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Health risks associated with NSAIDs as a factor for increased opioid prescribing

Patients with chronic pain caught between cardiovascular concerns about non-opioid analgesics and addiction risks of opioids, likely causing significant unmet need for pain relief.

11 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Skipping one night of sleep may exacerbate performance impairment in insomniacs

A new study conducted by researchers at Washington State University shows that individuals with chronic sleep-onset insomnia who pulled an all-nighter performed up to twice as bad on a reaction time task as healthy normal sleepers.

11 Dec 2019

Help for teenagers who want to quit smoking

A new study published in the journal JAMA Pediatricsreports on the use of varenicline, a drug that helps smokers quit. The study is unique in that it targeted teenagers who wanted to quit. While confirming the low overall efficacy of the drug, it shows that it may perhaps help teenage smokers to quit faster and to stay smoke-free longer.

11 Dec 2019

Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019

Study shows benefits of video discharge instructions for acute otitis media in children

Video discharge instructions in the emergency department are associated with less perceived acute otitis media symptomatology compared to a paper handout.

11 Dec 2019

Addictions and drug interactions common among patients not disclosing their medication history

Some patients skip telling their doctors about the drugs and medications they are consuming. A new study shows that these patients are at a greater risk of unpleasant and sometimes dangerous drug-drug interactions as well as addictions. The study was published in the latest issue of The Journal of the American Osteopathic Association. The study is titled, “Role of opioid-involved drug interactions in chronic pain management”.

11 Dec 2019

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings.

11 Dec 2019

Light to moderate lifetime alcohol use raises cancer risk

There have been conflicting reports on health benefits and harm caused by drinking alcohol. A new study from Japanese researchers has proven that taking one drink a day for a decade or two drinks for five years can raise the risk of getting cancers by 5 percent. The study titled “Light to moderate amount of lifetime alcohol consumption and risk of cancer in Japan,” was published in the latest issue of the journal Cancer.

11 Dec 2019

Non-drug therapies may reduce adverse outcomes in service members with chronic pain

A new study based on Veterans Affairs health records finds that non-drug therapies given to military service members with chronic pain may reduce the risk of long-term adverse outcomes, such as alcohol and drug disorder and self-induced injuries, including suicide attempts.

11 Dec 2019

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

Efforts to prevent new HIV transmissions in the United States must be accompanied by advances in addressing HIV-associated comorbidities to improve the health of people already living with HIV, National Institutes of Health experts assert in the third of a series of JAMA commentaries.

11 Dec 2019

Loneliness epidemic in the US tied to increasing ageing population

In contrast to previous reports that the U.S. population has increasing rates of loneliness and isolation, a new report shows that it’s not entirely true, at least for baby boomers. Older people may not be any lonelier than their counterparts from previous generations, there are just more of them.

11 Dec 2019

Children of all age groups around the world at risk from decline in physical activity

Emphasis on particular groups hinders efforts to address the problem of declining physical activity in children, according to a study led at the University of Strathclyde.

11 Dec 2019

Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's

The colour of our eyes or the straightness of our hair is linked to our DNA, but the development of Alzheimer's disease isn't exclusively linked to genetics, suggest recently published findings.

11 Dec 2019

Chemical found in tropical flower could help to treat deadly pancreatic cancer

An international team of scientists led by the University of Bath have made drug-like molecules inspired by a chemical found in a tropical flower, that they hope could in the future help to treat deadly pancreatic cancer.

11 Dec 2019

Researchers test vaccine strategy for chronic inflammatory diseases

Chronic inflammatory bowel diseases, such as Crohn's Disease and ulcerative colitis, are linked to abnormalities of the gut microbiota in humans and in animals. Patients generally present reduced bacterial diversity in their intestinal flora along with excessive levels of bacteria that express a protein called flagellin, which favors their mobility.

11 Dec 2019

Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high blood sugar levels, poorly controlled Type 2 diabetes has a host of well-recognized complications: compared with the general population, a greatly increased risk of kidney disease, vision loss, heart attacks and strokes, and lower limb amputations.

11 Dec 2019

Cannabis use in the U.S. increases rapidly among persons with depression

Results of a new study suggest that over the past decade (2005-2017), the prevalence of cannabis use in the United States has increased among persons with and without depression, though the increase is significantly more rapid among those with depression.

11 Dec 2019

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies.

11 Dec 2019

Study shows how diet plays a role in age-related macular degeneration

Participants who ate a diet high in red and processed meat, fried food, refined grains and high-fat dairy were three times more likely to develop an eye condition that damages the retina and affects a person's central vision, according to the results of a study from the University at Buffalo.

11 Dec 2019

Medical Research News

Health risks associated with NSAIDs as a factor for increased opioid prescribing

New drug combo promises help for triple negative breast cancer patients

Skipping one night of sleep may exacerbate performance impairment in insomniacs

Help for teenagers who want to quit smoking

Experimental Alzheimer’s drugs show promise

Study shows benefits of video discharge instructions for acute otitis media in children

Addictions and drug interactions common among patients not disclosing their medication history

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

Light to moderate lifetime alcohol use raises cancer risk

Non-drug therapies may reduce adverse outcomes in service members with chronic pain

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

Loneliness epidemic in the US tied to increasing ageing population

Children of all age groups around the world at risk from decline in physical activity

Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's

Chemical found in tropical flower could help to treat deadly pancreatic cancer

Researchers test vaccine strategy for chronic inflammatory diseases

Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

Cannabis use in the U.S. increases rapidly among persons with depression

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Study shows how diet plays a role in age-related macular degeneration

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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