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Oxford University and AstraZeneca resume COVID-19 vaccine trial

More than a hundred candidate vaccine trials against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), are underway. About 35 are now undergoing clinical evaluation, and of these, nine are in the final phase of human trials, including the vaccine developed by Oxford University and the biopharmaceutical firm, AstraZeneca.

14 Sep 2020

Researchers find coping techniques linked with positive mental health during COVID-19

The early days of the COVID-19 pandemic contributed to negative mental health effects for many in the U.S., according to new Penn State research. But the researchers also found that some coping techniques -- like wearing masks and focusing on self-care -- were linked with positive mental health.

14 Sep 2020

IU School of Medicine and partners receive funding to deploy collaborative dementia care model

Supported by a $1.3 million grant from the U.S. Administration for Community Living, Department of Health and Human Services, Indiana University School of Medicine and its partners have launched a 36-month venture to enhance, strengthen and expand supports for people with Alzheimer's Disease and Related Dementias (ADRD) and their caregivers in 34 Indiana counties.

14 Sep 2020

Circadian rhythm affects SARS-CoV-2 infection and host immune response

In an interesting bioRxiv preprint paper, French researchers show that the time day can affect infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as guide subsequent host immune response – implying that circadian rhythm may well be a novel target for managing viral progression.

14 Sep 2020

Drug for liver cirrhosis shows potential to treat dementia and motor neuron disease

A drug used to treat cirrhosis of the liver may be an effective treatment for a form of Dementia and motorneuron disease, scientists have discovered.

14 Sep 2020

Research finds genetic factors that protect from chronification of migraines

According to existing estimates, migraine is a highly prevalent ailment, with about 15 percent of global population suffering from it at one time or another.

14 Sep 2020

Earlier treatment with steroids reduces adverse outcomes in patients with septic shock

Some critically ill patients with septic shock need medications called vasopressors to correct dangerously low blood pressure.

14 Sep 2020

Keto diet could be beneficial for elderly COVID-19 patients

A recent study by researchers at Yale School of Medicine, New York University Langone Health and Washington University School of Medicine, claims that the ketogenic diet (high fat, low carbohydrate diet) is capable of mitigating clinical outcomes of coronavirus disease 2019 (COVID-19) in elderly people by improving immune-metabolic functions and reducing inflammation. The study is currently available on the bioRxiv* preprint server.

14 Sep 2020

Children's Hospital Los Angeles is U.S. site for new study of SARS-CoV-2 spread within households

One of the mysteries about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, is how it is spread within households, including why some family members develop the viral infection and others do not.

14 Sep 2020

UofL receives $11.5 million to accelerate the development of new immunotherapies

Cancer remains one of the most difficult and deadly challenges in human health, affecting Kentuckians at a higher rate than residents of any other state and killing more than 600,000 people each year in the U.S. alone.

14 Sep 2020

Computational models screen for coronaviruses likely to infect humans

The researchers from Rochester Institute of Technology and the Hauptmann-Woodward Medical Research Institute produced models of the receptor-binding domain (RBD) found on outbreak strains of betacoronaviruses and its interaction with the host cell receptor angiotensin-converting enzyme 2 (ACE2).

14 Sep 2020

Toyonaka Municipal Hospital reports successful control of COVID-19

Researchers at Toyonaka Municipal Hospital in Japan have shown that the rate of subclinical infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among staff at the hospital is no higher than among the general population in the same area.

14 Sep 2020

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine.

14 Sep 2020

Researchers develop new PET imaging agent that spotlights inflammation

Many of the most common diseases -- cancer, diabetes, cardiovascular and lung disease, and even COVID-19 -- have been linked to chronic or excessive inflammation.

14 Sep 2020

Are children more likely to be SARS-CoV-2 asymptomatic than adults?

he frequency of children carrying asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been suggested to be higher than among adults. It is also suggested that asymptomatic children enhance viral spread. A new study published in the journal JAMA Pediatrics in September 2020 explores the truth of this common belief.

14 Sep 2020

Should a COVID-19 vaccine be mandatory for children?

As the search for a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine continues, with some candidate vaccines nearing the completion Phase III clinical trials, a trio of experts weighs in with some sound reasoning as to whether any future vaccine should be considered mandatory for children. The viewpoint article is published in the journal JAMA Pediatrics in September 2020.

14 Sep 2020

COVID-19 pandemic affects delivery of cancer care and oncologists' wellbeing

Delays and cancellation of cancer treatments and other safety measures undertaken to minimise the risk of exposure to the coronavirus (COVID-19) have generated a huge backlog in oncology care and research.

14 Sep 2020

Researchers identify microRNA molecules that could repress the replication of human coronaviruses

HSE University researchers have found microRNA molecules that are potentially capable of repressing the replication of human coronaviruses, including SARS-CoV-2.

14 Sep 2020

Study: Cigarette smoking is linked to worse outcomes in patients treated for bladder cancer

Patients treated for bladder cancer with a surgery known as radical cystectomy have worse outcomes if they are smokers, according to a systematic review and meta-analysis by Keck Medicine of USC. The study appeared in The Journal of Urology.

14 Sep 2020

NIH provides additional support for large scale study of Alzheimer's disease biomarkers

To meet the pressing need to better understand the prevalence, progression, and clinical impact of Alzheimer's disease among Mexican Americans, the National Institutes of Health has added funding for more biomarker measures, including positron emission tomography imaging, to the ongoing Health and Aging Brain Among Latino Elders Study.

14 Sep 2020

Medical Research News

Oxford University and AstraZeneca resume COVID-19 vaccine trial

Researchers find coping techniques linked with positive mental health during COVID-19

IU School of Medicine and partners receive funding to deploy collaborative dementia care model

Circadian rhythm affects SARS-CoV-2 infection and host immune response

Drug for liver cirrhosis shows potential to treat dementia and motor neuron disease

Research finds genetic factors that protect from chronification of migraines

Earlier treatment with steroids reduces adverse outcomes in patients with septic shock

Keto diet could be beneficial for elderly COVID-19 patients

Children's Hospital Los Angeles is U.S. site for new study of SARS-CoV-2 spread within households

UofL receives $11.5 million to accelerate the development of new immunotherapies

Computational models screen for coronaviruses likely to infect humans

Toyonaka Municipal Hospital reports successful control of COVID-19

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Researchers develop new PET imaging agent that spotlights inflammation

Are children more likely to be SARS-CoV-2 asymptomatic than adults?

Should a COVID-19 vaccine be mandatory for children?

COVID-19 pandemic affects delivery of cancer care and oncologists' wellbeing

Researchers identify microRNA molecules that could repress the replication of human coronaviruses

Study: Cigarette smoking is linked to worse outcomes in patients treated for bladder cancer

NIH provides additional support for large scale study of Alzheimer's disease biomarkers

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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