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Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often prescribed to lower cholesterol, block this metabolic pathway and cause the cancer cells to die, as scientists from the German Cancer Research Center have now discovered.

12 Dec 2019

Researchers aim to improve oral delivery of insulin for diabetes patients

Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin -- a hormone that regulates blood sugar-- or the body cannot effectively use the insulin it produces.

12 Dec 2019

Dendritic cells could lead to better treatments for persistent infections, cancer

Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose role is to fight against disease-causing pathogens, turning against itself.

12 Dec 2019

Using artificial intelligence to help mitigate suicide risk

According to the CDC, the suicide rate for individuals 10-24 years old has increased 56% between 2007 and 2017.

12 Dec 2019

New book provides extensive research into health effects of football

The new book "Football as Medicine - Prescribing Football for Global Health Promotion" collates 15 years of research when describing the effects of football training on cardiovascular, metabolic and musculoskeletal fitness, and providing up-to-date knowledge of the impact of recreational football for target populations like children, type 2 diabetes patients, cancer patients, people with mental health conditions, the socially deprived and older people.

12 Dec 2019

New research finds no evidence that front foot running reduces injury risk

New research from La Trobe University suggests there is no evidence that changing a runner's strike pattern will help prevent injuries or give them a speed boost.

12 Dec 2019

Clinical Research Pathways, WellStar Health System partner to increase diversity in oncology research

Clinical Research Pathways is partnering with WellStar Health System to increase diversity in oncology research to help ensure that new cancer medicines are effective for patients of all races and ethnicities.

12 Dec 2019

Researchers making major inroads into finding the cause of different diseases

Australian researchers are making major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected by oxidative stress in the human body.

12 Dec 2019

Could summer holidays have an adverse impact on kids’ health?

As thousands of Aussie kids start summer holidays this week, there's no doubt parents will see an increase in kids' screen time, snack time and general relaxation.

12 Dec 2019

New insights into the most perplexing medical mysteries associated with schizophrenia

Four unsolved mysteries around schizophrenia have long plagued the medical community, but a new hypothesis identifying a common link between them and an almost forgotten epidemic of a disease called pellagra could have profound implications for our understanding of psychosis in poorer nations.

12 Dec 2019

New antimicrobial polymer can kill bacteria resistant to common antibiotics

Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, and Nanyang Technological University have designed an antimicrobial polymer that can kill bacteria resistant to commonly used antibiotics, including the superbug Methicillin-resistant Staphylococcus aureus (MRSA).

12 Dec 2019

Study: 18% of outpatient antibiotic prescriptions written without a documented reason

A study of outpatient visits to health care providers in the United States during a one-year period suggests 18 percent of antibiotic prescriptions were written without a documented reason for doing so.

12 Dec 2019

Study looks at flu vaccine requirement for children, caregivers in U.S. child care centers

Influenza can be especially dangerous for children, who are at greater risk for serious complications from the illness, including hospitalization and even death.

12 Dec 2019

Depression and anxiety can have negative impact on outcomes following hip surgery

New research suggests that physicians evaluating young patients with hip pain should consider more than such patients' physical health. They also should consider screening those patients for clinical depression and anxiety -- impairments that researchers at Washington University School of Medicine in St. Louis have found can have a negative impact on outcomes following hip surgery, such as pain, slower recoveries and inadequate return to activity.

12 Dec 2019

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

Researchers have vaccinated mice against the Zika virus, whilst others have discovered a new platform for flavivirus vaccines.

12 Dec 2019

Sleep helps the brain consolidate information stored in long-term memory

A review of more than 130 studies explains how sleep helps people learn new information and plays an important role in storing learned content for future use. The review is published in the January 2020 issue of Physiology.

12 Dec 2019

Nurses' sleep duration before work may impact quality of care and patient safety

Nurses sleep nearly an hour and a half less before work days compared to days off, which hurts patient care and safety, finds a new study by researchers at NYU Rory Meyers College of Nursing. The findings are published in Sleep Health, the journal of the National Sleep Foundation.

12 Dec 2019

Medical Research News

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Researchers aim to improve oral delivery of insulin for diabetes patients

Dendritic cells could lead to better treatments for persistent infections, cancer

Using artificial intelligence to help mitigate suicide risk

New book provides extensive research into health effects of football

New research finds no evidence that front foot running reduces injury risk

Clinical Research Pathways, WellStar Health System partner to increase diversity in oncology research

Researchers making major inroads into finding the cause of different diseases

Could summer holidays have an adverse impact on kids’ health?

New insights into the most perplexing medical mysteries associated with schizophrenia

New antimicrobial polymer can kill bacteria resistant to common antibiotics

Study: 18% of outpatient antibiotic prescriptions written without a documented reason

Study looks at flu vaccine requirement for children, caregivers in U.S. child care centers

Depression and anxiety can have negative impact on outcomes following hip surgery

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

Sleep helps the brain consolidate information stored in long-term memory

Nurses' sleep duration before work may impact quality of care and patient safety

Study suggests antiarrhythmic drug as potential treatment for pulmonary arterial hypertension

Brain imaging of veterans reveals two subtypes of Gulf War illness

A recombinant platform for flavivirus vaccines and diagnostics using chimeras

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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