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Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

New research from Queen Mary University of London, published in Nature Medicine, has shown that molecular profiling of the diseased joint tissue can significantly impact whether specific drug treatments will work to treat rheumatoid arthritis (RA) patients.

19 May 2022

Study estimates the global RSV disease burden in children under five in 2019

A new study published in The Lancet estimates that RSV-attributable acute lower respiratory infection was responsible for more than 100,000 deaths in children under five across the globe in 2019.

19 May 2022

SARS-CoV-2 Omicron linked to rise in croup in young children

A recent Pediatrics study assesses the causative relationship between SARS-CoV-2 infection and croup or “barking cough” in children.

19 May 2022

Mice study links dietary cholesterol with exacerbation of influenza

New research from the University of Illinois suggests high levels of dietary cholesterol make mice sicker when infected with influenza. The study is the first to link cholesterol in the diet with exacerbation of a viral infection.

19 May 2022

New study reveals the genetic mechanism behind severe staphylococcal infections

A common culprit of skin and respiratory infections, Staphylococcus aureus is highly unpredictable. Between 20 and 30 percent of people carry quiet colonies on their skin and in their nostrils, which seldom cause problems beyond the occasional rash.

19 May 2022

Treating pediatric psychiatric disorders with psychotropic drugs reduces later substance use disorder risk

One half of psychiatric and substance use disorders start by the age of 18; three-quarters by age 24. While these are concerning statistics, a new study from Massachusetts General Hospital finds that treating psychiatric disorders with psychotropic medications in children and adolescents does not increase the risk of developing substance use, misuse, or substance use disorder (SUD).

19 May 2022

Epilepsy drug inhibits the growth of NF1 tumors in mice

People with neurofibromatosis type 1 (NF1) develop tumors on nerves throughout their bodies. These tumors are usually benign - meaning they don't spread to other parts of the body and are not considered life-threatening - but they can still cause serious medical problems such as blindness, especially when they form in the brain and nerves.

19 May 2022

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Researchers analyze the mechanisms by which two SARS-CoV-2 accessory proteins, ORF3a and ORF7a, can downregulate the expression of MHC-I.

19 May 2022

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Scientists discuss how SARS-CoV-2 utilizes myeloid cells to allow for the subsequent viral colonization in the lungs.

19 May 2022

Scientists investigate relevance of COVID-19 vaccine-mediated T cell immunity to SARS-CoV-2 variants

Researchers showed the significance of T cell-based immunity against the SARS-CoV-2 variants exhibiting evasion to antibody-centric immunity.

19 May 2022

Impact of COVID-19 second booster vaccine on all-cause death among older cohorts

Scientists illustrated that the second booster dose of the SARS-CoV-2 vaccinations lowered all-cause death in the long-term care home residents and those aged 80 years or older.

19 May 2022

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

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19 May 2022

Study aims to understand people's various perceptions of sexual consent communication

Teaching the benefits of affirmative sexual consent while also validating anxieties people might experience about consent communication is an important step for improving sexual health and wellbeing, according to a new study.

19 May 2022

Increasing greenery in urban areas may reduce mortality of all causes, study reveals

A new analysis on greenery and mortality found that between 34,000-38,000 deaths could have been reduced with local increases in green vegetation in US metropolitan areas.

19 May 2022

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

The findings of a new pre-clinical study published in The Journal of Neuroscience are helping pave the way toward better understanding, prevention and recovery of neonatal brain injuries.

19 May 2022

New study helps to better understand re-infection rates and correlates of protection for SARS-CoV-2

By uniting research from 8 cohorts across the U.S., a group of researchers has accelerated collection of data integral in answering questions about immune responses needed for long lasting protection from SARS-CoV-2.

19 May 2022

Researchers discover potential treatment approach for advanced uveal melanoma

An international team of researchers led by University College Dublin (UCD) have uncovered a potential treatment approach for advanced uveal melanoma (UM), a type of cancer that effects the eye.

19 May 2022

Black people continue to bear a higher cancer burden even after steady decline in mortality rates

From 1999 to 2019, rates of cancer deaths declined steadily among Black people in the United States. Nevertheless, in 2019, Black people still had considerably higher rates of cancer death than people in other racial and ethnic groups, a large epidemiologic study has found.

19 May 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.

19 May 2022

Medical Research News

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

Study estimates the global RSV disease burden in children under five in 2019

SARS-CoV-2 Omicron linked to rise in croup in young children

Mice study links dietary cholesterol with exacerbation of influenza

New study reveals the genetic mechanism behind severe staphylococcal infections

Treating pediatric psychiatric disorders with psychotropic drugs reduces later substance use disorder risk

Epilepsy drug inhibits the growth of NF1 tumors in mice

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Scientists investigate relevance of COVID-19 vaccine-mediated T cell immunity to SARS-CoV-2 variants

Impact of COVID-19 second booster vaccine on all-cause death among older cohorts

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

Study aims to understand people's various perceptions of sexual consent communication

Increasing greenery in urban areas may reduce mortality of all causes, study reveals

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

New study helps to better understand re-infection rates and correlates of protection for SARS-CoV-2

Researchers discover potential treatment approach for advanced uveal melanoma

Black people continue to bear a higher cancer burden even after steady decline in mortality rates

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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