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Using deductive reasoning based on particle physics' principles in aging research

Aging-US published "Applying deductive reasoning and the principles of particle physics to aging research" which reported that aging research currently lacks a common conceptual framework, and one challenge in establishing it is the fact that aging is a highly complex process.

7 Nov 2021

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Immune checkpoint inhibitors (ICIs) have transformed cancer care by unleashing T-cells to fight tumors, but they can cause serious cardiotoxicities including myocarditis. ICI-induced myocarditis represents a new clinical syndrome because of the novelty and considerable usage of ICIs.

7 Nov 2021

Middlemen take home almost 53% of the net proceeds from insulin sales, finds study

Despite its discovery nearly 100 years ago, insulin's list price has been going up, not down, with trade secrets and other protections preventing researchers from pinpointing who is receiving profits from its sale.

7 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

Deletion of ABI3 gene in the brain may increase risk of developing Alzheimer’s disease

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them.

7 Nov 2021

Maternal exposure to flame retardants linked with ASD-relevant behavioral traits in offspring

Polybrominated diphenyl ethers, or PBDEs, are a class of fire-retardant chemicals that are ubiquitous. They are found on upholstery, carpets, curtains, electronics, and even infant products.

7 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

Results of high-impact clinical trials could affect kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online at ASN Kidney Week 2021 November 4–November 7.

7 Nov 2021

Prescription drug for multiple sclerosis improves memory in Alzheimer's mouse model

Losing memory is a hallmark of Alzheimer's, a symptom of the disease that depletes a patient's quality of life. Improving memory and slowing cognitive changes caused by the disease is an ongoing challenge for researchers seeking to develop novel therapies.

7 Nov 2021

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Scientists at the Francis Crick Institute have found how the immune system triggers an 'emergency' dendritic cell response during infection, with dendritic cells at the site of infection being reinforced by new cells which travel from the bone marrow.

6 Nov 2021

Neural synchrony found to be predictive for favorable outcome after coma

Coma patients in ICU, e.g. after cardiac arrest, have been targeted in research projects for many years. One of the key questions is how to predict the outcome after coma. Current approaches are often based on qualitative assessment of electroencephalogram (EEG) patterns.

6 Nov 2021

Study identifies RNA molecule that suppresses prostate tumors

Many patients with prostate cancer are treated with drugs that lower or block hormones that fuel tumor growth. While the drugs are effective for a time, most patients eventually develop resistance to these therapies.

6 Nov 2021

Study opens a window for new therapeutic approaches to ovarian cancer

A Ludwig Cancer Research study has uncovered a cellular interaction that is essential to the ability of the immune system's cytotoxic T lymphocytes to destroy ovarian tumors and shown that its engagement could help determine the efficacy of checkpoint blockade immunotherapy in a variety of cancers.

6 Nov 2021

Medical Research News

Using deductive reasoning based on particle physics' principles in aging research

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Middlemen take home almost 53% of the net proceeds from insulin sales, finds study

Therapeutics that target ceramides may help treat cardiometabolic disease

Deletion of ABI3 gene in the brain may increase risk of developing Alzheimer’s disease

Maternal exposure to flame retardants linked with ASD-relevant behavioral traits in offspring

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Results of high-impact clinical trials could affect kidney-related medical care

Prescription drug for multiple sclerosis improves memory in Alzheimer's mouse model

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Neural synchrony found to be predictive for favorable outcome after coma

Study identifies RNA molecule that suppresses prostate tumors

Study opens a window for new therapeutic approaches to ovarian cancer

Key link between chronic stress and cancer discovered

Experts gain insights into pathomechanisms of dilated cardiomyopathy

Study identifies serotonin as a possible trigger of flare-ups in Crohn's disease

Researchers use suction method to deliver SARS-CoV-2 DNA vaccine in lab tests

School-based screening can help tackle depression in youth

Study uncovers a process in cells that may limit infectivity of SARS-CoV-2

Electronic dating violence increases in preadolescence but curves as teens reach adulthood

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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