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Researchers identify new therapeutic targets for kidney fibrosis

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population--and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis.

29 Jan 2019

USC researchers use AI to identify blood-based markers of Alzheimer's disease

Nearly 50 million people worldwide have Alzheimer's disease or another form of dementia. While age is the greatest risk factor for developing the disease, researchers believe most Alzheimer's cases occur as a result of complex interactions among genes and other factors. But those factors and the role they play are not known--yet.

29 Jan 2019

First precision medicine trial in lung cancer expands to include more patients

The Lung Cancer Master Protocol, the first precision medicine trial in lung cancer supported by the National Cancer Institute, part of the National Institutes of Health, is undergoing a major expansion to include patients with all non-small cell lung cancers -- which make up about 85 percent of all lung cancer diagnoses in the U.S.

29 Jan 2019

Hospital patients' poor food intake is putting their health and lives at risk, study shows

For the 36 million Americans hospitalized each year, adequate nutrition plays a critical role in their health and recovery. Yet research from nutritionDay in the U.S., in collaboration with Abbott, shows malnutrition is still an unaddressed and widespread problem in hospitals.

29 Jan 2019

Cells in the intestines play key role in inducing acute inflammatory episodes

Medical researchers discover a type of cell which induces acute inflammatory episodes in bowel diseases.

29 Jan 2019

CHOP physician-researchers analyze opioid prescription patterns in children

As the opioid epidemic continues to plague the United States, physician-researchers at Children's Hospital of Philadelphia analyzed prescription patterns in children.

29 Jan 2019

Experts highlight emerging evidence of impending Parkinson’s disease pandemic

For most of human history Parkinson's disease (PD) has been a rare disorder. However, demography and the by-products of industrialization a now contributing to an impending a Parkinson's pandemic, according to experts writing in a supplement to the Journal of Parkinson's Disease.

29 Jan 2019

Breast cancer patients at increased risk of atrial fibrillation

A new study has shown that patients with breast cancer may be at an increased risk of developing the heart condition atrial fibrillation (AF).

29 Jan 2019

New research shows adult neurogenesis does not persist in the human hippocampus

The generation of new neurons in the human hippocampus strongly decreases from childhood to almost undetectable levels in adults. It can therefore be stated that neurogenesis in the human hippocampus is almost non-existent, as opposed to what has been thought in recent decades.

29 Jan 2019

Researchers identify effects of nanoparticles on intestinal microorganisms

The intestinal microbiome is not only key for food processing but an accepted co-determinant for various diseases. Researchers led by the University Medical Center of Johannes Gutenberg University Mainz identified effects of nanoparticles on intestinal microorganisms.

29 Jan 2019

Augmentation of labor with higher doses of oxytocin does not reduce rate of cesarean sections

Delayed labor increases the risk of a cesarean section, even among women who receive oxytocin for augmentation of labor. The rate of cesarean section among first-time mothers is not reduced if the administered dose is doubled either, according to a dissertation from Sahlgrenska Academy at the University of Gothenburg, Sweden.

29 Jan 2019

Columbia neuroengineers create new system to translate thoughts into speech

In a scientific first, Columbia neuroengineers have created a system that translates thought into intelligible, recognizable speech. By monitoring someone's brain activity, the technology can reconstruct the words a person hears with unprecedented clarity.

29 Jan 2019

An engineered virus selectively targets and kills cancer cells

An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers.

29 Jan 2019

Binge and heavy drinking may change DNA, resulting in greater desire for alcohol

Binge and heavy drinking may trigger a long-lasting genetic change, resulting in an even greater craving for alcohol, according to a Rutgers-led study in the journal Alcoholism: Clinical & Experimental Research.

29 Jan 2019

Megaphages detected in the intestinal tract of humans who eat high-fiber, low-fat diet

Viruses plague bacteria just as viruses like influenza plague humans. Some of the largest of these so-called bacteriophages have now been found in the human gut, where they periodically devastate bacteria just as seasonal outbreaks of flu lay humans low, according to a new study led by University of California, Berkeley, scientists.

29 Jan 2019

Researchers compare treatment options for fecal incontinence

It is a common health problem that causes uncommon personal discomfort. Fecal incontinence, or accidental stool leakage, affects some 8 to 10 percent of the 325 million people in the United States. In up to half of patients, there is both fecal and urinary incontinence.

29 Jan 2019

Study adds more evidence to the link between hearing loss and cognitive decline

Hearing loss affects tens of millions of Americans and its global prevalence is expected to grow as the world's population ages. A new study led by investigators at Brigham and Women's Hospital adds to a growing body of evidence that hearing loss is associated with higher risk of cognitive decline.

29 Jan 2019

Brexit could increase risk of cardiovascular disease

Brexit could contribute to thousands more deaths from heart attacks and strokes by 2030, new research has found.

29 Jan 2019

New study elucidates role of signaling molecule in development of myocarditis

Researchers of Ludwig-Maximilians-Universitaet in Munich have shown that a protein called midkine, a member of the class of signaling molecules known as cytokines, is a key driver of inflammation in the heart muscle that can lead to heart failure in patients with myocarditis.

29 Jan 2019