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Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Significant improvement in progression-free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which are benign, but locally aggressive and invasive soft tissue tumors.

12 Sep 2022

Study identifies new therapeutic target against lung adenocarcinoma

The TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role in this cancer process was, to date, unknown.

12 Sep 2022

Caregivers in nursing homes experienced high stress levels during the pandemic, study reveals

Caregivers are particularly important during a public health crisis. Now, researchers from Japan have found that caregivers working in nursing homes experienced high levels of psychological distress during the COVID-19 pandemic.

12 Sep 2022

A widening gap found in diabetes-related mortality between urban and rural areas in the USA

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) finds that there is a widening gap in diabetes-related mortality between urban and rural areas in the USA, and that reductions in mortality rates seen predominantly in urban areas have been mainly limited to female and older patients while outcomes in male and younger individuals worsened.

12 Sep 2022

Exercise hormone reduces protein levels linked to Parkinson's disease

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice.

12 Sep 2022

Prenatal cannabis exposure linked with mental health problems that persist into early adolescence

Prenatal cannabis exposure following the middle of the first trimester—generally after five to six weeks of fetal development—is associated with attention, social, and behavioral problems that persist as the affected children progress into early adolescence (11 and 12 years of age), according to new research supported by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

12 Sep 2022

Research could lead to a new therapeutic option for patients with bladder cancer

Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system.

12 Sep 2022

Study reveals two distinct types of obesity with physiological and molecular differences

A team led by Van Andel Institute scientists has identified two distinct types of obesity with physiological and molecular differences that may have lifelong consequences for health, disease and response to medication.

12 Sep 2022

COVID-19 drugs persist through wastewater treatment, may negatively affect aquatic organisms

Certain drugs used to treat COVID-19 patients - including remdesivir, dexamethasone and antibiotics for associated bacterial infections - persist through wastewater treatment and may occur in waterways at levels high enough to negatively affect aquatic organisms, according to a new study led by researchers at Penn State.

12 Sep 2022

What is the risk of SARS-CoV-2 infection among gout patients?

The main outcome of a new study study was to assess the risk of SARS-CoV-2 infection among gout patients.

12 Sep 2022

Review of COVID-19 in children before and after SARS-CoV-2 Delta and Omicron variant emergence

Researchers provided a summary of SARS-CoV-2 infections among children pre- and post-SARS-CoV-2 Delta and Omicron variants of concern (VOCs) emergence.

12 Sep 2022

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

esearchers measured the monkeypox virus-neutralizing antibodies produced by the vaccinia virus vaccine, modified vaccinia virus Ankara vaccine, and monkeypox virus to understand the efficacy of the MVA-Bavarian Nordic vaccine currently being used against monkeypox.

12 Sep 2022

Medical Research News

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Study identifies new therapeutic target against lung adenocarcinoma

Caregivers in nursing homes experienced high stress levels during the pandemic, study reveals

A widening gap found in diabetes-related mortality between urban and rural areas in the USA

Exercise hormone reduces protein levels linked to Parkinson's disease

Prenatal cannabis exposure linked with mental health problems that persist into early adolescence

Research could lead to a new therapeutic option for patients with bladder cancer

Study reveals two distinct types of obesity with physiological and molecular differences

COVID-19 drugs persist through wastewater treatment, may negatively affect aquatic organisms

What is the risk of SARS-CoV-2 infection among gout patients?

Review of COVID-19 in children before and after SARS-CoV-2 Delta and Omicron variant emergence

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

CDC report shows people with monkeypox have higher than expected rates of HIV and STIs

BNT162b2 SARS-CoV-2 vaccinations found to reduce incidence of long COVID symptoms

Study explores link between prenatal stress during COVID-19 pandemic and negative neurodevelopmental outcomes in infants

Role of the transketolase-like 1 gene in the development of the modern human brain

What is the impact of COVID-19 vaccination on erectile function?

UQ researchers receive international funding to combat melanoma in US troops

Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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