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Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Researchers evaluated to what extent prior infection and vaccination protected the residents and staff of the United States California state prison system from breakthrough infection by SARS-CoV-2 Omicron sub-variant B.1.1.529.

28 Oct 2022

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

A new study confirmed that the SARS-CoV-2 spike protein does not bind to human AChR’s orthosteric sites, nor does it compete with ACh, choline, or nicotine.

28 Oct 2022

What are the contemporary hazards of cigarette smoking and benefits of quitting smoking by race, ethnicity, and sex among US adults?

Researchers quantified the association between cigarette smoking and all-cause and cause-specific deaths by sex, ethnicity, and race.

28 Oct 2022

E-cigarette use alters respiration but does not impair lung function, according to new findings

A new study indicated that although vaping increases airway resistance, it does not impact lung function.

28 Oct 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

The dynamics of COVID-19 conspiracist ideation

Researchers studied the dynamics of COVID-19 conspiracist ideation—a general tendency to believe in conspiracy theories.

28 Oct 2022

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.

28 Oct 2022

ADOS testing not required for ASD diagnosis by developmental-behavioral pediatricians

Trained developmental-behavioral pediatricians can generally diagnose autism spectrum disorder (ASD) in young children without the need for additional Autism Diagnostic Observation Schedule (ADOS) testing, finds a prospective multicenter study.

28 Oct 2022

Low-density granulocytes are phenotypically altered in people with long-COVID

In a recent study posted to the bioRxiv* preprint server, researchers characterized low-density granulocyte (LDG) neutrophil (NP) proportion among individuals up to 14 months post-SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection.

28 Oct 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

Rutgers physicians take newer approach in successfully treating a mysterious disease

The prognosis for the sick child, who hadn't responded to standard treatment, was dire. But a team of Rutgers physicians believed there might be hope despite the conventional wisdom against pursuing any further treatment.

27 Oct 2022

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

In a recent study posted to the bioRxiv* preprint server, researchers at Beth Israel Deaconess Medical Center assessed the immunogenicity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.5 bivalent messenger ribonucleic acid (mRNA) vaccine boosters.

27 Oct 2022

An unprecedented list of health-threatening fungi released by the WHO

The WHO fungal priority pathogens list ranks pathogens that pose a serious risk of morbidity and mortality in humans.

27 Oct 2022

New report highlights the health impacts of air pollution in Africa

Nearly all the African continent faces some of the most severe health impacts in the world caused by air pollution, with several countries experiencing some of the highest levels of air pollution in the world, according to a new report published by the U.S.-based research organization Health Effects Institute.

27 Oct 2022

Study sheds light on why some patients respond better than others to immunotherapy

Immunotherapy, a biotherapy that boosts the ability of the immune system to recognize and attack mutant tumor cells, has transformed the treatment landscape for patients battling cancer, which emerges from the progressive accumulation of DNA mutations.

27 Oct 2022

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19.

27 Oct 2022

Does maternal insulin tolerance during pregnancy influence child adiposity?

Researchers explore the association between maternal insulin resistance with fetal fat deposition.

27 Oct 2022

Medical Research News

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

What are the contemporary hazards of cigarette smoking and benefits of quitting smoking by race, ethnicity, and sex among US adults?

E-cigarette use alters respiration but does not impair lung function, according to new findings

The epigenetic alterations of monocytes in severe COVID-19

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

The dynamics of COVID-19 conspiracist ideation

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

ADOS testing not required for ASD diagnosis by developmental-behavioral pediatricians

Low-density granulocytes are phenotypically altered in people with long-COVID

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

Rutgers physicians take newer approach in successfully treating a mysterious disease

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

An unprecedented list of health-threatening fungi released by the WHO

New report highlights the health impacts of air pollution in Africa

Study sheds light on why some patients respond better than others to immunotherapy

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

Does maternal insulin tolerance during pregnancy influence child adiposity?

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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