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Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial led by investigators at The University of Texas MD Anderson Cancer Center presented today at the American Society of Clinical Oncology Genitourinary Cancers Symposium in San Francisco.

15 Feb 2019

Immune checkpoint molecule protects against future development of cancer

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

15 Feb 2019

Index endoscopy results are crucial for assessment of Barrett's patients

A new study indicates that both high-grade abnormal cellular changes (dysplasia) and esophageal adenocarcinoma (a form of cancer) have increased in the last 25 years among people with a digestive condition known as Barrett's esophagus.

15 Feb 2019

New injury documentation tool may provide better evidence for elder abuse cases

An estimated 10 percent of older adults experience some form of abuse each year. However, the link between injuries and possible elder abuse may take months or years to establish and is often difficult to investigate due to poor documentation during prior medical visits.

15 Feb 2019

WVU gynecologic oncologist investigates novel treatment for cervical and vaginal cancers

Cervical cancer can be insidious. Changes to the cervix are often detected with a pap smear, but for those with limited access to health care, cervical and vaginal cancers can go unnoticed for years--silently growing, spreading and invading other organs--and by the time they're detected, they may be so advanced that the patient's prognosis is poor and her treatment options few.

15 Feb 2019

Newly developed stem cell technologies show promise for treating PD patients

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

15 Feb 2019

Sausage mislabeling in Canada is down, new study finds

Sausage mislabelling in Canada is down, according to a new University of Guelph DNA barcoding study.

15 Feb 2019

Large-scale clinical trial begins to study liver transplantation between people with HIV

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery.

15 Feb 2019

High-protein and low-calorie diet helps older adults lose weight safely, shows study

A high-protein, low-calorie diet helps older adults with obesity lose more weight, maintain more muscle mass, improve bone quality and lose "bad" fat, according to results from a new randomized controlled trial led by Wake Forest University researcher Kristen Beavers.

15 Feb 2019

Suspicious spots on the lungs of children with rhabdomyosarcoma do not behave like metastases

Rhabdomyosarcoma is a malignant soft tissue tumor in the muscle tissue of children and adolescents. About 20 children are diagnosed with rhabdomyosarcoma per year in the Netherlands. "Metastases in these children are often found in the lungs," says professor Hans Merks of the Princess Máxima Center for Pediatric Oncology, who led the study.

15 Feb 2019

Moffitt researchers shed light on how CAR T cells function mechanistically

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells.

15 Feb 2019

Decolonization protocol after hospital discharge can prevent dangerous infections

Hospital patients who have methicillin-resistant Staphylococcus aureus can prevent future MRSA infections by following a standard bathing protocol after discharge, according to research results published in the February 14 issue of the New England Journal of Medicine.

15 Feb 2019

Brain synchronization depends on the language of communication

Experts from the Basque research center BCBL have shown for the first time that the way in which the activity of two brains is connected depends on whether the dialogue takes place in the native language or in a foreign language.

15 Feb 2019

New therapeutic molecules show promise in reversing memory loss related to depression, aging

New therapeutic molecules developed at Toronto's Centre for Addiction and Mental Health show promise in reversing the memory loss linked to depression and aging.

15 Feb 2019

Blood-brain barrier disruption could lead to age-related cognitive decline

As our brains age, we become more forgetful, more tired and less able to do the cognitive gymnastics of our youth.

15 Feb 2019

Genetic variations in a fourth gene associated with higher ALL risk in Hispanic children

St. Jude Children's Research Hospital scientists have identified genetic variations in a fourth gene that are associated with an increased risk of acute lymphoblastic leukemia in Hispanic children. The research appears today in the journal Blood.

15 Feb 2019

Personal, social factors play role in enabling sustainable return to work after ill health

Support from managers and colleagues, as well as a positive attitude, are most likely to enable a more long-term return to work for employees after a sickness absence, according to a new review of research led by the University of East Anglia.

15 Feb 2019

Study: General anesthesia in early infancy unlikely to have lasting effects on developing brains

A single hour of general anesthesia in early infancy—longer than is necessary to perform the most common types of minor surgeries in childhood—does not result in measurable neurodevelopmental or behavioral problems up to the age of 5 years, according to the first randomized trial of its kind involving 722 infants in seven countries, published in The Lancet.

15 Feb 2019

Cell manipulation could soon halt or reverse aging

Researchers have shown that tweaking the tiny inner parts of a cell could prevent the damage caused due to aging.

15 Feb 2019

New study reveals high success rate for hip and knee replacements

After reviewing thousands of case studies going back 25 years across six countries, generalizable survival data is now available for the first time to estimate how long hip and knee replacements are likely to last.

14 Feb 2019

Medical Research News

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Immune checkpoint molecule protects against future development of cancer

Index endoscopy results are crucial for assessment of Barrett's patients

New injury documentation tool may provide better evidence for elder abuse cases

WVU gynecologic oncologist investigates novel treatment for cervical and vaginal cancers

Newly developed stem cell technologies show promise for treating PD patients

Sausage mislabeling in Canada is down, new study finds

Large-scale clinical trial begins to study liver transplantation between people with HIV

High-protein and low-calorie diet helps older adults lose weight safely, shows study

Suspicious spots on the lungs of children with rhabdomyosarcoma do not behave like metastases

Moffitt researchers shed light on how CAR T cells function mechanistically

Decolonization protocol after hospital discharge can prevent dangerous infections

Brain synchronization depends on the language of communication

New therapeutic molecules show promise in reversing memory loss related to depression, aging

Blood-brain barrier disruption could lead to age-related cognitive decline

Genetic variations in a fourth gene associated with higher ALL risk in Hispanic children

Personal, social factors play role in enabling sustainable return to work after ill health

Study: General anesthesia in early infancy unlikely to have lasting effects on developing brains

Cell manipulation could soon halt or reverse aging

New study reveals high success rate for hip and knee replacements

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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