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Benefits of PSA screening for prostate cancer may outweigh potential harms

The benefits of the prostate-specific antigen (PSA) test to screen men for prostate cancer may be greater than the harm, according to a study published today in the New England Journal of Medicine.

22 Jun 2020

Researchers explore notions of animality, illness and humanity

When it became apparent in early 2020 just how serious the COVID-19-pandemic was, prioritization among corona patients became an acute issue.

22 Jun 2020

Simulation model reveals how sugary drink tax designs could impact health gains, costs

A simulation model of different designs of taxes on sugary drinks, which are linked to obesity, cardiovascular disease, and diabetes, suggests that all tax designs would generate substantial health gains as well as lower health costs in the U.S., according to new research published today in the American Heart Association's flagship journal Circulation.

22 Jun 2020

World-leading study aims to safeguard the health of refugee camp occupants

The Healthy Housing for the Displaced Project is a world-leading study into how to improve shelter design to help the physical, mental and social health for occupants of refugee camps

22 Jun 2020

GlobalData: Further research into MIS-C could reveal how COVID-19 affects the immune system

Some children have developed a severe inflammatory response due to COVID-19 infection that appears similar to Kawasaki disease.

22 Jun 2020

Pluripotent cells grown from osteoarthritic knee joint of elderly people

A break through feat of growing pluripotency expressing cells from osteoarthritis affected cartilage tissue of knee joints of elderly has been reported by orthopedicians and cell culture experts led by Dr Shojiro Katoh, President, Edogawa Hospital.

22 Jun 2020

How weather affects COVID-19 in India

With India now having endured six months of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, there are now over 410,000 official cases in and more than 13,000 deaths recorded. Almost all these deaths have occurred in the last three months, April to June, with 100 deaths on April 4, 2020, increasing almost 16-fold by May 4, and 63-fold by June 4, 2020.

21 Jun 2020

SARS-CoV-2 saliva testing that omits the RNA extraction step

Even as the COVID-19 pandemic progresses throughout the world, the lack of consistent diagnostic testing has been a bugbear, preventing public health control of the spread of infection. A new study by researchers at the University of Illinois Urbana-Champaign and published on the preprint server bioRxiv in June 2020 reports a new testing method that uses saliva, does not require RNA extraction, and can be scaled up quickly and inexpensively.

21 Jun 2020

Massive proteomics investigation of COVID-19 infection

Researchers from Germany and Switzerland revealed functional effects of individual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins on cellular level after infection. They placed the findings into the context of host signaling pathways in order to identify vulnerable parts of the virus amenable to treatment. The study is currently available on the bioRxiv preprint server.

21 Jun 2020

A highly sensitive and specific antibody test for COVID-19

A new proof-of-concept study by UK researchers, currently available on the medRxiv* preprint server, describes the development of an enzyme-linked immunosorbent assay that can be used when lower levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) specific-antibodies are present in serum and saliva samples.

21 Jun 2020

Research explores the biophysical behavior of SARS-CoV-2 nucleocapsid protein

In a groundbreaking paper currently available on the bioRxiv* preprint server, the researchers from the Washington University School of Medicine and Stony Brook University showed how nucleocapsid protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is dynamic, disordered and phase separates with RNA – informing, in turn, the discovery of drugs that disrupt viral packaging.

21 Jun 2020

Interesting study on which species may be infected by SARS-CoV-2

The team from the University of Cambridge and the Pirbright Institute found that the Spike protein on SARS-CoV-2 engages with the host cell receptor angiotensin-converting enzyme 2 (ACE2) across a wide range of animals, even though the Spike binding site shows a between-species variation in its amino acid composition.

21 Jun 2020

Promising candidate monoclonal antibodies show "exquisite potency" against SAR-CoV-2

Researchers at Columbia University, Dana-Farber Cancer Institute, and the National Institutes of Health have identified and characterized a range of monoclonal antibodies that potently neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

21 Jun 2020

Environmental conditions affect the stability of SARS-CoV-2, study finds

A new study led by Marshall University researcher M. Jeremiah Matson found that environmental conditions affect the stability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human nasal mucus and sputum.

21 Jun 2020

Infants tested positive for COVID-19 mostly have mild illness with fever

A report from Ann & Robert H. Lurie Children's Hospital of Chicago shows that infants under 90 days of age who tested positive for COVID-19 tend to be well, with little or no respiratory involvement. Fever was often found to be the primary or only symptom.

21 Jun 2020

Study finds widespread support for public health measures to limit spread of COVID-19

No mass gatherings. Stay-at-home orders. Nonessential business closures. Use of cloth face coverings. In April, these and other measures were adopted by states to try to mitigate the spread of COVID-19 in the U.S. and across the globe.

21 Jun 2020

Young adults from disadvantaged neighborhoods show differences in the epigenome

The neighborhood a child grows up in may influence their health for years to come in previously invisible ways.

21 Jun 2020

Study takes new treatment approach for blood cancer

In an effort to improve the survival of patients with myeloproliferative neoplasms, a type of leukemia, researchers inhibited a specific protein (alpha5beta1 integrin) to decrease the number of large bone marrow cells (megakaryocytes) in an experimental model.

21 Jun 2020

Study shows changes in brain dynamics at rest following a relationship breakup

During a person's life, the experience of a stressful life event can lead to the development of depressive symptoms, even in a non-clinical population.

21 Jun 2020

Researchers discover new and improved way to treat poor-prognosis blood cancer

Researchers at Children's Cancer Institute have discovered what could prove a new and improved way to treat the poor-prognosis blood cancer, acute myeloid leukemia or AML.

21 Jun 2020