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Trial establishes the clinical utility of circulating tumor cell count as biomarker in breast cancer care

The use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine therapy as first-line therapy for patients with metastatic, estrogen receptor (ER)-positive/HER2-negative breast cancer provided overall survival benefit, compared with physician's choice of treatment, according to data from the STIC CTC trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

8 Dec 2022

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma – a lethal form of salivary gland cancer that currently has no treatment options.

8 Dec 2022

Understanding soundscapes in day cares can pave the way toward better child care

During some of their most formative years, many children go to day care centers outside their homes. While there, they require a supportive, healthy environment that includes meaningful speech and conversation. This hinges on the soundscape of the child care center.

8 Dec 2022

Novel gene mutation linked to rare premature-aging syndrome

UT Southwestern researchers have discovered a new form of progeria, a rare premature-aging syndrome, in a man from Malaysia and traced its cause to a novel gene mutation.

8 Dec 2022

Researchers receive $11 million NIH grant to evaluate a 5-minute dementia screening tool

Investigators at Albert Einstein College of Medicine, Montefiore Health System, Regenstrief Institute, and Indiana University School of Medicine have received an $11 million grant from the National Institutes of Health to evaluate an Einstein-developed test for assessing cognitive impairment and dementia.

8 Dec 2022

Pay volatility linked to worse physical health symptoms

Gig workers, waiters, salespeople and others who rely on fluctuating income may be paying for wage volatility with their health, according to research published by the American Psychological Association.

8 Dec 2022

Genetic predisposition to ADHD can predict risk of late-onset Alzheimer's disease

Genetic predisposition to attention-deficit/hyperactivity disorder (ADHD) can predict cognitive decline and Alzheimer's disease later in life, revealed an analysis published today in Molecular Psychiatry by University of Pittsburgh School of Medicine researchers.

8 Dec 2022

Addition of yoga to regular exercise training supports cardiovascular health and wellbeing

A three-month pilot study of patients with hypertension appearing in the Canadian Journal of Cardiology, published by Elsevier, demonstrates that adding yoga to a regular exercise training regimen supports cardiovascular health and wellbeing and is more effective than stretching exercises.

8 Dec 2022

COVID-19 vaccines may reduce long-COVID symptoms

A new study describes the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in reducing long-COVID symptoms.

8 Dec 2022

Exploring a variant-adapted SARS-CoV-2 recombinant protein vaccine

Researchers assessed the immunogenicity of a variant-adapted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recombinant protein vaccine boosted with an AS03 adjuvant.

8 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Adult females exhibit impaired muscle and pulmonary function after COVID-19 recovery

In a new study, researchers examined muscle and pulmonary dysfunction during moderate exercise in adult females who recovered from coronavirus disease 2019 (COVID-19).

8 Dec 2022

Exploring COVID-19 vaccination prioritization strategies for primary and booster doses

Researchers evaluated the coronavirus disease 2019 (COVID-19) vaccine, prioritizing options for primary and booster doses.

8 Dec 2022

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Researchers evaluated individuals who had SARS-CoV-2 infections and were diagnosed with diabetes mellitus within six months of the onset of COVID-19 to understand the temporal relationship between SARS-CoV-2 infections and diabetes mellitus.

8 Dec 2022

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Researchers investigated the immunological mechanisms behind the decreasing efficacy of COVID-19 vaccines by evaluating the durability and magnitude of neutralizing antibodies and memory B and T cell responses to booster doses of mRNA COVID-19 vaccine.

8 Dec 2022

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Fatty foods harm our health. Prior research has established a link between the consumption of dietary fats and non-alcoholic fatty liver disease, which subsequently leads to inflammation and tumor formation in the liver.

7 Dec 2022

Low-intensity ultrasound therapies may help rebuild stronger knees

Low-intensity ultrasound therapies may one day rebuild stronger knees following injury or surgery, thanks to research by Dr. Anu Subramanian at The University of Alabama in Huntsville (UAH) that's being supported by the National Institutes of Health.

7 Dec 2022

UKSRC researchers work with community partners to protect Kentuckians from 'forever chemicals'

Nearly every person in the United States has been exposed to per- and polyfluorinated alky substances (PFAS) at some point in their life.

7 Dec 2022

New 'heart attack on a chip' could serve as a testbed to develop personalized medicines

Researchers at the University of Southern California Alfred E. Mann Department of Biomedical Engineering have developed a "heart attack on a chip," a device that could one day serve as a testbed to develop new heart drugs and even personalized medicines.

7 Dec 2022

Buprenorphine prescription remained constant during the first year of COVID-19 pandemic

The number of active prescriptions for the opioid disorder treatment drug buprenorphine remained constant during the first year of the COVID-19 pandemic, but the number of new prescriptions for the treatment was far below what would normally have been expected, according to a new RAND Corporation study.

7 Dec 2022

Medical Research News

Trial establishes the clinical utility of circulating tumor cell count as biomarker in breast cancer care

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

Understanding soundscapes in day cares can pave the way toward better child care

Novel gene mutation linked to rare premature-aging syndrome

Researchers receive $11 million NIH grant to evaluate a 5-minute dementia screening tool

Pay volatility linked to worse physical health symptoms

Genetic predisposition to ADHD can predict risk of late-onset Alzheimer's disease

Addition of yoga to regular exercise training supports cardiovascular health and wellbeing

COVID-19 vaccines may reduce long-COVID symptoms

Exploring a variant-adapted SARS-CoV-2 recombinant protein vaccine

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Adult females exhibit impaired muscle and pulmonary function after COVID-19 recovery

Exploring COVID-19 vaccination prioritization strategies for primary and booster doses

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Low-intensity ultrasound therapies may help rebuild stronger knees

UKSRC researchers work with community partners to protect Kentuckians from 'forever chemicals'

New 'heart attack on a chip' could serve as a testbed to develop personalized medicines

Buprenorphine prescription remained constant during the first year of COVID-19 pandemic

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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