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Urolithin A shows promise to slow progression of Duchenne Muscle Dystrophy

Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today.

7 Apr 2021

Hopkins Medicine endocrinologist publishes first clinical practice review on diabetes management

New medicines for people who have diabetes seem to pop up all the time. Drugs that help the body break down carbohydrates, drugs that increase excretion of glucose in the urine, drugs that help muscles respond to insulin and drugs that stimulate the pancreas to produce it - the list of pharmaceutical options to treat diabetes gets longer and longer.

7 Apr 2021

Memory and executive function symptoms are valuable for predicting CTE pathology, suggests study

Diagnosing Chronic Traumatic Encephalopathy (CTE) during life is crucial for developing therapies and for determining how common the disease is among individuals exposed to repetitive head impacts from contact sports, military service and physical violence.

7 Apr 2021

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines.

7 Apr 2021

Pandemic's mitigation efforts may have contributed to drop in clinical trial completion rates

Social distancing and lockdowns may have reduced the spread of COVID-19, but researchers from Penn State College of Medicine also report those actions may have affected clinical researchers' ability to finish trials.

7 Apr 2021

Study offers localized treatment direction for a cause of Crohn's disease

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects.

7 Apr 2021

Manual workers are twice as likely to develop ALS, study finds

ALS is a progressive neurological disease that attacks the nerves that interact with the body's muscles. The disease typically leads to complete paralysis of the body, robbing patients of their ability to walk, speak, eat and breathe.

7 Apr 2021

A proprioceptive control strategy for management of low back pain

Low back pain in the elderly is the result of poor “proprioception,” or the body’s ability to perceive its own position in space, caused by a deterioration of sensory receptors in their muscles called proprioceptors.

7 Apr 2021

SlowMo therapy helps treat paranoid thoughts in people experiencing psychosis

A new clinical trial from King's College London's Institute of Psychiatry, Psychology, & Neuroscience, in collaboration with Oxford University, Oxford Health NHS Foundation Trust, Sussex University, and Sussex Partnership NHS Foundation Trust has established an innovative therapy as an effective means of treating paranoid thoughts in people experiencing psychosis.

7 Apr 2021

$15.7 million NIMH grant to renew UC Davis Conte Center studying the origins of mental illness

Discovering how infections during pregnancy, such as COVID-19 and influenza, can lead to psychiatric illness and developmental disorders in offspring years later, and how to detect, prevent or treat these disorders, is the subject of a $15.7 million grant from the National Institute of Mental Health to the Conte Center at the University of California, Davis.

7 Apr 2021

USF wins $44.4 million NIH grant to test whether computerized brain training can prevent dementia

The National Institutes of Health has awarded the University of South Florida total expected funds of $44.4 million over the next five years to study whether computerized brain training exercises can reduce the risk of mild cognitive impairment (MCI), and dementias like Alzheimer's disease, in older adults.

7 Apr 2021

Researchers identify novel SARS-CoV-2 variant unregistered on genomic sequence databases

A team of scientists from the University of California Santa Cruz, USA, recently identified a novel variant (B.1.x) of SARS-CoV-2 that might be circulating in at least 20 US states and six countries globally.

7 Apr 2021

Novel polyclonal antibody XAV-19 efficiently neutralizes UK and South African SARS-CoV-2 variants

A promising new study reports on the high neutralizing efficacy of a polyclonal swine antibody against SARS-CoV-2, the pathogen responsible for the novel COVID-19. By demonstrating the ability of this antibody to neutralize all currently circulating viral variants, the study suggests that it is ideal for development as a new and very effective therapy for COVID-19.

7 Apr 2021

Which SARS-CoV-2 spike mutants can evade T cell immunity?

A new study reports the capability of a new variant of the virus to escape specific cellular immunity, while possessing a higher binding affinity to the host cell binding receptor, the angiotensin-converting enzyme 2 (ACE2).

7 Apr 2021

Enhanced neutralization of SARS-CoV-2 South African variant with heterologous adjuvant vaccine candidate

A new study describes the use of a single dose of vaccine based on the viral protein called the receptor-binding domain (RBD) to elicit powerful neutralizing activity against both the Wuhan strain and the most concerning VOC called the South African (SA) strain.

7 Apr 2021

Study indicates an amyloid link between melanoma and Parkinson’s disease

On the surface, Parkinson's disease - a neurodegenerative disorder - and melanoma - a type of skin cancer - do not appear to have much in common.

7 Apr 2021

COVID-19 pandemic highlights the key role of biodiversity collections

Events such as the COVID-19 pandemic have highlighted the crucial role played by biodiversity collections in enabling rapid responses to crises and in facilitating ongoing research across numerous fields.

7 Apr 2021

Computer-based approach helps diagnose neurological disorders based on motor impairment

The way we move says a lot about the state of our brain. While normal motor behavior points to a healthy brain function, deviations can indicate impairments owing to neurological diseases.

7 Apr 2021

South African and Brazilian SARS-CoV-2 variants can evade antibodies from therapies, vaccines, and infection

Researchers at the Infection Biology Unit, German Primate Center, and the Georg-August-University Göttingen in Germany have found that the B.1.351 and P.1 SARS-CoV-2 variants have the potential to evade therapeutic antibodies or antibodies induced by natural infection or vaccination.

7 Apr 2021

World Health Day 2021: The humanitarians building a fairer world

In commemoration of World Health Day 2021, News-Medical interviews the International Medical Corps on how they are helping to achieve a fairer and healthier world.

7 Apr 2021

Medical Research News

Urolithin A shows promise to slow progression of Duchenne Muscle Dystrophy

Hopkins Medicine endocrinologist publishes first clinical practice review on diabetes management

Memory and executive function symptoms are valuable for predicting CTE pathology, suggests study

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

Pandemic's mitigation efforts may have contributed to drop in clinical trial completion rates

Study offers localized treatment direction for a cause of Crohn's disease

Manual workers are twice as likely to develop ALS, study finds

A proprioceptive control strategy for management of low back pain

SlowMo therapy helps treat paranoid thoughts in people experiencing psychosis

$15.7 million NIMH grant to renew UC Davis Conte Center studying the origins of mental illness

USF wins $44.4 million NIH grant to test whether computerized brain training can prevent dementia

Researchers identify novel SARS-CoV-2 variant unregistered on genomic sequence databases

Novel polyclonal antibody XAV-19 efficiently neutralizes UK and South African SARS-CoV-2 variants

Which SARS-CoV-2 spike mutants can evade T cell immunity?

Enhanced neutralization of SARS-CoV-2 South African variant with heterologous adjuvant vaccine candidate

Study indicates an amyloid link between melanoma and Parkinson’s disease

COVID-19 pandemic highlights the key role of biodiversity collections

Computer-based approach helps diagnose neurological disorders based on motor impairment

South African and Brazilian SARS-CoV-2 variants can evade antibodies from therapies, vaccines, and infection

World Health Day 2021: The humanitarians building a fairer world

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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