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SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Researchers have measured the antibody levels and types in hospitalized coronavirus disease 2019 (COVID-19) patients with different disease severity. Their results suggest gut immune pathways could play a role in reducing virus-based inflammation and recovery.

22 Dec 2020

Trinity team uncovers mutations linked with early onset dementia

Scientists at Trinity College Dublin today announced a significant advance in our understanding of an early onset form of dementia that may also progress our understanding of conditions such as Alzheimer's disease.

22 Dec 2020

What are the potential benefits of SARS-CoV-2 antigen-based rapid diagnostic tests?

A team of researchers from the Johns Hopkins University, USA; Imperial College London, UK; and Foundation for Innovative New Diagnostics, Switzerland, recently compared the effectiveness of Ag-RDT, NAAT, and clinical judgment alone in the diagnosis of COVID-19 in symptomatic patients.

22 Dec 2020

Large proportion of UK population hesitant over COVID-19 vaccine

Researcher Dr. Alex de Figueiredo from the London School of Hygiene and Tropical Medicine has conducted a study showing that a significant proportion of people in the UK will probably be reluctant to receive a vaccine to protect against coronavirus disease 2019 (COVID-19).

22 Dec 2020

Large-scale study set up in UK to assess possibility of SARS-CoV-2 re-infection among healthcare workers

Researchers from Public Health England are conducting a large-scale prospective longitudinal study to determine whether healthcare workers who have previously developed coronavirus disease 2019 (COVID-19) are immune to reinfection with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Dec 2020

Nanoplastics affect composition and diversity of human intestinal microbiome

We live in a world invaded by plastic. Its role as a chemically stable, versatile and multi-purpose fostered its massive use, which has finally translated into our current situation of planetary pollution.

22 Dec 2020

Study shows how specific Salmonella bacteria evolved to cause bloodstream infection

University of Liverpool scientists have exploited the combined power of genomics and epidemiology to understand how a type of Salmonella bacteria evolved to kill hundreds of thousands of immunocompromised people in Africa.

22 Dec 2020

Study examines how obesity affected postpartum hemorrhage outcomes at a tertiary care center

Postpartum hemorrhage, or excessive bleeding after delivery, is still one of the leading causes of severe maternal injury and death in the United States. And the rise in obesity among pregnant women has been linked to increased rates of this potentially serious, largely preventable obstetric complication.

22 Dec 2020

Clinical psychologist evaluates the dangers of race-based norms in cognitive testing

A UCSF clinical psychologist has taken aim at the National Football League (NFL) for "race norming" black players diagnosed with dementia, a practice that is depriving them of the monetary awards allocated to former footballers with neurodegenerative disorders.

22 Dec 2020

Self-collected nasal swabs may provide a reliable alternative to nasopharyngeal swabs

Under certain conditions, antigen testing using self-collected swabs from the anterior nose may constitute a reliable alternative to antigen testing using nasopharyngeal swabs collected by health professionals.

22 Dec 2020

Study shows how sodium ions drive glutamate transport in the central nervous system

Scientists from the MIPT Research Center for Molecular Mechanisms of Aging and Age-Related Diseases have joined forces with their colleagues from Forschungszentrum Jülich, Germany, and uncovered how sodium ions drive glutamate transport in the central nervous system.

22 Dec 2020

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers of the "Cell Biology and Physiology-LABRET" group of the University of Malaga (UMA), together with the Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), have described a new genetic skeletal disorder based on a precision medicine strategy.

22 Dec 2020

Novel 3D maps show how genes interact in several types of immune cells

The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.

22 Dec 2020

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Immune inflammatory mediators are critical in pathology, transplantation, and regenerative medicine, scientists report in The American Journal of Pathology

22 Dec 2020

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

An infant's odd case of rare encephalitis not typically found in children led researchers to discover never before seen genetic mutations and a more accurate technique to examine the IRAK4 gene responsible for innate immunity.

22 Dec 2020

Study sheds new light on immune system interactions with cancer

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

21 Dec 2020

Researchers have a promising lead on COVID-19 treatment

By taking a lesson from prostate cancer, researchers now have a promising lead on treatment for COVID-19. Two proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, M.D., Ph.D. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers. They also knew that TMPRSS2 was regulated by the androgen receptor.

21 Dec 2020

Study depicts previously unknown molecular mechanism underlying healthy brain development

A research team led by Michael Fox, a professor at the Fralin Biomedical Research Institute at VTC, has identified the type of brain cell that produces collagen 19, a protein that is crucial for the formation of inhibitory circuits in the brain.

21 Dec 2020

Reston virus causes severe respiratory disease in piglets

Reston ebolavirus (RESTV) should be considered a livestock pathogen with potential to affect other mammals, including people, according to National Institutes of Health scientists.

21 Dec 2020

Nocturnal respiratory rate of heart patients can help predict the success of ICD treatment

onditions causing arrhythmia are among the most common cardiac conditions. A study headed by Prof. Georg Schmidt of the Technical University of Munich has demonstrated for the first time that the nocturnal respiratory rate can help with an important prediction: It is an indicator of whether a defibrillator will help to extend the life of patients with arrhythmia.

21 Dec 2020

Medical Research News

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Trinity team uncovers mutations linked with early onset dementia

What are the potential benefits of SARS-CoV-2 antigen-based rapid diagnostic tests?

Large proportion of UK population hesitant over COVID-19 vaccine

Large-scale study set up in UK to assess possibility of SARS-CoV-2 re-infection among healthcare workers

Nanoplastics affect composition and diversity of human intestinal microbiome

Study shows how specific Salmonella bacteria evolved to cause bloodstream infection

Study examines how obesity affected postpartum hemorrhage outcomes at a tertiary care center

Clinical psychologist evaluates the dangers of race-based norms in cognitive testing

Self-collected nasal swabs may provide a reliable alternative to nasopharyngeal swabs

Study shows how sodium ions drive glutamate transport in the central nervous system

Researchers use massive sequencing methods to identify rare genetic bone disorder

Novel 3D maps show how genes interact in several types of immune cells

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

Study sheds new light on immune system interactions with cancer

Researchers have a promising lead on COVID-19 treatment

Study depicts previously unknown molecular mechanism underlying healthy brain development

Reston virus causes severe respiratory disease in piglets

Nocturnal respiratory rate of heart patients can help predict the success of ICD treatment

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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