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Can prior human seasonal coronavirus antibody response patterns predict SARS-CoV-2 inhibition?

A new study, recently released as a preprint on the medRxiv* server, reports the intriguing finding that the cross-neutralizing antibodies elicited by human seasonal coronaviruses (sCoVs) show varying ability to prevent binding between the SARS-CoV-2 spike antigen and its cognate receptor, the angiotensin-converting enzyme 2 (ACE2).

22 Jul 2021

Pfizer vaccine and isolation independently associated with reduced household transmission of SARS-CoV-2

Israel was among the leading proponents of COVID-19 vaccination as the way out of the current worldwide restrictions on social and economic interactions and activity. A new study, recently released as a preprint on the medRxiv* server, reports on the effects of the large-scale vaccination campaigns carried out in this country, relating to successful control of SARS-CoV-2 spread within households.

22 Jul 2021

Study: Omega-3 levels in blood erythrocytes are good mortality risk predictors

Levels of omega-3 fatty acids in the blood are as good a predictor of mortality from any cause as smoking, according to a study involving the Hospital del Mar Medical Research Institute (IMIM), in collaboration with The Fatty Acid Research Institute in the United States and several universities in the United States and Canada.

22 Jul 2021

Scientists restore memory in aging mice

Scientists at Cambridge and Leeds have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of treatments to prevent memory loss in people as they age.

22 Jul 2021

Antibiotics may be the new weapon to fight against melanoma

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumours in mice. Their findings were published in the Journal of Experimental Medicine.

22 Jul 2021

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Research led by Queen Mary University of London provides new insight into the mechanisms that lead to uncontrolled inflammation in COVID-19 patients.

22 Jul 2021

Epstein-Barr virus reactivation may play a role in long COVID and severe COVID-19 cases

Two recently published studies available on the National Institutes of Health website indicate Epstein-Barr virus (EBV) reactivation may play a role both in the development of long COVID symptoms, as well as severe COVID-19 cases.

22 Jul 2021

Study reveals calcium's role in directing blood flow in the brain

Unlike the rest of the body, there is not enough real estate in the brain for stored energy. Instead, the brain relies on the hundreds of miles of blood vessels within it to supply fresh energy via the blood. Yet, how the brain expresses a need for more energy during increased activity and then directs its blood supply to specific hot spots was, until now, poorly understood.

22 Jul 2021

Emerging SARS-CoV-2 mutations L452R & Y453F evade cellular immunity

The study, published in the journal Cell Host & Microbe, also showed emerging mutations L452R and Y453F in the SARS-CoV-2 spike receptor-binding motif evade (HLA) A24-restricted cellular immunity. Meanwhile, the L452R enhances spike stability, viral fusogenicity, and viral infectivity. Hence, the findings suggest that HLA-restricted cellular immunity potentially affects the evolution of viral phenotypes.

22 Jul 2021

Use of topical fluorides for caries prevention in primary teeth

Alexandria, Va., USA - Parach Sirivichayakul, Mahidol University, Bangkok, Thailand, presented the poster "Preventing Approximal Caries in Primary Teeth With Topical Fluorides" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.

22 Jul 2021

Study finds link between residential proximity to oil and gas drilling and lower birthweights in infants

A new study from Oregon State University found that infants born within 3 kilometers of oil and natural gas drilling facilities in Texas had slightly lower birthweights than those born before drilling began in their vicinity.

22 Jul 2021

Survey provides insights into 'pure awareness' state experienced by meditators

In the context of meditation practice, meditators can experience a state of "pure awareness" or "pure consciousness", in which they perceive consciousness itself.

22 Jul 2021

Scientist explore conserved RNA elements as potential targets for anti-SARS-CoV-2 drugs

The study, published in the journal Angewandte Chemie International Edition, identified many small molecules that bind to certain parts of the SARS-CoV-2 genome that are less likely altered by mutations using dedicated substance libraries. The scientists derived key functional units and groups in ligands for effective and safe targeting of SARS-CoV-2 RNA.

22 Jul 2021

Researchers elucidate the mechanisms that facilitate accurate identification of moving images

An international collaboration elucidates the mechanisms that facilitate accurate identification of moving images. The findings have been published in Nature Communications.

22 Jul 2021

Study: Older adults are just as capable as younger people of learning behaviors that benefit others

Older adults may be slower to learn actions and behaviors that benefit themselves, but new research shows they are just as capable as younger people of learning behaviors that benefit others.

22 Jul 2021

Two-dose regimen of mRNA vaccines provides protection against Alpha and Beta variants in France

Over the past six months, the World Health Organization has categorized four SARS-CoV-2 variants as being "of concern" because they are more transmissible or may escape the immune response.

22 Jul 2021

Professional rugby participation may be linked with structural changes in the brain

Participation in elite adult rugby may be associated with changes in brain structure.

22 Jul 2021

SARS-CoV-2 proteins manipulate autophagy

The ongoing coronavirus pandemic (COVID-19) has claimed more than 4.1 million lives worldwide. This pandemic is caused by a novel single-stranded RNA virus, namely, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that was first reported in 2019 in Wuhan, China. The rapid spread of this virus is attributed to its high infectiousness and its ability to escape and counteract host immune responses, e.g., autophagy.

22 Jul 2021

Experts call for immediate action to ensure physical activity is built into everyday lives

Not enough progress has been made to address physical inactivity worldwide, with adolescents and people living with disabilities (PLWD) among the least likely populations to have the support needed to meet the World Health Organization (WHO)'s physical activity guidelines.

22 Jul 2021

SARS-CoV-2 genomic surveillance identifies intricacies of stabilizing vs. destabilizing mutations

Some of these variants, known as variants of concern (VoC), have a much higher rate of transmission and increased mortality than the original SARS-CoV-2 strain. Therefore, it is imperative to assess the efficacy of the available vaccines against the circulating SARS-CoV-2 strains. In addition, tracking the continuously evolving genetic variants is also vital to prevent future outbreaks.

22 Jul 2021

Medical Research News

Can prior human seasonal coronavirus antibody response patterns predict SARS-CoV-2 inhibition?

Pfizer vaccine and isolation independently associated with reduced household transmission of SARS-CoV-2

Study: Omega-3 levels in blood erythrocytes are good mortality risk predictors

Scientists restore memory in aging mice

Antibiotics may be the new weapon to fight against melanoma

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Epstein-Barr virus reactivation may play a role in long COVID and severe COVID-19 cases

Study reveals calcium's role in directing blood flow in the brain

Emerging SARS-CoV-2 mutations L452R & Y453F evade cellular immunity

Use of topical fluorides for caries prevention in primary teeth

Study finds link between residential proximity to oil and gas drilling and lower birthweights in infants

Survey provides insights into 'pure awareness' state experienced by meditators

Scientist explore conserved RNA elements as potential targets for anti-SARS-CoV-2 drugs

Researchers elucidate the mechanisms that facilitate accurate identification of moving images

Study: Older adults are just as capable as younger people of learning behaviors that benefit others

Two-dose regimen of mRNA vaccines provides protection against Alpha and Beta variants in France

Professional rugby participation may be linked with structural changes in the brain

SARS-CoV-2 proteins manipulate autophagy

Experts call for immediate action to ensure physical activity is built into everyday lives

SARS-CoV-2 genomic surveillance identifies intricacies of stabilizing vs. destabilizing mutations

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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