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Brain pulsations driving glymphatic function differ in narcolepsy patients and healthy individuals

A hormone produced by the brain, orexin, may play a central role in the functioning of the brain’s glymphatic system, which clears waste, according to a new study from the University of Oulu.

1 Sep 2025

Glutamate receptors found to drive pediatric brain tumor development

The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors.

1 Sep 2025

Dual antiplatelet therapy after heart bypass surgery offers no added benefit over aspirin alone

Dual antiplatelet therapy after heart bypass surgery is not more effective than aspirin alone - and it increases the risk of excessive bleeding. This has now been shown in a study of 2,201 patients at 22 Nordic heart surgery units.

1 Sep 2025

Landmark study maps mutational landscape of triple-negative breast cancer in African American women

Triple-negative breast cancer (TNBC), the deadliest breast cancer subtype, disproportionately affects African American women – but until now, they were underrepresented in genomic studies aimed at identifying the genetic mutations driving the disease.

1 Sep 2025

Select groups of myocardial infarction patients benefit from Helicobacter pylori screening

Not all acute myocardial infarction patients should be offered routine screening for the stomach ulcer bacterium Helicobacter pylori.

1 Sep 2025

Heart failure hospitalization occurs earlier in Black and Hispanic adults than white patients

Black adults in the U.S. are first hospitalized for heart failure nearly 14 years earlier than white adults, reports a Northwestern Medicine study that analyzed data from more than 42,000 patients across hundreds of hospitals nationwide.

1 Sep 2025

Androgen deprivation therapy lowers satisfaction after penile prosthesis surgery

Prostate cancer is the most common malignancy among men, with over 160,000 new cases diagnosed annually in the United States.

1 Sep 2025

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

For decades, testosterone has been recognized as the primary driver of male reproductive development and secondary sex characteristics.

1 Sep 2025

Review maps Toxoplasma hotspots: Half in Eastern Europe infected by age 44

Researchers systematically reviewed and modeled Toxoplasma gondii seroprevalence across 25 European countries. The study found striking regional differences, with highest infection levels in eastern and western Europe and lowest in the UK and northern regions.

1 Sep 2025

Can honey protect your brain? Study reviews its potential against Alzheimer's

This review examined 27 preclinical studies on honey and Alzheimer’s disease, showing honey’s bioactive compounds counter oxidative stress, inflammation, and amyloid buildup. Despite promising lab results, no human trials exist, underscoring the need for clinical research.

1 Sep 2025

Why metformin could protect the brain by rewiring mitochondria

Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its potential as a therapy for multiple sclerosis.

1 Sep 2025

Breastfeeding at six months boosts children’s IQ and academic skills into adolescence

Breastfeeding at six months was linked to higher IQ, better reading and math skills, and improved conversational abilities in children, according to the ALSPAC study. The findings, based on 42 significant outcomes, highlight long-term cognitive advantages but stop short of proving causality.

1 Sep 2025

How a Mediterranean diet helps women manage menopausal symptoms

A cross-sectional study of 149 postmenopausal women found that greater adherence to a modified Mediterranean diet was linked to lower odds of moderate to severe hot flashes and sexual symptoms. While psychological and physical domains showed no significant association, the results support further evaluation of diet as a non-hormonal strategy for menopausal care.

1 Sep 2025

Cancer-related nerve injury triggers inflammation and immunotherapy resistance

Cancer cells can break down the protective covers around nerves, causing nerve injury that triggers chronic inflammation leading to immune exhaustion and eventual resistance to immunotherapy, according to new research from The University of Texas MD Anderson Cancer Center.

1 Sep 2025

Genomic clues uncover early origins of multiple myeloma

A new study maps out the timeline of DNA damage for multiple myeloma, the second most common blood cancer.

1 Sep 2025

Gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

1 Sep 2025

Study provides evidence for a causal genetic link between prostate cancer and urothelial carcinoma

Prostate cancer is among the most common cancers in men and a leading cause of cancer-related deaths. With improved detection and therapies, survival rates have risen, but this progress comes with a new concern: the risk of secondary primary malignancies.

1 Sep 2025

$New hypothesis links internal fat biology to heart failure with preserved ejection fraction$

New hypothesis links internal fat biology to heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFpEF) appears to develop as a result of changes in the biology of a person's internal fat tissue, according to the Adipokine Hypothesis, a new way of understanding how fat may impact the heart.

1 Sep 2025

Drug-coated devices not associated with improved outcomes in patients with peripheral artery disease

Drug-coated stents and balloons were not associated with reduced risk of amputation or improved quality of life compared with uncoated devices in two trials in peripheral artery disease (PAD), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Tailored risk-based treatment does not improve outcomes in atrial fibrillation

An individually tailored multidimensional risk-based treatment strategy was not associated with improvements in clinical outcomes compared with usual guideline-based care in patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

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Medical Research News

Brain pulsations driving glymphatic function differ in narcolepsy patients and healthy individuals

Glutamate receptors found to drive pediatric brain tumor development

Dual antiplatelet therapy after heart bypass surgery offers no added benefit over aspirin alone

Landmark study maps mutational landscape of triple-negative breast cancer in African American women

Select groups of myocardial infarction patients benefit from Helicobacter pylori screening

Heart failure hospitalization occurs earlier in Black and Hispanic adults than white patients

Androgen deprivation therapy lowers satisfaction after penile prosthesis surgery

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

Review maps Toxoplasma hotspots: Half in Eastern Europe infected by age 44

Can honey protect your brain? Study reviews its potential against Alzheimer's

Why metformin could protect the brain by rewiring mitochondria

Breastfeeding at six months boosts children’s IQ and academic skills into adolescence

How a Mediterranean diet helps women manage menopausal symptoms

Cancer-related nerve injury triggers inflammation and immunotherapy resistance

Genomic clues uncover early origins of multiple myeloma

Gait retraining reduces pain and slows knee damage in osteoarthritis

Study provides evidence for a causal genetic link between prostate cancer and urothelial carcinoma

New hypothesis links internal fat biology to heart failure with preserved ejection fraction

Drug-coated devices not associated with improved outcomes in patients with peripheral artery disease

Tailored risk-based treatment does not improve outcomes in atrial fibrillation

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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