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Antenatal renal pelvis dilatation increases risk of hospital admissions in early childhood

Babies who have persistent fluid-filled areas in their kidneys during gestation are likely to present with urinary tract problems and to be admitted to hospital in early childhood, according to new research published by Shantini Paranjothy and colleagues at Cardiff University, UK in the open access journal PLOS Medicine on July 30.

From PLOS ONE 31 Jul 2019

Brand–brand competition unlikely to lower list prices of brand-name drugs

Greater brand–brand competition alone will likely not lower list prices of brand-name drugs in the US, according to a study published July 30 in the open-access journal PLOS Medicine by Ameet Sarpatwari of Brigham and Women’s Hospital and Harvard Medical School, and colleagues.

From PLOS ONE 31 Jul 2019

Preventing parasites from adhering to mosquito guts could stop disease transmission

A group of microorganisms known as kinetoplastids includes the parasites that cause devastating diseases such as African sleeping sickness, Chagas disease, and leishmaniasis.

31 Jul 2019

International collaborative pinpoints key areas to catalyze nutrition-based cancer prevention

An international collaborative led by Ludwig Cancer Research and Cancer Research UK has identified key areas that are central to uncovering the complex relationship between nutrition and cancer.

31 Jul 2019

Genetic and environmental factors play major roles in the onset of vitiligo

A pair of new journal articles by researchers at the University of Colorado School of Medicine indicate that both genetic and environmental factors play significant roles in the onset of vitiligo, an autoimmune disease that results in the loss of color in blotches of skin.

31 Jul 2019

Autonomic nervous system of babies functions well regardless of mode of delivery, study finds

Late in pregnancy, the human body carefully prepares fetuses for the rigors of life outside the protection of the womb. Levels of cortisol, a stress hormone, ramp up and spike during labor.

31 Jul 2019

Johns Hopkins researchers use nanotechnology to repair faulty brain circuits

Working with mouse and human tissue, Johns Hopkins Medicine researchers report new evidence that a protein pumped out of some — but not all — populations of “helper” cells in the brain, called astrocytes, plays a specific role in directing the formation of connections among neurons needed for learning and forming new memories.

31 Jul 2019

Use of broad-spectrum antibiotics to treat pneumonia does more harm than good

A new study by researchers at Intermountain Healthcare has found that administering broad-spectrum antibiotics, which act against a wide range of disease-causing bacteria, to treat patients with pneumonia often does more harm than good.

31 Jul 2019

Coffee intake after elective laparoscopic colorectal surgery leads to faster recovery of bowel function

Researchers from Switzerland evaluated the effect of standardized coffee intake on postoperative bowel movement after elective laparoscopic colorectal resection. This was a prospective randomized controlled trial conducted between September 2014 and December 2016.

31 Jul 2019

Antimicrobial peptides that help protect against infection defend against cancer

An antimicrobial agent called Defensin kills tumor cells and shrinks tumor size in fruit flies, with help from a pathway that flags the cells for destruction.

31 Jul 2019

Astrocytic MORs in the hippocampus responsible for conditioned place preference

If somebody asks me "are you a coffee addict?" I may say, "Yeah it seems like, but on the one condition, only in my office." I don't have that much craving for coffee at home, but just being in the office, where I used to drink coffee all the time seeking to get caffeine jitters, seems to trigger my caffeine-addicted brain.

31 Jul 2019

Regular physical activity in childhood linked to higher lung-function values in adolescent girls

Physical activity has many well-known health benefits, but its association with lung function in childhood and adolescence is not well understood.

31 Jul 2019

New synthetic approach would facilitate development of medicine and agrochemicals

A group of Japanese researchers mainly from Tokyo University of Agriculture and Technology (TUAT) and Hokkaido University drastically enhanced and sped up the way to skeletally diverse indole alkaloids, composed of the medicinally-relevant scaffolds.

31 Jul 2019

Study reports combination therapy using two nanoparticles to treat massive hemorrhage

Massive hemorrhage, or excessive bleeding, is a potentially preventable yet a major cause of death in trauma patients.

31 Jul 2019

Traditional measures overlook socioeconomic costs associated with dementia

A new research review highlighting the hidden costs of dementia suggests that traditional measures only show the 'tip of the iceberg' of the cost impact on society.

31 Jul 2019

Study investigates whether patients with ADPKD should be screened for brain aneurysms

Autosomal dominant polycystic kidney disease is characterized by progressive development of kidney cysts, as well as abnormalities outside the kidneys, including brain aneurysms or weaknesses in blood vessels in the brain that balloon and fill with blood and may later rupture.

31 Jul 2019

Less-invasive procedures for critical limb ischemia as good as more invasive open surgeries

Less-invasive procedures to open severely-clogged leg arteries were as good at helping people survive and avoid amputation as more invasive open surgeries, according to a study reported in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

31 Jul 2019

New MRI can record changes in biological makeup of brain tissue

MRI's give us a picture of our body's insides—organs, bones, nerves and soft tissue. But what if MRI's could show us the molecular makeup of our body parts, and help doctors more quickly determine the onset of disease and begin treatment?

31 Jul 2019

Study discovers paradoxical proinflammatory effect of endocannabinoids in the brain

A new study led by the Neuropharmacology Laboratory -NeuroPhar at UPF shows that increasing endocannabinoids in the brain may cause inflammation in specific brain areas such as the cerebellum, which is associated with problems of fine motor coordination.

30 Jul 2019

Insecticide-treated bed net use is higher during rainy season, study finds

The more rainfall a region in sub-Saharan Africa gets, the more mosquitoes proliferate there and the more likely its residents will sleep under their insecticide-treated bed nets to prevent malaria transmission, a new study from the Johns Hopkins Center for Communication Programs suggests.

30 Jul 2019

Medical Research News

Antenatal renal pelvis dilatation increases risk of hospital admissions in early childhood

Brand–brand competition unlikely to lower list prices of brand-name drugs

Preventing parasites from adhering to mosquito guts could stop disease transmission

International collaborative pinpoints key areas to catalyze nutrition-based cancer prevention

Genetic and environmental factors play major roles in the onset of vitiligo

Autonomic nervous system of babies functions well regardless of mode of delivery, study finds

Johns Hopkins researchers use nanotechnology to repair faulty brain circuits

Use of broad-spectrum antibiotics to treat pneumonia does more harm than good

Coffee intake after elective laparoscopic colorectal surgery leads to faster recovery of bowel function

Antimicrobial peptides that help protect against infection defend against cancer

Astrocytic MORs in the hippocampus responsible for conditioned place preference

Regular physical activity in childhood linked to higher lung-function values in adolescent girls

New synthetic approach would facilitate development of medicine and agrochemicals

Study reports combination therapy using two nanoparticles to treat massive hemorrhage

Traditional measures overlook socioeconomic costs associated with dementia

Study investigates whether patients with ADPKD should be screened for brain aneurysms

Less-invasive procedures for critical limb ischemia as good as more invasive open surgeries

New MRI can record changes in biological makeup of brain tissue

Study discovers paradoxical proinflammatory effect of endocannabinoids in the brain

Insecticide-treated bed net use is higher during rainy season, study finds

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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