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Could the marine compound plitidepsin promote recovery from moderate COVID-19?

A new paper by an international team of researchers describes experimental evidence of the antiviral efficacy of a marine compound called plitidepsin against SARS-CoV-2. The findings show that plitidepsin inhibits SARS-CoV at low concentrations, as observed by a thousand-fold reduction in genomic RNA and viral titers in cells exposed to the virus in culture when treated.

27 May 2021

Nanobody inhalation found to be effective against COVID-19 in hamsters

In a recent paper, researchers describe an aerosolized nanobody formulation that was found to effectively block SARS-CoV-2 in Syrian hamsters.

27 May 2021

Waters Introduces the SARS-CoV-2 LC-MS Kit (RUO) to Advance Clinical Research of Infectious Diseases

Waters Corporation today introduced a new RUO LC-MS test method to advance critical infectious disease research.

From Waters Corporation 27 May 2021

New DNA COVID-19 vaccine proven effective in mice

A new study has shown that a new DNA-based COVID-19 vaccine successfully induced immunization against SARS-CoV-2 in mice and hamsters.

27 May 2021

OCD linked to higher stroke risk in later life

New findings indicate that the risk of developing ischemic strokes is increased in people with obsessive-compulsive disorder (OCD).

27 May 2021

Study shows CoronaVac to have high seroconversion rate after 40 days

Researchers from the Federal University of Paraná, Brazil, looked into the seroconversion rate after vaccination with the CoronaVac. Using immunoassays, they measured the immunoglobulins (IgG) for anti-nucleocapsid protein (anti-N) antibodies and anti-spike-1 (anti-S1) protein antibodies.

27 May 2021

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

COVID-19 was initially described as lung inflammation, or pneumonia, in older adults. However, we now know that SARS-CoV-2 infections can cause a wide range of symptoms in people of all ages, ranging from no symptoms at all to systemic inflammation and even death.

27 May 2021

New porous biomaterial could help in bone repair

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new biomaterial made entirely from discarded bullfrog skin and fish scales that could help in bone repair.

27 May 2021

Caffeine can boost energy and mood but does not fight sleep deprivation

Rough night of sleep? Relying on caffeine to get you through the day isn't always the answer, says a new study from Michigan State University.

27 May 2021

Oligo DNA improves differentiation of skeletal muscles exacerbated by diabetes

Skeletal muscle is the largest organ in the body that accounts for 30 to 40% of body weight and is responsible for multiple functions such as energy metabolism and heat production.

27 May 2021

Toxic man-made chemicals that end up in the environment highlight regulation challenges

Researchers at the University of New Hampshire have conducted two of the first studies in New England to collectively show that toxic man-made chemicals called PFAS (per-and polyfluoroalkyl substances), found in everything from rugs to product packaging, end up in the environment differently after being processed through wastewater treatment facilities--making it more challenging to set acceptable screening levels.

27 May 2021

Researchers discover new brain circuit that may help fight obesity

Like a good story, feeding has a beginning, a middle and an end. It begins with appetite prompting the search for food, continues with eating the food and it ends when satiation hits and the consumption of food is stopped.

27 May 2021

New plasmofluidic chip could speed up diagnosis during current and future pandemics

Reverse transcription-polymerase chain reaction (RT-PCR) has been the gold standard for diagnosis during the COVID-19 pandemic.

27 May 2021

Protein-RNA interactions in SARS-CoV-2-infected cells reveal key regulators of infection

Researchers in the UK, including the University of Oxford and Glasgow, as well as the University of Heidelberg, published their analysis of protein-RNA interactions in SARS-CoV-2 and the subsequent significance in the journal Molecular Cell. This research could help to uncover novel antiviral strategies for COVID-19 due to a broader understanding of how the virus works.

27 May 2021

Proteomics technology shows how exercise improves the efficiency of muscle energy production

Mitochondria are the cell's power plants and produce the majority of a cell's energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation.

27 May 2021

EU project to investigate impact and consequences of micro and nanoplastics on human health

PLASTICHEAL project will develop new methodologies and will provide reliable scientific evidence for regulators to set the knowledge basis for adequate risk assessment. The results will draw a variety of experimental human models and measuring potential health effects under short and long-term conditions.

27 May 2021

Scientists develop new resources to combat cancer, advance cutting-edge genomics research

University of Virginia School of Medicine scientists have developed important new resources that will aid the battle against cancer and advance cutting-edge genomics research.

27 May 2021

Adults with schizophrenia have increased risk of dying from suicide

Adults with schizophrenia have an elevated risk of dying from suicide. Yet there's only limited understanding of when and why people with schizophrenia die of suicide --in part because research studies have looked at relatively small groups of patients.

27 May 2021

Researchers identify new way to improve the diagnosis of fetal heart defects

UC San Francisco researchers have found a way to double doctors' accuracy in detecting the vast majority of complex fetal heart defects in utero - when interventions could either correct them or greatly improve a child's chance of survival - by combining routine ultrasound imaging with machine-learning computer tools.

27 May 2021

House design can decrease the force of malaria infection

There is growing evidence that house design can decrease the force of malaria infection. The world's most deadly assassin is Africa's malaria mosquito: Anopheles gambiae.

27 May 2021