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Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

15 Feb 2021

Controlling cardiovascular disease risk factors early in life may protect against later dementia

Employing cardiovascular disease prevention strategies in mid-life may delay or stop the brain alterations that can lead to dementia later in life, according to a study in the Journal of the American College of Cardiology.

15 Feb 2021

Cancer research efforts hampered by lack of stable funding and insufficient protected time

Translating laboratory discoveries to clinical care for patients with cancer is a difficult process. Much of the effort is carried by researchers who are also trained as physicians, especially a subgroup known as clinician investigators.

15 Feb 2021

Existing heart failure drug may be effective in treating postural orthostatic tachycardia syndrome

In a new study out of University of California San Diego School of Medicine, researchers found a drug used for heart failure improves symptoms associated with postural orthostatic tachycardia syndrome, otherwise known as POTS.

15 Feb 2021

Study finds link between brain metabolism, cardiovascular risk, and atherosclerosis

The links between cardiovascular disease and cognitive impairment begin years before the appearance of the first clinical symptoms of either condition.

15 Feb 2021

Researchers report a new SARS-CoV-2 variant of concern in Uganda

An interdisciplinary research team from Uganda and the UK report the emergence and spread of a new SARS-CoV-2 variant of the A lineage with multiple protein changes throughout the viral genome.

15 Feb 2021

Researchers observe rapid increase of SARS-CoV-2 antibodies in plasma over pandemic's course

Researchers found that neutralizing antibodies against SARS-CoV-2 can increase over time. They observed that samples taken from convalescent plasma in September 2020 would likely have high enough values by July 2021 to protect immunodeficient patients who receive intravenous immunoglobulins as part of their treatment.

15 Feb 2021

Scientists discover new immunotherapy target for malignant brain tumors

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system.

15 Feb 2021

SARS-CoV-2 South Africa and Brazil variants show resistance to therapeutic antibodies

Scientists from Germany have determined the efficacy of currently used therapeutics in treating newer variants of SARS-CoV-2, including the UK, South Africa, and Brazil variants. Their findings reveal that both B.1.351 and B.1.1.248 variants are able to escape humoral immune responses induced by therapeutic antibodies, vaccinations, or natural SARS-CoV-2 infection.

15 Feb 2021

Benjamin L. Ebert receives Sjöberg Prize for breakthrough research on blood cancer

Benjamin L. Ebert, USA, receives this year's Sjöberg Prize, worth one million US dollars, for his research into how lenalidomide works as a treatment for blood cancer.

15 Feb 2021

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

A new study by researchers at the University of Connecticut Health Center, USA, reports the crucial nature of the pathogen pattern recognition receptor (PRRs), especially the two RLRs, retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5), in triggering host cell immune responses within the cell. The RLRs are viral RNA sensors.

15 Feb 2021

Study: Gut microbiota impacts the progression of brain lesions after stroke

Stroke-induced inflammation is both a blessing and a curse. Some of the inflammatory processes help heal the damaged brain after treatment, but others severely damage neurons and whole-body function.

15 Feb 2021

Study shows CPR is the “gold standard” technique against other alternatives

A technique frequently portrayed in dramatic resuscitation scenes in television and film is among several alternative methods to CPR that have shown no benefit in saving lives in a review by University of Warwick researchers.

15 Feb 2021

Researchers develop protocols for rapid serological surveys of SARS-CoV-2 infection

A new study by researchers from Emory and Yale Universities in the USA discusses a design for quickly launching serological surveys to assess the prevalence of this infection in a given population.

15 Feb 2021

LifeArc supports the GenOMICC COVID-19 Study

Medical research charity, LifeArc, announces today that it is providing £5 million funding to support the work of the GenOMICC COVID-19 Study, led by the GenOMICC consortium in partnership with Genomics England.

15 Feb 2021

Immunosuppressive therapies may be linked to severe COVID-19 in those with multiple sclerosis

A new study examines the associations between immunosuppressive disease-modifying therapies (DMTs) used in MS with adverse outcomes in an international cohort of patients with MS COVID-19.

15 Feb 2021

Study finds certain plasma microRNAs as diagnostic biomarkers for mild traumatic brain injury

Certain plasma microRNAs could serve as diagnostic biomarkers in mild traumatic brain injury, a new study from the University of Eastern Finland shows.

15 Feb 2021

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

In a new study, researchers discuss the use of simultaneous sequencing of both human and viral genes to better understand SARS-CoV-2's infection pathway.

15 Feb 2021

Commuters are breathing in high levels of chemicals that increase cancer risk

A new study finds that California's commuters are likely inhaling chemicals at levels that increase the risk for cancer and birth defects.

15 Feb 2021

Gay men more likely to face stigma and avoidant prejudice from heterosexual peers

Gay men are more likely than lesbian women to face stigma and avoidant prejudice from their heterosexual peers due to the sound of their voice, a new study in the British Journal of Social Psychology reports.

15 Feb 2021

Medical Research News

Study suggests a new way to personalize anti-CTLA-4 therapy for cancers

Controlling cardiovascular disease risk factors early in life may protect against later dementia

Cancer research efforts hampered by lack of stable funding and insufficient protected time

Existing heart failure drug may be effective in treating postural orthostatic tachycardia syndrome

Study finds link between brain metabolism, cardiovascular risk, and atherosclerosis

Researchers report a new SARS-CoV-2 variant of concern in Uganda

Researchers observe rapid increase of SARS-CoV-2 antibodies in plasma over pandemic's course

Scientists discover new immunotherapy target for malignant brain tumors

SARS-CoV-2 South Africa and Brazil variants show resistance to therapeutic antibodies

Benjamin L. Ebert receives Sjöberg Prize for breakthrough research on blood cancer

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

Study: Gut microbiota impacts the progression of brain lesions after stroke

Study shows CPR is the “gold standard” technique against other alternatives

Researchers develop protocols for rapid serological surveys of SARS-CoV-2 infection

LifeArc supports the GenOMICC COVID-19 Study

Immunosuppressive therapies may be linked to severe COVID-19 in those with multiple sclerosis

Study finds certain plasma microRNAs as diagnostic biomarkers for mild traumatic brain injury

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

Commuters are breathing in high levels of chemicals that increase cancer risk

Gay men more likely to face stigma and avoidant prejudice from heterosexual peers

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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