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Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Study examines the relationship between pre-existing disease and COVID-19 outcomes in the Midwest

A study of more than three-quarters of a million Indiana COVID-19 cases is one of the first to focus on the disease in the Midwest.

22 Jun 2023

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Dr. Niklas Klümper, resident at the Department of Urology and Pediatric Urology of the University Hospital Bonn (UKB) and working group leader at the Institute for Experimental Oncology (IEO), and Dr. Jonas Saal, resident at the Medical Clinic III for Oncology, Hematology, Immune-Oncology and Rheumatology of the UKB, demonstrated a significant improvement in predicting the response to therapy in metastatic renal cell carcinoma by incorporating the level of inflammation, which was assessed using two straightforward blood parameters, alongside the conventional imaging-based approach.

22 Jun 2023

Prior COVID-19 diagnosis linked to higher depression scores in incoming collegiate student-athletes

COVID-19 survivors may experience persistent neuropsychological disruptions such as lower satisfaction with life (SWLS), depression, and anxiety. While student-athletes are at low risk for severe COVID complications, the effect of COVID on mental health remains to be elucidated.

22 Jun 2023

Alzheimer's disease may begin during embryogenesis, stem cell study suggests

Alzheimer's disease (AD) mainly affects the older population. Recent research found early disease signs in cell culture models of early human brain development, raising the possibility that the disease has its origins much earlier in life, possibly during embryogenesis – the formation and development of an embryo.

22 Jun 2023

High-volume surgeons linked to better patient outcomes after shoulder replacement surgery

Patients treated by surgeons who average over 10 shoulder replacements a year have a lower risk of reoperation and serious complications, and a shorter hospital stay than those treated by surgeons who do fewer operations, finds a study published by The BMJ today.

22 Jun 2023

Plant-based foods may be a key to preventing childhood obesity

A new study led by researchers from the Mass General Brigham healthcare system suggests that taking a "food is medicine" approach could increase nutrition security for families and lead to reductions in body mass index (BMI) in children.

22 Jun 2023

Parental cancer history associated with critical unmet needs of children

A new study by researchers at the American Cancer Society (ACS) found children of parents with a cancer history in the United States are more at risk of having unmet needs for housing, food, and other living necessities than their counterparts without a parental cancer history.

22 Jun 2023

How abortion restrictions affect research on people who may become pregnant

In this Policy Forum, Jeremy Sugarman and colleagues describe the risks that increasingly limited access to abortion may pose to clinical research participants and staff, one year after the U.S. Supreme Court's decision in Dobbs v. Jackson Woman's Health Organization.

22 Jun 2023

Emergency department capacity has not kept up with patient demand in California, study finds

Explaining why wait times can be so lengthy in the emergency room, a new study by UC San Francisco reports that emergency department capacity hasn't kept up with patient demand in California over the last decade.

22 Jun 2023

Local healthcare options lead to better outcomes for the elderly

Older people with health problems often need some form of intermediate level monitoring, care and treatment services.

22 Jun 2023

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Leishmaniasis is a tropical disease caused by parasites known as Leishmania, which are transmitted to humans and animals through the bites of more than 90 species of sand flies.

22 Jun 2023

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

There are still many enigmas about the mechanism of action of metformin, the most prescribed drug to treat diabetes mellitus, also known as type 2 diabetes.

22 Jun 2023

Neurons involved in creating negative emotional states and chronic stress identified

Researchers at Karolinska Institutet in Sweden have identified a group of nerve cells in the mouse brain that are involved in creating negative emotional states and chronic stress. The

22 Jun 2023

High level of carotenes in the blood is associated with lesser atherosclerotic burden

A high level of carotenes in the blood is linked with a lower degree of atherosclerosis in the arteries and thus a lower risk of cardiovascular diseases.

22 Jun 2023

Tranexamic acid use linked to decreased incidence of heterotopic ossification after elbow trauma surgery

For patients undergoing surgery for elbow trauma, treatment with the hemostatic drug tranexamic acid (TXA) is associated with a decreased incidence of heterotopic ossification (HO) – a common complication of abnormal bone formation, reports a study in The Journal of Bone & Joint Surgery.

22 Jun 2023

Research sheds light on continuous development of social understanding from adolescence into early adulthood

The capability to reflect on their own mental state and that of others continues to develop throughout adolescence, with mentalizing scores varying by gender and personality traits, according to a new study published this week in the open-access journal PLOS ONE by Alex Desatnik of University College London, UK, and colleagues.

22 Jun 2023

Feeling high associated with improved symptom relief but increased negative side effects in medical cannabis patients

In a new study titled, "Understanding Feeling 'High' and Its Role in Medical Cannabis Patient Outcomes," published in the journal, Frontiers in Pharmacology, researchers at The University of New Mexico, in collaboration with Releaf App™ found that patients who reported feeling "High" experienced 7.7% greater symptom relief and an increase in reporting of positive side effects such as "Relaxed" and "Peaceful."

22 Jun 2023

UQ researchers uncover the structure of Langya virus' fusion protein

Researchers have shed light on how a highly infectious virus, that has recently transferred from animals to people, is able to enter human cells.

22 Jun 2023

A lower dietary carbohydrate/fat ratio may be effective in improving cognitive performance

Study describes that a low dietary carbohydrate/fat ratio is good for cognitive health in older adults at risk for dementia.

22 Jun 2023

Medical Research News

Study reveals contrasting effects of sucralose on insulin and glucose control

Study examines the relationship between pre-existing disease and COVID-19 outcomes in the Midwest

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Prior COVID-19 diagnosis linked to higher depression scores in incoming collegiate student-athletes

Alzheimer's disease may begin during embryogenesis, stem cell study suggests

High-volume surgeons linked to better patient outcomes after shoulder replacement surgery

Plant-based foods may be a key to preventing childhood obesity

Parental cancer history associated with critical unmet needs of children

How abortion restrictions affect research on people who may become pregnant

Emergency department capacity has not kept up with patient demand in California, study finds

Local healthcare options lead to better outcomes for the elderly

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

Neurons involved in creating negative emotional states and chronic stress identified

High level of carotenes in the blood is associated with lesser atherosclerotic burden

Tranexamic acid use linked to decreased incidence of heterotopic ossification after elbow trauma surgery

Research sheds light on continuous development of social understanding from adolescence into early adulthood

Feeling high associated with improved symptom relief but increased negative side effects in medical cannabis patients

UQ researchers uncover the structure of Langya virus' fusion protein

A lower dietary carbohydrate/fat ratio may be effective in improving cognitive performance

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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