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Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

Researchers assessed several approaches for a circulating cell-free deoxyribonucleic acid (cfDNA)-based multi-cancer early detection (MCED) test. Defining the clinical limit of detection (LOD) based on circulating tumor allele fraction (cTAF) enables the comparison of different approaches.

21 Nov 2022

WHO‒recommended alcohol-based hand rub formulations show efficacy against Monkeypox virus

Researchers demonstrated the efficacy of two World Health Organization (WHO)‒recommended alcohol-based hand rub solutions to inactivate the monkeypox virus (MPXV).

21 Nov 2022

Transgender teens and young adults four times more likely to have a sleep disorder

Teens and young adults who are transgender are four times more likely to have a sleep disorder compared to cisgender youth, a Michigan Medicine-led study finds.

21 Nov 2022

Exercise may make radiotherapy more tolerable for breast cancer patients

Breast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer by the age of 85.

21 Nov 2022

Increase in Candida auris infections among EU/EEA nations between 2020 and 2021

Researchers evaluated the trends in Candida auris infections among European Union/European Economic Area (EU/EUA) nations between 2020 and 2021.

21 Nov 2022

Hungary sees 116% growth in non-invasive prenatal testing

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From BGI Genomics 21 Nov 2022

MRI reveals brain changes in patients up to six months after COVID-19 recovery

Using a special type of MRI, researchers have uncovered brain changes in patients up to six months after they recovered from COVID-19, according to a study being presented next week at the annual meeting of the Radiological Society of North America.

21 Nov 2022

Anti-inflammatory pain relievers may worsen inflammation in osteoarthritis

Taking anti-inflammatory pain relievers like ibuprofen and naproxen for osteoarthritis may worsen inflammation in the knee joint over time, according to a new study being presented next week at the annual meeting of the Radiological Society of North America.

21 Nov 2022

What is the association between particulate matter exposure and SARS-CoV-2 infections?

In a new study, researchers assessed the association between particulate matter ≤2.5mm (PM2.5) exposure and SARS-CoV-2 infection and severity outcomes such as hospitalizations and deaths.

21 Nov 2022

Chitin-immobilized nanobodies for SARS-CoV-2 detection

Researchers demonstrated a novel strategy to detect SARS-CoV-2 using chitin-immobilized nanobodies.

21 Nov 2022

Tackling Antimicrobial Resistance; A Conversation with the World Health Organisation

For World Antimicrobial Awareness Week (WAAW), we speak to Silvia Bertagnolio from the WHO, about the importance of raising awareness of antimicrobial resistance.

21 Nov 2022

SARS-CoV-2 infection and mRNA vaccination prime transcriptionally distinct CD4+ T cell memory landscapes

Researchers reported that SARS-CoV-2 infection and mRNA vaccination induce distinct memory T cells.

21 Nov 2022

Enormous rise in Acinetobacter bloodstream infection cases in initial two years of COVID-19

In a new study, researchers investigated Acinetobacter species bloodstream infection (BSI) case counts from a subset of laboratory data continuously reported during the initial two years of SARS-CoV-2 infections, i.e., from 2020 to 2021.

21 Nov 2022

Does influenza vaccination reduce death and vascular events in patients with heart failure?

Researchers conducted a placebo-controlled, double-blind clinical trial to assess whether influenza vaccination effectively reduced vascular events and mortality among patients with heart failure.

21 Nov 2022

Frozen and viable: successful culture of replicating SARS-CoV-2 from hospital aerosol samples after freezing

Researchers demonstrated the presence of infectious SARS-CoV-2 in samples from the hospital rooms of SARS-CoV-2-infected patients.

21 Nov 2022

CAR T-cell therapy in colorectal cancer

Researchers assessed the efficacy of CAR T-cells in the immunotherapy of colorectal cancer.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

New discovery increases understanding of the effects of narcolepsy on the brain

Narcolepsy alters the pulsations that maintain the brain’s waste clearance system, shows a new study from the University of Oulu. The researchers’ discovery increases our understanding of the effects of narcolepsy on the brain, and may also help in the diagnosis of the disease.

21 Nov 2022

Study provides a more accurate tool to stratify patients with HER2-positive breast cancer

Patients with a type of breast cancer called HER2-positive are less likely to survive if their initial treatment fails to eradicate the tumor completely and they have high levels of immune cells called tumor-infiltrating lymphocytes in the residual disease.

21 Nov 2022

The role of bacteria in cancer growth

Tumor-associated microbiota is an important component of the tumor microenvironment (TME) across 33 types of human cancer. However, little evidence is available regarding the spatial distribution and localization of these microbes in tumor cells.

20 Nov 2022

Medical Research News

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

WHO‒recommended alcohol-based hand rub formulations show efficacy against Monkeypox virus

Transgender teens and young adults four times more likely to have a sleep disorder

Exercise may make radiotherapy more tolerable for breast cancer patients

Increase in Candida auris infections among EU/EEA nations between 2020 and 2021

Hungary sees 116% growth in non-invasive prenatal testing

MRI reveals brain changes in patients up to six months after COVID-19 recovery

Anti-inflammatory pain relievers may worsen inflammation in osteoarthritis

What is the association between particulate matter exposure and SARS-CoV-2 infections?

Chitin-immobilized nanobodies for SARS-CoV-2 detection

Tackling Antimicrobial Resistance; A Conversation with the World Health Organisation

SARS-CoV-2 infection and mRNA vaccination prime transcriptionally distinct CD4+ T cell memory landscapes

Enormous rise in Acinetobacter bloodstream infection cases in initial two years of COVID-19

Does influenza vaccination reduce death and vascular events in patients with heart failure?

Frozen and viable: successful culture of replicating SARS-CoV-2 from hospital aerosol samples after freezing

CAR T-cell therapy in colorectal cancer

Study suggests bats are an underrecognized arenavirus reservoir

New discovery increases understanding of the effects of narcolepsy on the brain

Study provides a more accurate tool to stratify patients with HER2-positive breast cancer

The role of bacteria in cancer growth

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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