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Dual action of genes and RNA influences aggressive triple-negative breast cancer

Women with an aggressive, less-common type of breast cancer, known as triple-negative, versus a more common form of the disease, could be differentiated from each other by a panel of 17 small RNA molecules that are directly influenced by genetic alterations typically found in cancer cells.

22 Oct 2019

High glucose impairs circadian clock function, may increase cardiovascular risk

High glucose in obesity appears to gum up the works of the circadian clocks inside our cells that help regulate the timing of many body functions across the 24-hour day and drive the risk of cardiovascular disease, scientists say.

22 Oct 2019

Researchers develop simple, low-cost way to predict preeclampsia

Australian researchers have developed a way to predict the onset of a deadly pregnancy condition that kills 76,000 women and half a million babies each year, mostly in developing countries.

22 Oct 2019

New treatment shows promise to reverse celiac disease

Results of a new phase 2 clinical trial using technology developed at Northwestern Medicine show it is possible to induce immune tolerance to gluten in individuals with celiac disease. The findings may pave the way for treated celiac patients to eventually tolerate gluten in their diet.

22 Oct 2019

Local researchers often lost in the shadows in international projects

A new Harvard Medical School analysis shows that papers that present research on health conditions within sub-Saharan African countries in collaboration with wealthy or prestigious institutions or countries often fail to mention local researchers working on the same project, especially in prime positions such as first or senior author. The paper was published on October 18, 2019, in the journal BMJ Global Health.

22 Oct 2019

One in three patients may experience side effects from ketamine infusions for pain management

As the opioid epidemic continues to devastate the United States, ketamine use has grown as a pain management alternative, yet more than one in three patients may experience side effects such as hallucinations and visual disturbances, suggests new research presented at the ANESTHESIOLOGY 2019 annual meeting.

21 Oct 2019

Study to examine whether cancer and co-occurring Alzheimer's alter pain perception

A new multisite study funded by the National Institute on Aging will examine whether co-occurring Alzheimer's disease and stage 4 breast or prostate cancer alters pain perception, potentially leading to undertreated cancer pain.

21 Oct 2019

CHOP offers help and cure for children with overly picky eating habits

Families dealing with the stress and frustration of their child's overly picky eating habits may have a new addition to their parental toolbox.

21 Oct 2019

Performance-enhancing with ... potatoes!

Athletes who are training need to go through grueling endurance tests. One proven strategy to boost their performance during such tests is to eat carbohydrates as race fuels. Now, an interesting study published on October 20, 2019, in the Journal of Applied Physiology reports that athletes in training could get their energy just as well from a mound of pureed potato, rather than spending money on commercial carbohydrate pastes that don’t do the job any better.

21 Oct 2019

IBD far more common than expected, and will only increase in future

There are three times as many people with the chronic and debilitating bowel disorder called inflammatory bowel disease (IBD) as ever thought before, according to a new study presented today at UEG Week 2019, at Barcelona. Not only is the condition a distressing one in itself, but patients with IBD have a higher risk of colorectal cancer as well.

21 Oct 2019

Autism spectrum disorder could be triggered by low placental steroid levels

A recent experimental study has shown that one reason for the occurrence of autism spectrum disorder (ASD) could be the deficit of a placental steroid hormone called allopregnanolone. The reason is that this hormone plays a critical role in the normal development of the brain in fetal life.

21 Oct 2019

Antibiotic resistance doubles in just two decades

Antibiotic resistance poses a grave challenge to many previously curable infectious diseases. At present, antibiotic resistance is proving to increase at a much faster rate compared to the development of new therapies.

21 Oct 2019

Family members can help reduce the incidence of post-operative delirium by up to 16.8%

In a study published today in JAMA Internal Medicine, researchers reported that training family members in delirium prevention approaches can significantly reduce the incidence of post-operative delirium by up to 16.8 percent within seven days after surgery.

21 Oct 2019

Researchers analyze trends in episiotomy use among vaginal deliveries

In Canada, the rate of episiotomy during childbirth has declined in recent years, but when it comes to births assisted by forceps or vacuum, this downward trend warrants a closer look, suggests new UBC research.

21 Oct 2019

Healthiest gut bacteria with plant-based or Mediterranean diet

A new study shows that specific foods that are supplied by either a plant-based or a Mediterranean-type diet can protect the gut against inflammatory disorders, by selectively promoting the growth of anti-inflammatory bacteria.

21 Oct 2019

Creatine powers fight against cancer, improves efficacy of immunotherapies

The immune system functions as the body’s defense against pathogens and harmful substances, including cancer cells. They protect the body against potential harm. In cases of cancer, though the body tries to fight the tumor cells, they may become too aggressive for the immune system to eradicate.

21 Oct 2019

New findings demonstrate how subtle social interactions can impact clinical outcomes

If a doctor expects a treatment to be successful, a patient may experience less pain and have better outcomes, according to a new Dartmouth study published in Nature Human Behaviour.

21 Oct 2019

Cantabio, LIH jointly investigate DJ-1 targeting compounds in immune associated diseases

DJ-1 is well known as an important target for the treatment of a number of diseases such as Parkinson's disease. Cantabio has been developing novel small molecule therapeutic program targeting the DJ-1 protein with a focus on Parkinson's and also exploring a number of other disease areas.

21 Oct 2019

Salk Institute scientists receive NIH grant to better understand the brain

Salk Institute scientists Nicola Allen, Eiman Azim, Margarita Behrens, and Joseph Ecker have been named recipients in the 2019 round of grants from the National Institutes of Health (NIH) to better understand the brain.

21 Oct 2019

Researchers use mouse model to better understand mechanism involved in atrial fibrillation

Atrial fibrillation is the most common heart arrhythmia in humans. This condition increases the risk of heart failure, stroke, dementia and death, and current treatments have suboptimal efficacy and carry side effects.

21 Oct 2019