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SARS-CoV-2 breakthrough infection in vaccinated individuals induces virus-specific nasal T cells of broad specificity

Long-lasting immune cells that specifically recognize the SARS-CoV-2 virus were found in the noses of people who were infected following vaccination.

12 Sep 2022

$Worldwide hip fracture counts likely to double by 2050, study finds$

Worldwide hip fracture counts likely to double by 2050, study finds

Osteoporotic hip fracture, already a dangerous and debilitating problem for older men and women worldwide, is poised to become a far more severe global public-health issue as the population grows older and frailer, according to a new study led by researchers at the University of Hong Kong.

12 Sep 2022

Mucosal vaccination triggers superior T cell response against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* server, researchers in Singapore and the United States demonstrated that intranasal (I.N.) delivery of a mucosal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination triggered a superior T cell response compared to an equivalent dose of antigen delivered by the subcutaneous (S.C.) route.

12 Sep 2022

Research supports use of FFP2/3 masks for HCWs caring for COVID-19 patients

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom assessed the aerobiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in United Kingdom (UK) hospitals and the impact of aerosol-generating procedures (AGP).

12 Sep 2022

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

The use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer, accelerated their metastatic bone growth, likely because the drugs depleted the mice's intestinal flora and weakened their immune response, according to a new study by researchers at Emory University in Atlanta.

12 Sep 2022

Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

Vaccines that induce mucosal immunity against SARS-CoV-2 are needed

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom studied assessed plasma and nasal antibody (Ab) responses induced after a year of coronavirus disease 2019 (COVID-19)-associated hospitalization and the potential boost by subsequent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations in the United Kingdom (UK).

12 Sep 2022

Study reveals recommended levels of long-term blood sugar to avoid diabetes-related damage

The levels of long-term blood sugar, HbA1c, can be used to accurately determine the risk of a person with type 1 diabetes developing eye- and kidney complications.

12 Sep 2022

Oral anticoagulant drug may be safe, effective in preventing blood clots after urologic cancer surgery

The oral anticoagulant drug apixaban may offer a safer, more effective alternative to standard home heparin injections for patients taking extended prophylaxis (EP) to prevent blood-clot-related complications after surgery, reports a study in The Journal of Urology, an Official Journal of the American Urological Association.

12 Sep 2022

Neoadjuvant NHAs followed by surgery can improve key outcomes in high-risk prostate cancer patients

For high-risk patients with prostate cancer, treatment with novel hormonal agents (NHAs) followed by surgery can reduce the risk of recurrent and progressive cancer, compared to initial treatment with surgery, suggests a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA).

12 Sep 2022

N-dihydrogalactochitosan shows promise as a mucosal vaccine adjuvant against SARS-CoV-2

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated the efficacy of a novel biopolymer, N-dihydrogalactochitosan (GC), as an adjuvant for next-generation mucosal coronavirus disease 2019 (COVID-19) vaccine.

12 Sep 2022

Are pesticides affecting childhood growth in low-income countries?

Researchers assess the risk posed by these chemicals to the developing fetus and child.

12 Sep 2022

Update on SARS-CoV-2 variants detected in animals by USDA

The USDA APHIS has recently updated its web-based dashboard to provide information on all SARS-CoV-2 variants detected in animals

12 Sep 2022

Extreme heat events may increase risk of hypo- and hyperglycemia–related emergencies

The global effects of climate change have been demonstrated to extend beyond the environment to many other areas including human health, particularly with respect to different health conditions.

12 Sep 2022

Long-COVID in adults and Ontario's expected burden

Scientists identify the healthcare requirements for adults with long COVID.

12 Sep 2022

Meal timing may influence mood vulnerability in night workers

Beating the blues with food? A new study adds evidence that meal timing may affect mental health, including levels of depression- and anxiety-related mood.

12 Sep 2022

Regular patterns of activity are important for healthy aging and mental health, study suggests

Older adults who consistently get up early and remain active throughout the day are happier and perform better on cognitive tests than those with irregular activity patterns, according to a new study led by University of Pittsburgh researchers.

12 Sep 2022

Most people prefer fecal immunochemical test rather than a colonoscopy, study says

Three-quarters of people prefer to do a fecal immunochemical test (FIT) rather than a colonoscopy for their regular colorectal cancer screening, according to a new Cedars-Sinai study.

12 Sep 2022

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Obesity can give rise to a variety of health concerns. Nonalcoholic steatohepatitis (NASH) - a type of fatty liver disease that might progress to cancer - is particularly prevalent among obese people.

12 Sep 2022

Study underscores the economic, mental health impacts of COVID-19 on people hit by climate disasters

When the Children's Environmental Health Initiative (CEHI) launched the Texas Flood Registry in April 2018, the goal was to develop a needs assessment focusing on health and housing impacts of the greater Houston area, which was still recovering less than one year after Hurricane Harvey's devastating landfall.

12 Sep 2022

Medical Research News

SARS-CoV-2 breakthrough infection in vaccinated individuals induces virus-specific nasal T cells of broad specificity

Worldwide hip fracture counts likely to double by 2050, study finds

Mucosal vaccination triggers superior T cell response against SARS-CoV-2 variants

Research supports use of FFP2/3 masks for HCWs caring for COVID-19 patients

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

Blocking FNDC5 prevents cancer-induced cachexia in mice

Vaccines that induce mucosal immunity against SARS-CoV-2 are needed

Study reveals recommended levels of long-term blood sugar to avoid diabetes-related damage

Oral anticoagulant drug may be safe, effective in preventing blood clots after urologic cancer surgery

Neoadjuvant NHAs followed by surgery can improve key outcomes in high-risk prostate cancer patients

N-dihydrogalactochitosan shows promise as a mucosal vaccine adjuvant against SARS-CoV-2

Are pesticides affecting childhood growth in low-income countries?

Update on SARS-CoV-2 variants detected in animals by USDA

Extreme heat events may increase risk of hypo- and hyperglycemia–related emergencies

Long-COVID in adults and Ontario's expected burden

Meal timing may influence mood vulnerability in night workers

Regular patterns of activity are important for healthy aging and mental health, study suggests

Most people prefer fecal immunochemical test rather than a colonoscopy, study says

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Study underscores the economic, mental health impacts of COVID-19 on people hit by climate disasters

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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