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Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Clonal hematopoiesis can confer a health benefit in allogeneic transplants

Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer.

7 Dec 2020

Researchers identify potential drug combination to treat uveal melanoma

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have identified a potential drug combination to treat uveal melanoma, a type of eye cancer.

7 Dec 2020

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

B-cell lymphoma and leukemias (BCL) are a diverse set of malignancies. While the genomic landscape of many BCL subtypes has been described, genomic ancestry has rarely been explored.

6 Dec 2020

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial.

6 Dec 2020

COVID-19 pandemic underscores racial inequalities in US: a Michigan case study

A team of researchers has explored how the coronavirus disease 2019 (COVID-19) pandemic has disproportionately affected Black Americans.

6 Dec 2020

Crucial monitoring tools effective for assessment of patients with COVID-19

A combined research team from the Universities of Portsmouth and Bournemouth and Portsmouth Hospitals University NHS Trust has shown that an assessment score used to measure a patient's severity of illness can be applied to patients with Covid-19 without modification.

5 Dec 2020

New federal grant boosts clinical trial access for Louisiana's children

A new $2.1 million federal grant will give more of Louisiana's children access to cutting-edge health research while training young scientists in pediatric research.

5 Dec 2020

Blood type not associated with the effects of plant-based diet

A study published in the Journal of the Academy of Nutrition and Dietetics by researchers with the Physicians Committee for Responsible Medicine--a nonprofit of 12,000 doctors--debunks the "blood type diet" by finding that blood type was not associated with the effects of a plant-based diet on body weight, body fat, plasma lipid concentrations, or glycemic control.

5 Dec 2020

Los Robles enrolls first patient in landmark trial for treatment of chronic subdural hematoma

Los Robles Health System is leading the way in neurovascular clinical trials enrolling the first patient in the nation in STEM, the Squid trial for the treatment of chronic subdural hematoma (cSDH).

5 Dec 2020

Researchers urge policymakers to prioritize people with diabetes for COVID-19 vaccination

Vanderbilt University Medical Center researchers have discovered individuals with type 1 and type 2 diabetes infected with COVID-19 are three times more likely to have a severe illness or require hospitalization compared with people without diabetes.

5 Dec 2020

New study examines the increase in virtual doctor visits

When the COVID-19 lockdowns began in mid-March 2020, hospitals and clinics faced a new challenge: How could they continue to provide care to those who could not leave their homes?

5 Dec 2020

Study identifies frequency, risk factors of acute kidney injury in children with diabetic ketoacidosis

Researchers from a consortium of hospitals including Children's Hospital of Philadelphia (CHOP) have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury.

5 Dec 2020

Black patients hospitalized with COVID-19 less likely to have severe illness, die compared to Whites

While multiple research studies show that Black and Hispanic patients are more likely to test positive for COVID-19, a team of investigators at NYU Langone Health has found that once hospitalized, Black patients (after controlling for other serious health conditions and neighborhood income) were less likely to have severe illness, die, or be discharged to hospice compared to White patients.

5 Dec 2020

Donor stem cell transplant can improve survival rates for older patients with MDS, study shows

A new clinical trial offers the most compelling evidence to date that a donor stem cell transplant can improve survival rates for older patients with higher-risk myelodysplastic syndrome (MDS), Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology Annual Meeting.

5 Dec 2020

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

An analysis of lung tissues from patients with different types of pulmonary fibrosis - including cases triggered by COVID-19 - has revealed a promising molecular target to ameliorate the chronic and irreversible disease.

5 Dec 2020

Traveling in passenger cars with windows open is the safest way to prevent COVID-19 transmission

A new series of computational fluid dynamics simulations suggests that, for two people who must travel together in the same passenger car, the safest way to prevent possible transmission of COVID-19 in such a risky, enclosed environment is to do so with all four windows down and the passenger seated as far as possible from the driver, in the rear seat on the opposite side.

5 Dec 2020

Mysterious particle found in the blood of people with sepsis

Researchers at La Jolla Institute for Immunology have found that people with sepsis have never-before-seen particles in their blood.

5 Dec 2020

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

Since the novel coronavirus emerged at the end of last year, scientists around the world -- including Beth Israel Deaconess Medical Center (BIDMC) immunologist Dan Barouch, MD, PhD -- have been developing vaccines to protect against COVID-19 and to put an end to the global pandemic.

5 Dec 2020

Medical Research News

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Clonal hematopoiesis can confer a health benefit in allogeneic transplants

Researchers identify potential drug combination to treat uveal melanoma

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

COVID-19 pandemic underscores racial inequalities in US: a Michigan case study

Crucial monitoring tools effective for assessment of patients with COVID-19

New federal grant boosts clinical trial access for Louisiana's children

Blood type not associated with the effects of plant-based diet

Los Robles enrolls first patient in landmark trial for treatment of chronic subdural hematoma

Researchers urge policymakers to prioritize people with diabetes for COVID-19 vaccination

New study examines the increase in virtual doctor visits

Study identifies frequency, risk factors of acute kidney injury in children with diabetic ketoacidosis

Black patients hospitalized with COVID-19 less likely to have severe illness, die compared to Whites

Donor stem cell transplant can improve survival rates for older patients with MDS, study shows

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

Traveling in passenger cars with windows open is the safest way to prevent COVID-19 transmission

Mysterious particle found in the blood of people with sepsis

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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