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Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

The development of the pediatric oral resistome and its role in dental caries

Researchers performed a genomic investigation of oral resistome development, i.e., of genes that confer antimicrobial resistance.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

What is the influence of prenatal second-hand smoke exposure on infant self-regulation?

A new study aimed to analyze an important gap concerning the impact of prenatal SHS exposure on infant self-regulation.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

Uncovering COVID-19's impact on mental health

In a recent study published in the journal BMJ, a team of researchers from Canada and the United Kingdom conducted a systematic review of current research and meta-analysis to compare the symptoms of anxiety and depression and overall mental health among the general population before and after the onset of the coronavirus disease 2019 (COVID-19) pandemic.

14 Mar 2023

Revamping lifestyle can bolster brain health and stave off neurocognitive decline

In a recent article published in the journal Cureus, researchers at Loma Linda University Medical Center and the University of California Irvine reviewed the impact of applying the six pillars of lifestyle medicine — stress management, plant-based nutrition, avoidance of risky substances, physical activity, social connections, and restorative sleep — on neurocognitive decline and dementia.

14 Mar 2023

Is green leaf biomass a viable and sustainable source of protein?

In a recent study published in the journal Nutrients, researchers at North Carolina State University reviewed studies on underutilized sources of plant proteins and discussed strategies to enhance yields, extract nutrients and influence the demand and acceptance of new protein sources, especially green leaf biomass.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Financial disruption during the pandemic adversely influenced children's mental health, shows study

Financial disruption as a result of pandemic containment policies in the United States adversely influenced children's mental health, according to a new study co-led by Weill Cornell Medicine and Columbia University investigators.

13 Mar 2023

The burden of Clostridioides difficile infections in the United States

Researchers review existing data on Clostridioides difficile infections among United States residents.

13 Mar 2023

Hurricane exposure associated with increased mortality among older adults living with dementia

Previous studies of hurricanes have shown general increases in mortality but little has been known about how mortality following hurricane exposure may differ among older adults living with dementia.

13 Mar 2023

Kinetics of successive SARS-CoV-2 infections

Researchers compare viral kinetics of successive SARS-CoV-2 infections.

13 Mar 2023

Consuming low-insulin-stimulating bread significantly reduces body weight

Substituting common insulinogenic bread with bread releasing low levels of inulin could significantly reduce weight among obese individuals.

13 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy.

13 Mar 2023

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

13 Mar 2023

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

A new study by Columbia University researchers suggests that cholesterol-lowering drugs called statins have the potential to reduce heart disease in people with obstructive sleep apnea regardless of the use of CPAP machines during the night.

13 Mar 2023

Medical Research News

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

The development of the pediatric oral resistome and its role in dental caries

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

What is the influence of prenatal second-hand smoke exposure on infant self-regulation?

Oral host responses to SARS-CoV-2 predict progression of COVID-19

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

Uncovering COVID-19's impact on mental health

Revamping lifestyle can bolster brain health and stave off neurocognitive decline

Is green leaf biomass a viable and sustainable source of protein?

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Financial disruption during the pandemic adversely influenced children's mental health, shows study

The burden of Clostridioides difficile infections in the United States

Hurricane exposure associated with increased mortality among older adults living with dementia

Kinetics of successive SARS-CoV-2 infections

Consuming low-insulin-stimulating bread significantly reduces body weight

Hyperinflammation triggers long COVID headaches

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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