consuming low-insulin-stimulating bread significantly reduces body weight

Substituting common insulinogenic bread with bread releasing low levels of inulin could significantly reduce weight among obese individuals.

13 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy.

13 Mar 2023

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

13 Mar 2023

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

A new study by Columbia University researchers suggests that cholesterol-lowering drugs called statins have the potential to reduce heart disease in people with obstructive sleep apnea regardless of the use of CPAP machines during the night.

13 Mar 2023

Innate immune molecule could be at the root of ALS

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures.

13 Mar 2023

Medical Condition News

New genetic animal model may inform potential therapeutic options for Down syndrome

Scientists find a good treatment target for pulmonary hypertension

Hunger hormone can increase the heart's pump capacity in patients with heart failure

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

Using antagonistic drug combinations for selective killing of resistant cancer cells

Cherenkov color imaging holds potential to make radiation therapy safer and more effective

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

ESC Preventive Cardiology 2023 puts spotlight on heart disease prevention strategies

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Black lung resurgence drives push to protect coal miners against silica dust

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

Revamping lifestyle can bolster brain health and stave off neurocognitive decline

Hurricane exposure associated with increased mortality among older adults living with dementia

Consuming low-insulin-stimulating bread significantly reduces body weight

Hyperinflammation triggers long COVID headaches

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

Innate immune molecule could be at the root of ALS

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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