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Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

A new preprint examines the extent of protection offered by T cell responses to primary vaccination and/or natural infection with the virus.

11 Jan 2022

COVID-19 symptoms found to vary in different immune contexts

In a new study, researchers studied the kinetics of host response to SARS-CoV-2 infection in a Syrian hamster model, tracking disease pathology, viral loads, antibody responses, and inflammatory cytokine production in multiple organs.

11 Jan 2022

Study reveals an increasing proportion of women giving birth at 40+

An increasing proportion of women aged 40 and over in Sweden and Denmark are giving birth. Nevertheless, over a recent 10-year period, the need for assisted reproduction for women over 40 in Scandinavia has doubled, a study led by University of Gothenburg researchers shows.

11 Jan 2022

Analyzing the evolution of SARS-CoV-2 RNA polymerase in humans

In a new study, researchers examined the impact of mutations on the structural thermodynamic stability (structural stability) of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) through free energy computation.

11 Jan 2022

Low birth weight among IVF babies unlikely to be driven by the reproductive technology

Children conceived through medically assisted reproduction are more likely to be born premature and are at greater risk of being born small than naturally conceived babies, according to new research published today by the UCL Centre for Longitudinal Studies in collaboration with the University of Utah.

11 Jan 2022

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

A new preprint describes a single-step molecular diagnostic test for the presence of SARS-CoV-2 infection caused by the Omicron variant that is behind the unprecedented rise in cases over the last few weeks.

11 Jan 2022

Evaluating effectiveness of the COVID-19 mRNA-1273 vaccine against Omicron and Delta variants

Researchers recently assessed vaccine effectiveness against Omicron and Delta variant-induced infection as well as hospitalization, including among immunocompromised individuals.

11 Jan 2022

Study finds heterologous vaccine booster evokes robust immunity to SARS-CoV-2 Omicron variant

The current study examines the role of heterologous vaccination, an area that lacks much clarity.

11 Jan 2022

The effect of COVID-19 on routine immunizations for vaccine-preventable diseases

A new study has focussed on determining the impact of COVID-19 associated interferences with different recovery scenarios for ten vaccine-preventable diseases.

11 Jan 2022

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

A team of researchers recently analyzed differential protein glyco-isoform distributions of symptomatic and asymptomatic coronavirus disease 2019 patients.

11 Jan 2022

Dynamics of infectious diseases and restrictions on the size of social gatherings

A new study has been published that used epidemiological theory to elucidate the association between gathering size and general disease dynamics.

11 Jan 2022

Development and validation of 2-gene host-based COVID-19 diagnostic classifiers

A group of researchers from Biohub has been attempting to create a more accurate method for PCR testing.

11 Jan 2022

Real-world effectiveness of three COVID-19 vaccines

Researchers from IQVIA Real-World Solutions have investigated how effective these vaccines are against severe disease.

11 Jan 2022

Secondhand nicotine vaping at home may increase risk of bronchitic symptoms in young adults

Secondhand exposure at home to the nicotine vapour from e-cigarettes is linked to a heightened risk of bronchitic symptoms and shortness of breath among young adults, finds research published online in the respiratory journal Thorax.

11 Jan 2022

Psychotropic drugs are commonly used by patients with heart disease, study shows

Antidepressants and other psychiatric medications are associated with an almost doubled risk of premature death in patients with heart conditions, according to research published today in the European Journal of Cardiovascular Nursing, a journal of the European Society of Cardiology (ESC).

11 Jan 2022

What are the predictors of inpatient COVID-19 mortality rates?

A new study, conducted by a multidisciplinary team of researchers from Suffolk University, Boston, Massachusetts, examined the relationship between baseline staffing levels of registered nurses (RNs), hospitalists, emergency medicine physicians, and intensivists (staff) and hospital-level COVID-19 mortality rates. The research builds on and extends earlier research that examined a subset of hospital-level characteristics over a shorter time period.

11 Jan 2022

Long-term exposure to air pollutants may increase the incidence of COVID-19

Long term exposure to ambient air pollution may heighten the risk of COVID-19 infection, suggests research published online in the journal Occupational & Environmental Medicine.

11 Jan 2022

Latest tools for COVID-19 Omicron variant research

AMSBIO has announced new additions to its portfolio of tools for COVID-19 research - two monoclonal antibodies that recognize the Spike RBD (B.1.1.529, Omicron Variant) protein and neutralizes its interaction with ACE2.

From AMS Biotechnology 11 Jan 2022

An algorithmic method to identify epidemic waves of COVID-19

In this research paper, a team of scientists from various institutions across the UK and Poland provides contributions aimed at resolving this issue. First, the authors clarify the multiple ways researchers use the word 'epidemic wave.' Their technique divides epidemic time series (of confirmed cases and deaths) into non-overlapping 'observed waves.'

11 Jan 2022

Optimal monoclonal antibodies against SARS-CoV-2 variants

Researchers screen different monoclonal antibodies to identify an optimal mAb with higher binding affinity to the receptor-binding domain of SARS-CoV-2.

10 Jan 2022

Medical Research News

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

COVID-19 symptoms found to vary in different immune contexts

Study reveals an increasing proportion of women giving birth at 40+

Analyzing the evolution of SARS-CoV-2 RNA polymerase in humans

Low birth weight among IVF babies unlikely to be driven by the reproductive technology

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

Evaluating effectiveness of the COVID-19 mRNA-1273 vaccine against Omicron and Delta variants

Study finds heterologous vaccine booster evokes robust immunity to SARS-CoV-2 Omicron variant

The effect of COVID-19 on routine immunizations for vaccine-preventable diseases

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

Dynamics of infectious diseases and restrictions on the size of social gatherings

Development and validation of 2-gene host-based COVID-19 diagnostic classifiers

Real-world effectiveness of three COVID-19 vaccines

Secondhand nicotine vaping at home may increase risk of bronchitic symptoms in young adults

Psychotropic drugs are commonly used by patients with heart disease, study shows

What are the predictors of inpatient COVID-19 mortality rates?

Long-term exposure to air pollutants may increase the incidence of COVID-19

Latest tools for COVID-19 Omicron variant research

An algorithmic method to identify epidemic waves of COVID-19

Optimal monoclonal antibodies against SARS-CoV-2 variants

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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