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Biodegradable bridge for nerve injuries

Researchers have successfully tried a biodegradable bridge like device (biodegradable polycaprolactone PCL conduit) in vivo for management of nerve injuries. The team published their findings in a paper titled, “Long-gap peripheral nerve repair through sustained release of a neurotrophic factor in nonhuman primates,” in the latest issue of the journal Science Translational Medicine.

26 Jan 2020

Snake stem cells create real venom to use as medicine

Poisonous snakes kill more than 90,000 people each year across the globe, with about 1.2 million to 5.5 million snake bites occur annually. Despite the venomous bite, scientists have limited knowledge of the snake’s venom, complicating efforts to develop treatments. A new study has found that snake venom gland cells can be cultured in the lab as adult-stem-cell-based organoids, producing real venom, which can be used to develop treatments.

26 Jan 2020

Puberty blockers reduce suicidal ideations among transgender teens

Transgender teens have a higher risk of having suicidal ideations, reports the U.S. Centers for Disease Control and Prevention (CDC). A new study suggests that having access to puberty blockers can significantly reduce the risk of suicide and other mental health issues.

26 Jan 2020

A microdose lithium formulation could halt signs of Alzheimer's pathology

There remains a controversy in scientific circles today regarding the value of lithium therapy in treating Alzheimer's disease.

24 Jan 2020

Early life exposure to traffic-related air pollution may cause structural brain changes at age 12

A new study suggests that significant early childhood exposure to traffic-related air pollution (TRAP) is associated with structural changes in the brain at the age of 12.

24 Jan 2020

UMD entomologists recognized by AAAS with 2019 Newcomb Cleveland Prize

The American Association for the Advancement of Science awarded its 2019 Newcomb Cleveland Prize to University of Maryland entomologists Raymond St. Leger, Brian Lovett and their seven West African collaborators.

24 Jan 2020

UCI-led study reveals link between early life adversity and opioid addiction

Individuals with a history of early life adversity are disproportionately prone to opioid addiction. A new UCI-led study reveals why.

24 Jan 2020

Taming pathogens with mucus and phages

Millions of people are treated with antibiotics each year for infections or as a preventative measure. The Centers for Disease Control and Prevention reports that at least 2.8 million people are infected with antibiotic-resistant bacteria each year, meaning the germs have found ways to overpower antibiotics and continue to grow.

24 Jan 2020

The influence of neuroanatomy on treatment response of patients with trigeminal neuralgia

A new study published in the journal Cephalalgia, the official journal of the International Headache Society, shows unprecedented data regarding the neuroanatomical influence on the treatment response of patients with trigeminal neuralgia.

24 Jan 2020

Non-hormonal options are effective in treating menopause symptoms

The classic symptoms of menopause – hot flashes, sleeplessness, and vaginal dryness – have typically been treated with estrogen therapy. Studies published today report that non-hormonal options are effective, too.

24 Jan 2020

Opioid dependence produces permanent changes in the brains of rats

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction.

24 Jan 2020

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders.

24 Jan 2020

Majority of people knowingly use fentanyl, UBC research shows

Fentanyl use by people who use drugs has doubled since 2015, and two-thirds of people are aware they've taken it, finds new research out of British Columbia, the Canadian province that has experienced the highest number of illicit drug toxicity deaths as a result of the opioid crisis.

24 Jan 2020