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University Of Iowa wins $18 million grant to continue study on Huntington's disease

Peg Nopoulos, MD, chair of psychiatry and professor of psychiatry, neurology, and pediatrics in the University of Iowa Carver College of Medicine, has received a five-year, $18 million grant from the National Institute of Neurological Disorders and Stroke to continue and expand a decade-long study on brain development in children at risk for developing Huntington's Disease.

11 Dec 2019

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body's natural defenses against several forms of cancer, opening up a new era of cancer immunotherapy.

11 Dec 2019

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

UCLA scientists have discovered one reason why autoimmune diseases are more prevalent in women than in men.

11 Dec 2019

Immune cells repair damaged gut in children with IBD

According to a new study published in the journal Gastroenterology, immune cells of a certain kind which regulate inflammatory processes and even help restore normal gut function after inflammation could be of great use to treat children with inflammatory bowel disease (IBD).

11 Dec 2019

Gut disease and gene analysis networks

Gut diseases are difficult to diagnose in many cases, and their underlying dysfunction is hard to understand in many cases. Now, a new study published in the journal Molecular Omics promises to uncover a better insight into how these conditions occur and their mechanisms, by providing a deeper look at how genes interact in complex ways in health and fail to do so in disease.

11 Dec 2019

Specific brain circuit linked to food impulsivity discovered

You're on a diet, but the aroma of popcorn in the movie theater lobby triggers a seemingly irresistible craving.

11 Dec 2019

Epigenome editing could repair genetic brain disorder

A new study published in the journal Nature Communications shows that it may be possible to reverse gene mutations that cause brain disorders, using a very precisely targeted epigenome editing technique. This type of gene editing does not change the gene’s DNA sequence itself but is focused on correcting epigenome changes only. The condition that was corrected in the study is called the WAGR syndrome and is associated with obesity and intellectual disability in people.

11 Dec 2019

Health risks associated with NSAIDs as a factor for increased opioid prescribing

Patients with chronic pain caught between cardiovascular concerns about non-opioid analgesics and addiction risks of opioids, likely causing significant unmet need for pain relief.

11 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Skipping one night of sleep may exacerbate performance impairment in insomniacs

A new study conducted by researchers at Washington State University shows that individuals with chronic sleep-onset insomnia who pulled an all-nighter performed up to twice as bad on a reaction time task as healthy normal sleepers.

11 Dec 2019

Help for teenagers who want to quit smoking

A new study published in the journal JAMA Pediatricsreports on the use of varenicline, a drug that helps smokers quit. The study is unique in that it targeted teenagers who wanted to quit. While confirming the low overall efficacy of the drug, it shows that it may perhaps help teenage smokers to quit faster and to stay smoke-free longer.

11 Dec 2019

Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019

Study shows benefits of video discharge instructions for acute otitis media in children

Video discharge instructions in the emergency department are associated with less perceived acute otitis media symptomatology compared to a paper handout.

11 Dec 2019

Addictions and drug interactions common among patients not disclosing their medication history

Some patients skip telling their doctors about the drugs and medications they are consuming. A new study shows that these patients are at a greater risk of unpleasant and sometimes dangerous drug-drug interactions as well as addictions. The study was published in the latest issue of The Journal of the American Osteopathic Association. The study is titled, “Role of opioid-involved drug interactions in chronic pain management”.

11 Dec 2019

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings.

11 Dec 2019

Light to moderate lifetime alcohol use raises cancer risk

There have been conflicting reports on health benefits and harm caused by drinking alcohol. A new study from Japanese researchers has proven that taking one drink a day for a decade or two drinks for five years can raise the risk of getting cancers by 5 percent. The study titled “Light to moderate amount of lifetime alcohol consumption and risk of cancer in Japan,” was published in the latest issue of the journal Cancer.

11 Dec 2019

Non-drug therapies may reduce adverse outcomes in service members with chronic pain

A new study based on Veterans Affairs health records finds that non-drug therapies given to military service members with chronic pain may reduce the risk of long-term adverse outcomes, such as alcohol and drug disorder and self-induced injuries, including suicide attempts.

11 Dec 2019

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

Efforts to prevent new HIV transmissions in the United States must be accompanied by advances in addressing HIV-associated comorbidities to improve the health of people already living with HIV, National Institutes of Health experts assert in the third of a series of JAMA commentaries.

11 Dec 2019

Loneliness epidemic in the US tied to increasing ageing population

In contrast to previous reports that the U.S. population has increasing rates of loneliness and isolation, a new report shows that it’s not entirely true, at least for baby boomers. Older people may not be any lonelier than their counterparts from previous generations, there are just more of them.

11 Dec 2019

Children of all age groups around the world at risk from decline in physical activity

Emphasis on particular groups hinders efforts to address the problem of declining physical activity in children, according to a study led at the University of Strathclyde.

11 Dec 2019

Medical Research News

University Of Iowa wins $18 million grant to continue study on Huntington's disease

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

Immune cells repair damaged gut in children with IBD

Gut disease and gene analysis networks

Specific brain circuit linked to food impulsivity discovered

Epigenome editing could repair genetic brain disorder

Health risks associated with NSAIDs as a factor for increased opioid prescribing

New drug combo promises help for triple negative breast cancer patients

Skipping one night of sleep may exacerbate performance impairment in insomniacs

Help for teenagers who want to quit smoking

Experimental Alzheimer’s drugs show promise

Study shows benefits of video discharge instructions for acute otitis media in children

Addictions and drug interactions common among patients not disclosing their medication history

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

Light to moderate lifetime alcohol use raises cancer risk

Non-drug therapies may reduce adverse outcomes in service members with chronic pain

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

Loneliness epidemic in the US tied to increasing ageing population

Children of all age groups around the world at risk from decline in physical activity

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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