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Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers studied how the mRNA-based BNT162b2 COVID-19 vaccine altered the biochemical composition of glial and glioma brain cells in vitro.

8 Mar 2022

Scientists predict structure of SARS-CoV-2 frameshifting pseudoknot

Researchers recently unveiled the structure of programmed -1 ribosomal frameshifting pseudoknot of SARS-CoV-2.

8 Mar 2022

Study shows anti-itch and pain relief potential of protein in tick saliva

A protein found in tick saliva could be turned into a drug that eases itching and chronic pain in people.

8 Mar 2022

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

Researchers compared the immunogenicity of the reduced and standard doses of the BNT162b2 and mRNA-1273 vaccine in adults immunized with two doses of the CoronaVac vaccine.

8 Mar 2022

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

A recent study reported that monocytosis during the acute phase of coronavirus disease 2019 could forecast anosognosia in long COVID.

8 Mar 2022

Researchers develop scoring tools to determine hospitalization and mortality risk in COVID-19 patients

Researchers conducted a large retrospective study on a cohort of severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 patients, developing and validating a simple and precise scoring tool to risk stratify COVID-19 ambulatory and emergency department patients for subsequent hospitalizations and mortalities.

8 Mar 2022

Recurrent mutations across the SARS-CoV-2 genome associated with long-term infections in immunodeficient patients

Researchers identified recurrent mutations in SARS-CoV-2.

8 Mar 2022

Touch-sensing protein in the gut likely plays a key role in constipation

When we eat food, our gut somehow senses its presence to begin shifting it along our digestive tract, but the question has always been – how?

8 Mar 2022

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

Helping to advance Alzheimer’s disease (AD) research, scientists from The Feinstein Institutes for Medical Research have published two studies supporting the connection of tau – a protein in the brain that forms neurofibrillary tangles that are a hallmark of AD and have been linked to chronic traumatic encephalopathy (CTE) from head trauma – with psychosis in AD.

8 Mar 2022

Study finds Omicron BA.2 responsible for more but less infectious breakthrough infections

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) infections between December 23, 2021, and February 20, 2022, in Qatar to understand how Omicron subvariants, vaccination, and prior infection status impacted these cases.

8 Mar 2022

SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

In a recent study posted to the medRxiv* preprint server, researchers investigated the efficacy of diagnostic tests for identifying severe acute respiratory syndrome coronavirus (SARS-CoV-2) variants of concern (VOCs).

8 Mar 2022

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

In a recent study posted to the medRxiv*preprint server, a team of researchers from Israel developed and validated novel reverse transcriptase - quantitative polymerase chain reaction (RT-qPCR) assays. The new assays enable the rapid and high throughput identification and differentiation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 variants.

8 Mar 2022

Higher SARS-CoV-2 load in morning-collected samples

In a recent study posted to the medRxiv* preprint server, researchers identified that morning-collected nasal and saliva samples yielded better detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially in tests with low to moderate analytical sensitivity.

8 Mar 2022

Bacterial coinfection pervasiveness and antibiotic use in COVID-19 patients

In a recent study posted to the medRxiv* pre-print server, researchers conducted a meta-analysis to determine the bacterial coinfection and antibiotic usage prevalence in coronavirus disease 2019 (COVID-19) patients.

7 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

Glucocorticoid steroids improve muscle performance through distinct, sex-specific molecular pathways

Glucocorticoid steroids improved muscle performance through distinct, sex-specific molecular mechanisms in mice, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

7 Mar 2022

Study identifies two types of brain cells involved in organizing discrete memories

Researchers have identified two types of cells in our brains that are involved in organizing discrete memories based on when they occurred.

7 Mar 2022

Clinical decision support system may help improve cardiovascular health in patients with severe mental illness

In a new study, researchers demonstrated that they can significantly lower cardiovascular risk for patients with severe mental illness (SMI) by using a clinical decision support system that prompts doctors to provide individualized informational handouts about a patient's cardiovascular risk and treatment recommendations.

7 Mar 2022

French study shows COVID vaccine efficacy 94% against severe outcomes

A recent paper published on the medRxiv preprint server utilized data from three national databases containing an abundance of information on Covid-19 screening (SI-DEP), vaccination (VAC-SI), and hospitalizations (SI-VIC) in France to provide additional perspectives on vaccine effectiveness and its evolution over the year 2021 in the French context.

7 Mar 2022

Older adults under severe financial strain more likely to die within six months after heart attack

Older adults who report being under severe financial strain were substantially more likely to die within six months of having a heart attack compared to those with moderate or no financial strain, according to a new study led by University of Maryland School of Medicine researchers.

7 Mar 2022

Medical Research News

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Scientists predict structure of SARS-CoV-2 frameshifting pseudoknot

Study shows anti-itch and pain relief potential of protein in tick saliva

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

Researchers develop scoring tools to determine hospitalization and mortality risk in COVID-19 patients

Recurrent mutations across the SARS-CoV-2 genome associated with long-term infections in immunodeficient patients

Touch-sensing protein in the gut likely plays a key role in constipation

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

Study finds Omicron BA.2 responsible for more but less infectious breakthrough infections

SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

Higher SARS-CoV-2 load in morning-collected samples

Bacterial coinfection pervasiveness and antibiotic use in COVID-19 patients

How have human organoids been used in research to study SARS-CoV-2?

Glucocorticoid steroids improve muscle performance through distinct, sex-specific molecular pathways

Study identifies two types of brain cells involved in organizing discrete memories

Clinical decision support system may help improve cardiovascular health in patients with severe mental illness

French study shows COVID vaccine efficacy 94% against severe outcomes

Older adults under severe financial strain more likely to die within six months after heart attack

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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