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CRATERs identified as key sites for T cell-mediated tumor destruction

Like the surface of the moon, new research published today in Cell finds the existence of craters on the surface of melanoma cells that serve as immune hubs, becoming major sites for tumor killing. These craters could serve as good markers for immunotherapy success.

17 Oct 2025

Supportive signals during pregnancy ease return-to-work transition for women

Returning to work after maternity leave can leave new mothers wrestling with guilt – feeling they can't fully win at work or home.

17 Oct 2025

Researchers achieve proof of concept for generating eggs from somatic cells

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos.

17 Oct 2025

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs).

17 Oct 2025

How task engagement reshapes the brain’s auditory processing

When we are engaged in a task, our brain's auditory system changes how it works. One of the main auditory centers of the brain, auditory cortex, is filled with neural activity that is not sound driven – rather, this activity times the task, each neuron ticking at a different moment during task performance.

17 Oct 2025

Research reveals how immune cells orchestrate the release of toxic granules

When immune cells strike, precision is everything. New research reveals how natural killer and T cells orchestrate the release of toxic granules – microscopic packages that destroy virus-infected or cancerous cells.

17 Oct 2025

Scientists discover why a powerful leukemia drug fails in most patients

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients – and found a potential way to overcome that resistance.

17 Oct 2025

People's heart health unlikely to be affected by some industrially processed hard fats

Two types of industrially processed hard fats, widely used in everyday foods such as bakery products, margarines and spreads, are unlikely to affect heart health when consumed in levels achievable in most people's diets.

17 Oct 2025

Preexisting hyperlipidemia in pregnancy linked to obstetric and early heart risks

Preexisting hyperlipidemia in pregnancy is associated with heightened risks of obstetric complications and early cardiovascular events in the first five-years postpartum, according to a new study being presented at ACC's Cardio-Obstetrics Essentials: Team-Based Management of Cardiovascular Disease and Pregnancy conference.

17 Oct 2025

Runx1 overexpression triggers early intervertebral disc degeneration

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, "Runx1 overexpression induces early onset of intervertebral disc degeneration."

17 Oct 2025

Restoring pleiotrophin shows promise for improving brain function in Down syndrome

Faulty brain circuits seen in Down syndrome may be caused by the lack of a particular molecule essential for the development and function of the nervous system, new research suggests.

17 Oct 2025

Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1

A class of antivirals called Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1 (HSV-1), the common infection behind oral herpes, according to new research published in Antiviral Research on July 25.

17 Oct 2025

How age influences the perception of ambiguous facial expressions

Do you find it easy to perceive people you meet as happy and positive? Or are you vigilant and look for signs of dissatisfaction and anger in their facial expressions?

17 Oct 2025

Study: Hidden fat inside the abdomen and liver may damage arteries

A new study led by researchers at McMaster University reveals that hidden fat deep inside the abdomen and liver may quietly damage arteries, even in people who appear healthy.

17 Oct 2025

Understanding post-traumatic vasospasm as a hidden complication of traumatic brain injury

A new review published in the Journal of Intensive Medicine on 25 July, 2025 and led by Dr. Alice Jacquens and Dr. Clara Perrault from Pitié Salpêtrière Hospital, Paris, France, sheds light on an under-recognized complication of traumatic brain injury (TBI): post-traumatic vasospasm (PTV).

17 Oct 2025