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Study sheds light on possible lung damage caused by COVID-19 virus

The study, published today in The Lancet's eBioMedicine, by King's College London in collaboration with University of Trieste and the International Centre for Genetic Engineering and Biology in Italy, shows the unique characteristics to the SARS-CoV-2 virus and may explain why patients suffer from 'long COVID'.

4 Nov 2020

Discoverey of four SARS-CoV-2 Mpro inhibitors, boceprevir, calpain inhibitors II and XII and GC-376

A team of scientists from the United States has recently revealed that small molecule inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease exhibit potent antiviral activity. These inhibitors show better efficacy when used in combination with antiviral medicine Remdesivir. The study is currently available on the bioRxiv* preprint server.

3 Nov 2020

Most SARS-CoV-2-infected individuals develop durable B cell-mediated immunity

Researchers from the Johns Hopkins University and The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA, investigated the durability of B cell immunity following SARS-CoV-2 infection and recovery in their recent work published on the preprint server medRxiv.

3 Nov 2020

Evidence of robust and persistent antibodies against SARS-CoV-2

A team of researchers from the Icahn School of Medicine at Mount Sinai, New York, have worked in collaboration to try and answer one of the most baffling questions surrounding the coronavirus disease 19 (COVID-19) pandemic: do antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) last after a primary infection?

3 Nov 2020

SARS-CoV-2 mutations becoming more contagious

A team of researchers working with Scott Wesley Long from Houston Methodist Hospital and colleagues from Texas, New York, and Illinois studied the patterns of genetic mutations of SARS CoV-2 and its impact on the second wave of infections worldwide.

3 Nov 2020

SARS-CoV-2 T-cell immunity is retained for at least six months

Now, a new study published on the preprint server bioRxiv shows that functional SARS-CoV-2-specific T-cell responses are retained for six months following infection. However, the strength of this response depends on the clinical features of the primary infection.

3 Nov 2020

United States is falling behind in the health care of older population, study shows

An international study led by UCLA Fielding School of Public Health researchers has determined that the United States is far from the most effective healthcare provider for those 50 and older among 23 countries, ranging from Austria to the United States.

3 Nov 2020

SARS-CoV-2 attack rates among household contacts higher than among non-household contacts

Now, a team of researchers at the National Centre for Infectious Diseases in Singapore aimed to determine the transmission risk factors of SARS-CoV-2 among household and non-household contacts.

3 Nov 2020

Study finds a subset of quick COVID-19 healers and antibody 'sustainers'

One of the pressing questions about COVID-19 remains: How long does immunity last? One key indicator of immunity is the presence of virus-specific antibodies.

3 Nov 2020

AI speech processing framework detects inaudible COVID-19 cough

Now, a team of researchers at the Massachusetts Institute of Technology (MIT) has found that asymptomatic people may differ from those who are healthy in the way they cough. The differences are inaudible to the human ear but can be detected by artificial intelligence (AI).

3 Nov 2020

Researchers track the flight trajectory of airborne cough droplets

The ongoing COVID-19 pandemic has led many researchers to study airborne droplet transmission in different conditions and environments. The latest studies are starting to incorporate important aspects of fluid physics to deepen our understanding of viral transmission.

3 Nov 2020

Study shows active surveillance to be safe for African American men with low-risk prostate cancer

Previous studies have shown that African American men are 2.4 times as likely to die from prostate cancer compared to non-Hispanic white men.

3 Nov 2020

16 new lineages of SARS-CoV-2 emerge in South Africa despite lockdown

Published in a recent medRxiv* paper, researchers from South Africa, the United Kingdom, and Brazil found that these mutations in SARS-CoV-2 lineages are localized to South Africa. These unique strains, not found elsewhere in the world, are thought to have contributed around 42% to the country's total infection rate.

3 Nov 2020

Researchers to explore the role of gut microbes in childhood celiac disease

Boston College Assistant Professor of Biology Emrah Altindis has received a three-year, $300,000-grant from the G. Harold and Leila Y. Mathers Foundation for research into childhood celiac disease.

3 Nov 2020

Adaptive evolution of human coronaviruses may necessitate frequent reformulation of vaccines

Researchers from the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center, USA, have revealed that adaptive evolution in the antigenic regions facilitates seasonal coronaviruses to escape the host immune responses and to cause recurrent infections.

3 Nov 2020

Some of the main osteoporosis treatments could have a protective effect against COVID-19

Some of the principal treatments for osteoporosis, denosumab, zoledronate and calcium, could have a protective effect against COVID-19 in patients who take them, specifically a 30 to 40% reduction in the rate of infection, according to the results of a joint study by Hospital del Mar, the Hospital del Mar Medical Research Institute (IMIM), Pompeu Fabra University and the Pere Virgili Health Park.

3 Nov 2020

Study identifies structural, functional brain differences in people with occupational blast exposure

Military and law enforcement personnel with extensive occupational blast exposure had statistically significant differences in brain imaging measures compared to nonexposed control personnel.

3 Nov 2020

Rapid generation of divergent synthetic antibodies against SARS-CoV-2 in a cell-free engineering platform

In a groundbreaking bioRxiv paper, a research group from the Massachusetts Institute of Technology (MIT), Harvard University and Howard Hughes Medical Institute in the US engineered antibodies against the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein by using a novel approach. In doing so, they also identified more than 800 predicted binder families.

3 Nov 2020

Primary care for acute health conditions declined dramatically since UK lockdown

Researchers have conducted a study showing substantial reductions in the number of people attending primary care services for key physical and mental health conditions in the UK since lockdown was introduced on March 23rd this year.

3 Nov 2020

Earwax sampling could be a cheap, effective way to measure stress hormone

A novel method to sample earwax could be a cheap and effective way to measure the hormone cortisol, according to a study led by researchers at UCL and King's College London.

3 Nov 2020

Medical Research News

Study sheds light on possible lung damage caused by COVID-19 virus

Discoverey of four SARS-CoV-2 Mpro inhibitors, boceprevir, calpain inhibitors II and XII and GC-376

Most SARS-CoV-2-infected individuals develop durable B cell-mediated immunity

Evidence of robust and persistent antibodies against SARS-CoV-2

SARS-CoV-2 mutations becoming more contagious

SARS-CoV-2 T-cell immunity is retained for at least six months

United States is falling behind in the health care of older population, study shows

SARS-CoV-2 attack rates among household contacts higher than among non-household contacts

Study finds a subset of quick COVID-19 healers and antibody 'sustainers'

AI speech processing framework detects inaudible COVID-19 cough

Researchers track the flight trajectory of airborne cough droplets

Study shows active surveillance to be safe for African American men with low-risk prostate cancer

16 new lineages of SARS-CoV-2 emerge in South Africa despite lockdown

Researchers to explore the role of gut microbes in childhood celiac disease

Adaptive evolution of human coronaviruses may necessitate frequent reformulation of vaccines

Some of the main osteoporosis treatments could have a protective effect against COVID-19

Study identifies structural, functional brain differences in people with occupational blast exposure

Rapid generation of divergent synthetic antibodies against SARS-CoV-2 in a cell-free engineering platform

Primary care for acute health conditions declined dramatically since UK lockdown

Earwax sampling could be a cheap, effective way to measure stress hormone

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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