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Study outlines risk factors for autoimmune hepatitis after liver transplant

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation.

20 May 2022

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a study published in Nature Medicine.

20 May 2022

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Researchers explored whether surface ACE2 carried by EVs can facilitate the entry of SARS-CoV-2 into host cells.

20 May 2022

Important methodology for targeting conserved epitopes of SARS-CoV-2 and an immune-focused approach in pan-sarbeco and universal CoV vaccine design

A new study has focused on designing immunogens associated with the conserved region of the spike protein of SARS-CoV-2.

20 May 2022

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

The link between androgens and COVID-19

A new paper examines the association between androgens and COVID-19, as revealed by the research carried out on this topic throughout the pandemic.

20 May 2022

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

The authors of the current study looked at the potential for an increased risk of parkinsonism following a bout of SARS-CoV-2 infection through accepted post-viral mechanisms.

20 May 2022

Hyperinsulinemic patients with breast cancer may be responsive to metabolism-targeting treatments

Scientists at Yale Cancer Center have found that patients with breast cancer and high levels of insulin in the blood may be responsive to metabolism-targeting treatments, which in turn may improve the effectiveness of subsequent chemotherapy treatments.

20 May 2022

Study tests whether the political climate in each US state and Washington, DC determined the nature of the spread of COVID-19 cases and deaths during 2020

Researchers assessed the association of the spread of coronavirus disease 2019 (COVID-19) with the political climate in the US in 2020.

20 May 2022

Long-term insomnia symptoms associated with poor cognitive functioning in old age

The Helsinki Health Study at the University of Helsinki investigated the development of insomnia symptoms in midlife and their effects on memory, learning ability and concentration after retirement. The follow-up period was 15–17 years.

20 May 2022

Multi-center trial shows promising results for implant-free interatrial shunt device to treat heart failure patients

Results from early clinical evaluation of the Alleviant System to treat heart failure patients with preserved and reduced ejection fraction (HFpEF and HFrEF) was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2022 Scientific Sessions.

20 May 2022

Household contact management could help avert 20% of the multi-drug resistant TB cases in children

One in five multi-drug resistant (MDR) tuberculosis (TB) cases in children under the age of 15 could be averted every year by household contact management, according to a new modeling study published in The Lancet Global Health.

20 May 2022

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Investigators demonstrated S100A9 as an inflammatory biomarker among hospitalized SARS-CoV-2 patients.

20 May 2022

Low-dose apixaban treatment reduces recurrence of venous thromboembolism compared to anticoagulant discontinuation after negative D-dimer

Patients who have suffered from a first episode of unprovoked venous thromboembolism (VTE) have an eight times higher risk of recurrence if they stop treatment after repeated negative D-dimer tests, instead of continuing with low-dose anticoagulant (apixaban).

20 May 2022

‘Watch and wait’ approach may improve outcomes for very frail patients than emergency surgery

New research published in Anaesthesia (a journal of the Association of Anaesthetists) shows that for patients who are very frail, it may be better to adopt a 'watch and wait' approach rather than proceeding to emergency surgery for five common medical emergencies.

20 May 2022

Medical Research News

Study outlines risk factors for autoimmune hepatitis after liver transplant

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Important methodology for targeting conserved epitopes of SARS-CoV-2 and an immune-focused approach in pan-sarbeco and universal CoV vaccine design

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

The link between androgens and COVID-19

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

Hyperinsulinemic patients with breast cancer may be responsive to metabolism-targeting treatments

Study tests whether the political climate in each US state and Washington, DC determined the nature of the spread of COVID-19 cases and deaths during 2020

Long-term insomnia symptoms associated with poor cognitive functioning in old age

Multi-center trial shows promising results for implant-free interatrial shunt device to treat heart failure patients

Household contact management could help avert 20% of the multi-drug resistant TB cases in children

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Low-dose apixaban treatment reduces recurrence of venous thromboembolism compared to anticoagulant discontinuation after negative D-dimer

‘Watch and wait’ approach may improve outcomes for very frail patients than emergency surgery

Existing drug may reduce damage after spinal cord injury, research shows

Serologic response to SARS-CoV-2 may predict COVID-19 severity

Identification of long COVID patients through machine learning

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

Scientists explore mortality among women on hormone replacement therapy early in COVID-19 pandemic

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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