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Early immune system changes contribute to lung damage in cystic fibrosis

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the disease causes changes in the immune system early in life, presumably even in newborns.

7 Feb 2025

Alcohol and preexisting health conditions raise risk of advanced liver disease

Why do some people who consume a few glasses of alcohol a day develop advanced liver disease while others who drink the same amount don't?

7 Feb 2025

Comprehensive atlas of endothelial cells advances diabetes research

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas have been notoriously difficult to study, but Weill Cornell Medicine investigators have now succeeded in comprehensively detailing the unique characteristics of these cells.

7 Feb 2025

Cancer incidence and deaths still higher in Appalachia despite progress

Fewer people than before are being diagnosed with and dying from cancer in Appalachia, but cancer incidence and death rates remain substantially higher, especially in certain areas of Central Appalachia, compared to elsewhere in the U.S.

7 Feb 2025

Fear of cancer recurrence disrupts many aspects of breast cancer survivors' lives

Breast cancer is the world's most prevalent cancer. Although earlier detection and targeted treatment have resulted in high survival rates, many breast cancer survivors experience fear of cancer recurrence. For some survivors this fear is occasional, for others it is persistent and often debilitating.

7 Feb 2025

ASU researchers propose a unifying explanation for molecular chaos driving Alzheimer's disease

In a groundbreaking theory, scientists at Arizona State University's Biodesign Institute propose a unifying explanation for the molecular chaos driving Alzheimer's disease.

6 Feb 2025

Dispensary warning signs about cannabis use during pregnancy found ineffective

Warning signs at dispensaries about the potential health effects of cannabis use in pregnancy may not be effective, according to a new report in the Journal of Studies on Alcohol and Drugs, based at Rutgers University.

6 Feb 2025

Adrenomedullin hormone contributes to insulin resistance in obesity-associated type 2 diabetes

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.

6 Feb 2025

Childhood and adult trauma may play a role in endometriosis pathogenesis

The University of Barcelona has participated in an international study that has found new evidence linking traumatic experiences and stressful events with endometriosis, a chronic systemic inflammatory disease characterized by the presence of endometrial-like tissue outside the uterus.

6 Feb 2025

Are school takeaway bans just a policy illusion? Students say yes

Most young people are unaware of takeaway exclusion zones near schools, and policies limiting new outlets fail to address unhealthy food access from convenience stores and delivery apps.

6 Feb 2025

Researchers uncover brain mechanisms that help overcome instinctive fears

Researchers at the Sainsbury Wellcome Centre (SWC) at UCL have unveiled the precise brain mechanisms that enable animals to overcome instinctive fears.

6 Feb 2025

Dysregulation of RNA-binding proteins in rheumatoid arthritis and osteoarthritis

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of RNA-binding proteins (RBPs), which are critical for alternative mRNA splicing and translational control in rheumatoid arthritis (RA).

6 Feb 2025

Can parents' diet predict childhood obesity? New research weighs in

Children’s eating habits are strongly influenced by their parents' weight status, with those having overweight or obese parents consuming more carbohydrates and exhibiting higher obesity risks.

6 Feb 2025

Neoantigen vaccine sparks powerful immune defense against kidney cancer

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to long-lasting T cell expansion and no disease recurrence after 40 months.

6 Feb 2025

GPT-4 gives physicians an edge in complex case management

A new study shows that GPT-4 enhances physicians’ management reasoning, improving clinical decision-making beyond conventional resources.

6 Feb 2025

Research unveils synergistic effects of tau and beta-amyloid in Alzheimer's

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's-tau protein and beta-amyloid-affect brain circuits in distinct yet synergistic ways, particularly those linked to memory and emotions.

6 Feb 2025

Fruit fly research uncovers brain signals behind alcohol-induced insomnia

Alcohol use disorder, which affects over 10% of Americans, can lead to persistent and serious insomnia. Difficulties falling asleep and staying asleep can last even after months of sobriety, increasing the risk of relapse.

6 Feb 2025

New method for detecting inflammation could revolutionize disease diagnosis

Nearly every disease has an inflammatory component, but blood tests can't pinpoint inflammation in specific organs or tissues in the human body.

6 Feb 2025

New study identifies potential drug targets for heart failure

Heart failure remains a substantial burden for patients due to its high prevalence and limited therapeutic options. Heart failure is classified into two major clinical subtypes- heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF).

6 Feb 2025

Brazilian study reveals new pathways for preventing atrial fibrillation

A recent Brazilian study published in Nature Cardiovascular Research has highlighted promising pathways for preventing and treating atrial fibrillation, a condition that significantly raises the risks of stroke and dementia.

6 Feb 2025