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Scientists identify an antiviral metabolite as a potential serum biomarker for SARS-CoV-2 infection

Scientists from the UK have recently identified an antiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine as a potential serum biomarker to diagnose active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the medRxiv* preprint server while awaiting peer review.

27 Jul 2021

Study could lead to blood-based diagnostic test for schizophrenia

Scientists at Sanford Burnham Prebys have discovered how levels of a protein could be used in the future as a blood-based diagnostic aid for schizophrenia.

27 Jul 2021

SARS-CoV-2 interacts with unusual RNA structures in human cells

The study, published in the journal Nucleic Acids Research, demonstrated that G4 ligands, the chemical that binds with G4s, prevent this interaction. The results could pave the way for developing inhibitors of these interactions as potential antiviral compounds.

26 Jul 2021

One dose of mRNA vaccine reduced COVID risk for at least four months in health care workers

A new study compared the efficacy of mRNA vaccines against the original strain of the SARS-CoV-2 and SARS-CoV-2 VoCs among HCWs in Quebec after receiving their first and second doses.

26 Jul 2021

Budesonide’s antiviral effect against SARS-CoV-2

A new study examines the in vitro antiviral effect of pure budesonide and Pulmicort® against the SARS-CoV-2 WT and two VoCs.

26 Jul 2021

A novel interferon-γ release assay for detection of SARS-CoV-2 specific T-cell response

A new study evaluates a commercially available IFN‐γ release assay (IGRA) to determine T-cell responses targeted against SARS-CoV-2.

26 Jul 2021

Child's toothbrushing habits linked to mother's mental health

A mother's mental health may play a larger role in a child's toothbrushing habits than previously thought.

26 Jul 2021

CDC study on efficacy of mRNA vaccines against symptomatic COVID-19

A new study posted to the medRxiv* preprint server derives measures of substantial efficacy for these vaccines in preventing mild to moderate COVID-19 from a group of outpatients with and without a history of vaccination.

26 Jul 2021

‘Social prescribing’ may help lonely older adults to avoid harmful sedatives and painkillers

Lonely, older adults are nearly twice as likely to use opioids to ease pain and two-and-a-half times more likely to use sedatives and anti-anxiety medications, putting themselves at risk for drug dependency, impaired attention, falls and other accidents, and further cognitive impairment, according to a study by researchers at UC San Francisco.

26 Jul 2021

Study reveals safety of second mRNA COVID-19 vaccine dose after allergic reactions to first dose

In a multi-hospital analysis of individuals who experienced an allergic reaction to their first mRNA COVID-19 vaccine dose, all patients who went on to receive a second dose tolerated it without complications.

26 Jul 2021

New statistical framework could help determine the 'true prevalence' of COVID-19 pandemic

Government officials and policymakers have tried to use numbers to grasp COVID-19's impact. Figures like the number of hospitalizations or deaths reflect part of this burden. Each datapoint tells only part of the story.

26 Jul 2021

Sick leave eligibility rules in the U.S. widen racial inequalities in the labor market, finds study

Paid sick leave is one of the most powerful tools for preventing the spread of COVID-19 and other infectious diseases and ensuring all workers can access treatment - yet tens of millions of workers across the U.S. lack coverage.

26 Jul 2021

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Frontotemporal dementias are a group of fatal and debilitating brain disorders for which there are no cures.

26 Jul 2021

Experts present new research to improve care for head and neck cancers at AHNS 2021

As the international community of experts in head-and-neck cancers gathered virtually last week to share new ideas and treatment strategies at the just-ended American Head & Neck Society (AHNS) 10th International Conference on Head and Neck Cancer, Roswell Park Comprehensive Cancer Center teams are presented new research on both the basic science supporting new treatments as well as opportunities to improve the early and accurate diagnosis of thyroid cancer and other head/neck malignancies.

26 Jul 2021

Air quality improvement linked with reduced risk of dementia

Improving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today at the Alzheimer's Association International Conference 2021 in Denver and virtually.

26 Jul 2021

Excessive body fat can increase the risk of dementia

It's the global epidemic that affects two in every five adults, but as obesity continues to expand waistlines worldwide, researchers at the University of South Australia are warning that harmful body fat can also increase the risk of dementia and stroke.

26 Jul 2021

More popular type of antihypertensive drugs causes slightly more side effects

Two types of drugs that are recommended as a first treatment for patients with high blood pressure were found equally effective in improving cardiovascular outcomes, but the more popular type causes slightly more side effects, finds a multinational observational study led by researchers at Columbia University Vagelos College of Physicians and Surgeons.

26 Jul 2021

Two types of blood pressure drugs provide equal benefits, but side effects differ

People who are just beginning treatment for high blood pressure can benefit equally from two different classes of medicine - angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) - yet ARBs may be less likely to cause medication side effects, according to an analysis of real-world data published today in Hypertension, an American Heart Association journal.

26 Jul 2021

How SARS-CoV-2 vaccination symptoms differ from early COVID-19 symptoms

A new study published on the preprint server medRxiv* presents an analysis of the differences between recorded vaccination side effects vs. early COVID-19 symptoms. The researchers focused on four vaccines, namely, Pfizer-BioNTech (PB) mRNA (BNT162b2) vaccine, based on messenger ribonucleic acid encoding the viral spike protein; the Moderna mRNA (mRNA-1273) vaccine; the Oxford-AstraZeneca (O-AZ) adenovirus-vectored vaccine; and the Janssen adenovirus-vectored Ad26.COV2.S).

26 Jul 2021

SARS-CoV-2 antibodies in breast milk: Study

A new study published on the medRxiv* preprint server explores the presence of immunoglobulin (Ig) antibodies IgA and IgG against SARS-CoV-2 in breast milk secreted by women with confirmed infection. The scientists also delineated the specific antigens targeted by the antibodies.

26 Jul 2021

Medical Research News

Scientists identify an antiviral metabolite as a potential serum biomarker for SARS-CoV-2 infection

Study could lead to blood-based diagnostic test for schizophrenia

SARS-CoV-2 interacts with unusual RNA structures in human cells

One dose of mRNA vaccine reduced COVID risk for at least four months in health care workers

Budesonide’s antiviral effect against SARS-CoV-2

A novel interferon-γ release assay for detection of SARS-CoV-2 specific T-cell response

Child's toothbrushing habits linked to mother's mental health

CDC study on efficacy of mRNA vaccines against symptomatic COVID-19

‘Social prescribing’ may help lonely older adults to avoid harmful sedatives and painkillers

Study reveals safety of second mRNA COVID-19 vaccine dose after allergic reactions to first dose

New statistical framework could help determine the 'true prevalence' of COVID-19 pandemic

Sick leave eligibility rules in the U.S. widen racial inequalities in the labor market, finds study

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Experts present new research to improve care for head and neck cancers at AHNS 2021

Air quality improvement linked with reduced risk of dementia

Excessive body fat can increase the risk of dementia

More popular type of antihypertensive drugs causes slightly more side effects

Two types of blood pressure drugs provide equal benefits, but side effects differ

How SARS-CoV-2 vaccination symptoms differ from early COVID-19 symptoms

SARS-CoV-2 antibodies in breast milk: Study

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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