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Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

In a recent study posted to the bioRxiv* preprint server, researchers engineered epitope scaffolds (ESs) of conserved regions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

3 Mar 2023

Age-associated B cells found to be important drivers of lupus

A group of University of Pittsburgh researchers has given new meaning to "knowing your ABCs."

3 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Maternal obesity associated with adverse metabolic health outcomes in childhood

Research by the University of the Basque Country indicates that changes caused by maternal obesity could lead to adverse health outcomes in childhood.

3 Mar 2023

Socioecological variables and anthocyanin-rich food consumption

Researchers assessed the socioecological variables affecting older people's intake of anthocyanin-rich foods.

3 Mar 2023

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Researchers elucidated immunologic and genetic perturbations in long COVID patients with pulmonary fibrosis.

3 Mar 2023

Adults and children mostly have only one of the classical 'triad' of meningitis symptoms, research shows

Prompt recognition of symptoms and treatment is vital for good outcomes in cases of meningitis.

3 Mar 2023

Former players’ cognitive performance associated with concussion symptoms during football careers

Former professional football players who reported experiencing concussion symptoms during their playing careers were found to perform worse on a battery of cognitive tests than non-players, according to a study led by Mass General Brigham investigators from McLean Hospital and Spaulding Rehabilitation Network.

3 Mar 2023

Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17?

Researchers conducted a population-based cohort study among 12 to 17-year-old adolescents in Ontario, Canada, to estimate the incidence of myocarditis or pericarditis after BNT162b2 vaccination.

3 Mar 2023

Large-scale longitudinal study of neutralizing antibody responses to norovirus in children

Researchers characterized serological neutralizing antibody responses to norovirus among young children, transitioning between sequential GII.4 pandemic strains, DH 2006, NO 2009, and SY 2012.

3 Mar 2023

Study estimates and compares excess mortality due to cardiovascular diseases across multiple pandemic waves in the US

Researchers estimated excess cardiovascular deaths in the USA between March 2020 and March 2022.

3 Mar 2023

Cirrhosis associated with lower immune responses to COVID-19 vaccines in patients with chronic liver disease

The overall responsiveness of patients with chronic liver disease (CLD) to COVID-19 vaccines has been shown to be decreased in patients with cirrhosis.

2 Mar 2023

Alarming Projection: By 2035, more than half of the global population will be obese

The World Obesity Atlas predicts that over 51% of the world population will be considered obese by 2035.

2 Mar 2023

Study estimates the carbon footprint and diet quality of popular U.S. diets

A new research paper looks at several popular diets and what it costs the environment to follow any of them, contrasting with their real-life benefits regarding diet quality.

2 Mar 2023

Serious pneumococcal infection increases the risk of a heart attack significantly

After the onset of serious pneumococcal infections, patients are at a significantly increased risk of having a heart attack, according to a Vanderbilt study published in the journal Clinical Infectious Diseases.

2 Mar 2023

Adding evidence to the weight gain causality of sugary drinks

The review, published in the American Journal of Clinical Nutrition, is the most extensive analysis to date of research on sweetened drinks and overweight and obesity - both of which heighten risks for diabetes, heart disease, some cancers, and other diseases.

2 Mar 2023

Research identifies a possible treatment strategy for rare bone marrow failure syndrome

Bone marrow is the spongy tissue inside bone responsible for making red blood cells, white blood cells and platelets. Bone marrow failure syndromes lead to an increased risk of developing dangerous infections, anemia and an increased risk of blood cancers.

2 Mar 2023

Immune activity differs for pregnant women based on anxiety status

The immune system of pregnant women with anxiety is biologically different from that of pregnant women without anxiety, according to new research from Weill Cornell Medicine, Johns Hopkins University School of Medicine and Columbia University Irving Medical Center investigators.

2 Mar 2023

Neural underpinnings of atypical visual sensory behaviors in some children with autism

There is this picture – you may have seen it. It is black and white and has two silhouettes facing one another. Or maybe you see the black vase with a white background. But now, you likely see both.

2 Mar 2023

New research could greatly improve the quality of life for patients with temporal lobe epilepsy

Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy, opening the door to a therapy using electrodes that could be activated to prevent seizures from happening, according to new research from UTHealth Houston.

2 Mar 2023

Medical Research News

Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

Age-associated B cells found to be important drivers of lupus

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Maternal obesity associated with adverse metabolic health outcomes in childhood

Socioecological variables and anthocyanin-rich food consumption

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Adults and children mostly have only one of the classical 'triad' of meningitis symptoms, research shows

Former players’ cognitive performance associated with concussion symptoms during football careers

Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17?

Large-scale longitudinal study of neutralizing antibody responses to norovirus in children

Study estimates and compares excess mortality due to cardiovascular diseases across multiple pandemic waves in the US

Cirrhosis associated with lower immune responses to COVID-19 vaccines in patients with chronic liver disease

Alarming Projection: By 2035, more than half of the global population will be obese

Study estimates the carbon footprint and diet quality of popular U.S. diets

Serious pneumococcal infection increases the risk of a heart attack significantly

Adding evidence to the weight gain causality of sugary drinks

Research identifies a possible treatment strategy for rare bone marrow failure syndrome

Immune activity differs for pregnant women based on anxiety status

Neural underpinnings of atypical visual sensory behaviors in some children with autism

New research could greatly improve the quality of life for patients with temporal lobe epilepsy

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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