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Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that annual TB deaths had increased and demonstrating the global need for better access to treatments.

8 Aug 2022

Exercise program improves physical functioning among older adults with chronic kidney disease

This randomized trial recently published in the American Journal of Kidney Diseases (AJKD) found that a 12- month program of in-center aerobic and resistance exercise program improved physical functioning among adults 55 years and older with CKD stages G3b-4 and a high level of medical comorbidities.

8 Aug 2022

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy.

8 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

Should pregnant women be included clinical trials?

The current study reports some of the scientific, ethical, and legal considerations that will support the inclusion of pregnant women in future research.

8 Aug 2022

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

Inflation problem in the U.S. impacts Black families more than many other Americans

A new NPR/Robert Wood Johnson Foundation/Harvard T.H. Chan School of Public Health poll shows that at a time when households across the U.S. widely report experiencing serious problems from inflation, Black Americans are substantially more likely than whites to report they are currently having serious financial problems in this period (55% to 38%).

8 Aug 2022

Yale researchers discover molecular mechanism behind growth of the nervous system

Our nervous system is composed of billions of neurons that speak to each other through their axons and dendrites.

8 Aug 2022

Study explores the relationship between empathy and cyberbullying among early U.S. adolescents

Bullying has been made easier and sometimes more serious by social media, gaming platforms, and other online communications technologies, affecting so many of our schools, families and communities.

8 Aug 2022

COVID-19 vaccination increases antibodies in breast milk significantly

Anti-SARS-CoV-2 antibodies in breast milk capable of neutralizing both an early pandemic SARS-CoV-2 isolate and Omicron variant.

8 Aug 2022

Sperm not affected nine months after COVID-19 mRNA vaccination

A recent study compared the effects of COVID-19 vaccines on male fertility at a median of nine months after receipt of two mRNA vaccine doses.

8 Aug 2022

Lung cancer patients in a screening program who participated in stop smoking study achieve more than 30% abstinence rates

Patients with lung cancer who attended a lung cancer screening event and who then participated in a personalized smoking cessation study achieved smoking abstinence rates of more than 30 percent, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Researchers from Spain have identified an immune expression signature in surgical specimens associated with disease progression for non-complete pathological responders patients treated with neo adjuvant chemo-immunotherapy, which could help the follow-up and therapeutic management of these high-risk patients.

8 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Study compares the nodule management protocols used in NELSON and National Lung Cancer Screening Trial

The protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol used in the National Lung Cancer Screening Trial, particularly for early-stage cancers, according to research reported today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Research highlights the need to increase early detection of lung cancer among younger patients

Younger patients with lung cancer are significantly more likely than older patients to be diagnosed with later stages of disease, illustrating the need to develop strategies to increase the early detection of lung cancer among younger patients who are currently ineligible for lung cancer screening.

8 Aug 2022

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

A large international study of patients with non-small cell lung cancer tumors that are two centimeters or less found that sub lobar surgery was non-inferior to lobectomy, according to results presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

The use of Stereotactic Body Radiotherapy (SBRT) for patients with non-small cell lung cancer can reduce treatment disparities between White and Black patients, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Researchers examine the incidence of second primary lung cancers using National Lung Screening Trial data

Using data from the National Lung Screening Trial, researchers found that the incidence of second primary lung cancer was approximately 4% among the entire cohort of lung cancer patients and was as high as 8% among patients undergoing surgery for stage IA disease.

8 Aug 2022

Medical Research News

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

Exercise program improves physical functioning among older adults with chronic kidney disease

Overnight EEG studies may help inform care for girls with Rett syndrome

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Disruption of the circadian clocks plays a key role in weight gain

Should pregnant women be included clinical trials?

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Inflation problem in the U.S. impacts Black families more than many other Americans

Yale researchers discover molecular mechanism behind growth of the nervous system

Study explores the relationship between empathy and cyberbullying among early U.S. adolescents

COVID-19 vaccination increases antibodies in breast milk significantly

Sperm not affected nine months after COVID-19 mRNA vaccination

Lung cancer patients in a screening program who participated in stop smoking study achieve more than 30% abstinence rates

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Study compares the nodule management protocols used in NELSON and National Lung Cancer Screening Trial

Research highlights the need to increase early detection of lung cancer among younger patients

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

Researchers examine the incidence of second primary lung cancers using National Lung Screening Trial data

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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