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Loss of stress hormone is a hallmark of pancreatitis, shows study

In work that could have clinical implications, UT Southwestern researchers find that humans and mice with pancreatitis are deficient in a stress hormone called FGF21.

9 Jan 2020

SVC112 molecule acts specifically against head and neck cancer stem cells

The red, tube-shaped flowers of the firecracker bush (Bouvardia ternifolia), native to Mexico and the American Southwest, attract hummingbirds.

8 Jan 2020

Researchers develop a simple approach to accurately predict disease outbreaks

Infectious diseases have a substantially growing impact on the health of communities around the world and pressure to both predict and prevent such diseases is ever-growing.

8 Jan 2020

Insilico and Beiersdorf use next-generation AI technology in skin research

Beiersdorf and Insilico Medicine, an artificial intelligence company developing end to end drug discovery pipelines, announced today that they are entering a collaboration to jointly discover novel, safe bioactive ingredients for a specific skin indication at an unparalleled pace, that will serve as the basis for developing appropriate skincare products.

8 Jan 2020

Single-particle method helps determine isoelectric point of viruses

Viruses are not easy to characterize. But we need to because being able to quickly predict the surface charge of viruses opens up new possibilities for vaccine purification and making gene therapy treatments for eye diseases and muscular dystrophy.

8 Jan 2020

Study: Less than 2% of people at risk for opioid overdose are prescribed life-saving drug

Only a tiny minority of people at risk for an opioid overdose actually are prescribed a drug that could save their lives, a new study suggests. And the odds of having a dose of the rescue drug were very low among some of the most at-risk groups, including those who had already survived a previous opioid overdose.

8 Jan 2020

FSU discovery could open the door to new treatment options for HIV, hepatitis B

A discovery by Florida State University College of Medicine researchers is expected to open the door for new and more potent treatment options for many of the more than 36 million people worldwide infected with the HIV virus and for others chronically ill with hepatitis B.

8 Jan 2020

Changing the underlying structure and culture of a clinic to address opioid epidemic

For the 20 percent of Americans who suffer from chronic pain, prescription opioids may bring relief, but also risks. An estimated 21 to 29 percent of patients who receive chronic opioid treatment will misuse their medications, and 8 to 12 percent will develop an opioid use disorder.

8 Jan 2020

Study examines the time trends in alcohol and marijuana detected in homicide victims

Researchers at Columbia University Mailman School of Public Health assessed the time trends in alcohol and marijuana detected in homicide victims and found that the prevalence of marijuana almost doubled, increasing from 22 percent in 2004 to 42 percent in 2016.

8 Jan 2020

UC Riverside research team receives NIH grant to study breast cancer

A research team led by biochemists at the University of California, Riverside, has received a four-year grant from the National Institutes of Health, or NIH, to study breast cancer -- the most common cancer in women worldwide -- and the racial disparities in the treatment of the disease.

8 Jan 2020

Rapid correction of hyperkalemia reduces mortality by half

In a new study published in the American Journal of Emergency Medicine, Adam Singer, MD, et al reported that quickly correcting high potassium levels, a condition known as hyperkalemia, in emergency department patients cut mortality in that population by half.

8 Jan 2020

Missing one night of sleep may increase Alzheimer's biomarker, study finds

A preliminary study has found that when young, healthy men were deprived of just one night of sleep, they had higher levels of tau, a biomarker for Alzheimer's disease, in their blood than when they had a full, uninterrupted night of rest.

8 Jan 2020

Post-mortem genetic testing used to find underlying cause of sudden deaths in Amish families

Researchers used post-mortem genetic testing to find the underlying cause of multiple sudden deaths in young people and sudden cardiac arrests in two large Amish families.

8 Jan 2020

Minimally invasive technique to directly measure cardiac output in newborns

The amount of blood that the heart pumps in one minute (cardiac output) can be directly measured safely in newborns by monitoring changes in blood velocity after injecting saline, indicates a paper published online Dec. 17, 2019 in the Journal of Pediatrics and Neonatal Medicine.

8 Jan 2020

Cystic fibrosis carriers have higher risk for all CF-related conditions

Conventional wisdom says that having just one mutated copy of the cystic fibrosis gene has no effects on a person's health--the disease occurs when both copies of the gene are mutated. But a new study from the University of Iowa suggests that may not be the case.

8 Jan 2020

New hydrogel prevents and treats infections in wounds

Researchers at Lund University in Sweden have developed a new hydrogel based on the body's natural peptide defense.

8 Jan 2020

Researchers study the effects of antidepressants to identify the least harmful drugs

About one in ten women in Québec will suffer from depression during pregnancy. Without treatment, the illness carries risks for both mother and child.

8 Jan 2020

Persistent physical activity from childhood to adulthood linked to higher fruit and vegetable consumption

A physically active lifestyle and a diet rich in vegetables and fruits have a central role in promoting health by preventing non-communicable diseases.

8 Jan 2020

Researchers discover hundreds of novel viruses in insects

New viruses which cause diseases often come from animals. Well-known examples of this are the Zika virus transmitted by mosquitoes, bird flu viruses, as well as the MERS virus which is associated with camels. In order to identify new viral diseases quickly and prevent possible epidemics, DZIF scientists at Charité - Universitätsmedizin Berlin are targeting their search at viruses in animals.

8 Jan 2020

Two-drug combination could be effective against malignant mesothelioma

Exposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggressive cancer that mostly affects the pleura - the tissue that lines the lungs - and the peritoneum - the tissue that lines the abdomen. This has been known for decades, yet the molecular characterisation of mesothelioma is barely known and treatment options are scarce.

8 Jan 2020