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Engineer to develop drug-filled hydrogel to repair the damaged heart

After a heart attack, the cells in the heart muscle cannot get enough nutrients and oxygen to survive, so they die. A structural support network in the heart's wall can help those cells regenerate, however, two enzymes that break down the network are naturally increased after a heart attack, leaving the heart in a fight for its life.

28 Feb 2019

Protein content of tumors correlates with treatment response and survival in glioma patients

Brain tumors vary widely in how they respond to treatment. However, early assessment of therapy response is essential in order to choose the best possible treatment for the patient.

28 Feb 2019

Research provides evidence for greater reliance on terrestrial bipedalism by human ancestors

The oldest distinguishing feature between humans and our ape cousins is our ability to walk on two legs - a trait known as bipedalism. Among mammals, only humans and our ancestors perform this atypical balancing act.

28 Feb 2019

Scientists shed light on the history of Zika virus in Thailand

The circulation of the dengue virus for the past sixty years in South-East Asia is relatively well known. For Zika, the situation is much less clear.

28 Feb 2019

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers.

28 Feb 2019

Extra weekend sleep cannot repair the damage from sleep-deprived work week

Think sleeping in on the weekend can repair the damage from a week of sleepless nights? Not so, according to University of Colorado Boulder research published today in Current Biology.

28 Feb 2019

Pesticides, other environmental pollutants advance progression of ALS

While exact causes of amyotrophic lateral sclerosis (ALS) remain unknown, new research shows pesticides and other environmental pollutants advance the progression of the neurodegenerative disease.

28 Feb 2019

Healthy premature babies can succeed at breastfeeding, shows study

Researchers have determined that healthy premature babies can have as much success breastfeeding as full-term babies.

28 Feb 2019

Stress controllability mitigates the negative effects

In individuals, stress exposure in adolescence increases vulnerability and risk of developing psychopathologies in adulthood, such as drug addiction, mood, anxiety, addiction to gambling, attention deficit hyperactivity disorder, etc.

28 Feb 2019

Prenatal vitamins may reduce the risk of autism in high-risk families

Researchers have found that mothers of children with autism may be able to reduce the risk of autism in further offspring by taking prenatal vitamins.

28 Feb 2019

Researchers reveal promising biomarker for vascular disease relapse

Researchers at Okayama University report in the journal Arthritis & Rheumatology that monitoring a particular antigen can be used for predicting relapse of the vascular disease AAV.

28 Feb 2019

Exposure to antenatal corticosteroid therapy associated with reduced fetal growth

Infants exposed to antenatal corticosteroid therapy to accelerate lung maturation have a clinically significant reduction in birth size, according to a new of study of 278,508 births published this week in PLOS Medicine by Alina Rodriguez of the University of Lincoln and Imperial College London, UK, and colleagues.

28 Feb 2019

Lactose-free, reduced-carbohydrate milk does not improve outcomes in severely malnourished children

Treating hospitalized, severely malnourished children with a lactose-free, reduced-carbohydrate milk formula does not improve clinical outcomes, according to a study published February 26 in the open-access journal PLOS Medicine by Robert Bandsma of the Hospital for Sick Children in Toronto, Canada, James Berkley of the KEMRI/Wellcome Trust Research Programme in Kilifi, Kenya, and colleagues.

28 Feb 2019

Infants born with heart defects more likely to develop heart problems later in life

An infant born with a relatively simple heart defect is far more likely to develop heart problems as an adult, researchers at the Stanford University School of Medicine have discovered.

28 Feb 2019

Research on health effects of alcohol consumption may underestimate the risks for younger people

Studies of health effects of alcohol consumption may underestimate the risks of imbibing, particularly for younger people, according to a new study in the Journal of Studies on Alcohol and Drugs.

28 Feb 2019

Study elucidates mechanism behind development of steroid diabetes

Steroids are used for treating various diseases such as allergic disorders, but they occasionally cause adverse effects, such as steroid diabetes and other metabolic disturbances. Since steroids act throughout the body, how these adverse effects are caused and by which organ are not well understood.

28 Feb 2019

Personalized therapy for aggressive brain cancer shows potential

Advances in genetics and genomics have taught us that every single tumor is different, and yet most standard therapies treat them all in the same way, limiting the effectiveness of treatments offered to many cancer patients.

28 Feb 2019

Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Crigler-Najjar syndrome affects about one in a million people at birth. Because of a defective gene, these individuals lack an essential enzyme in their liver to eliminate bilirubin, a toxic bile pigment that accumulates in all body tissues causing jaundice and potentially leading to irreversible and lethal neurological damage.

28 Feb 2019

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in muscle formation¾in five of the tumors.

28 Feb 2019

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma, the most common esophageal malignancy in the United States, according to new research out of Case Western Reserve University School of Medicine.

28 Feb 2019

Medical Research News

Engineer to develop drug-filled hydrogel to repair the damaged heart

Protein content of tumors correlates with treatment response and survival in glioma patients

Research provides evidence for greater reliance on terrestrial bipedalism by human ancestors

Scientists shed light on the history of Zika virus in Thailand

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Extra weekend sleep cannot repair the damage from sleep-deprived work week

Pesticides, other environmental pollutants advance progression of ALS

Healthy premature babies can succeed at breastfeeding, shows study

Stress controllability mitigates the negative effects

Prenatal vitamins may reduce the risk of autism in high-risk families

Researchers reveal promising biomarker for vascular disease relapse

Exposure to antenatal corticosteroid therapy associated with reduced fetal growth

Lactose-free, reduced-carbohydrate milk does not improve outcomes in severely malnourished children

Infants born with heart defects more likely to develop heart problems later in life

Research on health effects of alcohol consumption may underestimate the risks for younger people

Study elucidates mechanism behind development of steroid diabetes

Personalized therapy for aggressive brain cancer shows potential

Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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