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Targeting mossy cells may offer new strategy for treating brain disorders

A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders, according to a study from scientists at the University of North Carolina School of Medicine.

27 Jul 2018

Newer version of ALS drug may effectively treat inherited form of the disease

NIH-funded researchers delayed signs of amyotrophic lateral sclerosis in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1.

27 Jul 2018

Researchers identify genes linked to childhood nephrotic syndrome

Childhood nephrotic syndrome is the most frequently occurring chronic kidney disease among children. A Japanese research team has identified a group of genes that are strongly related to the development of childhood nephrotic syndrome.

27 Jul 2018

Research provides new insights about when booster meningitis vaccines are needed

Scientists are indicating that children in Burkina Faso who were vaccinated against group A meningococcal meningitis and septicemia between the ages of 1-4 years in 2010, could need a booster dose of the vaccine as early as this year to ensure they remain protected.

27 Jul 2018

Bile acids from the gut may offer new treatment for cocaine abuse

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb Flynn of Vanderbilt University, Aurelio Galli of the University of Alabama at Birmingham, and colleagues.

27 Jul 2018

Mosquito screening found to be useful for tracking recurrence of lymphatic filariasis

To ensure elimination of the Wuchereria bancrofti, a parasitic roundworm that causes lymphatic filariasis, public health workers must follow up mass drug administration with careful monitoring for recurrence.

27 Jul 2018

Qualification of first Parkinson's biomarker represents major milestone in clinical trials

The biomarker is used to determine the presence of dopamine transport deficiency in the brain, and has been qualified as an enrichment biomarker for clinical trials targeting early stages of Parkinson's, soon after diagnosis

27 Jul 2018

Researchers discover new protein that controls level of inflammation-inducing molecule

One of the major therapeutic targets for inflammatory diseases is the inflammation-inducing molecule TNF. However, excess levels of TNF cause side effects and can lead to diseases.

27 Jul 2018

Nucleic acid nanoparticles found to have varying immune responses

An extensive experiment testing the immune effects of a broad group of lab-designed nucleic acid nanoparticles did not find a strong, uniform immune response, as had been predicted.

27 Jul 2018

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Researchers have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder.

27 Jul 2018

Scientists take important step to understand mechanisms that cause Huntington's disease

The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease.

27 Jul 2018

Study shares public views of using gene editing to change unborn baby’s genetic makeup

A majority of Americans support the idea of using gene editing with the goal of delivering direct health benefits for babies.

27 Jul 2018

Eliminating malaria-carrying mosquitoes does not impact ecosystem, shows study

By combining studies on one species of malaria-carrying mosquito, researchers found that no other animals rely solely on them for food.

27 Jul 2018

Researchers investigate how afferent nerves that sprout from the ectopic ear reach the brain

In vertebrates, the inner ear develops from the otic placode, a group of cells found in a specific region on the surface of the growing embryo.

27 Jul 2018

Study shows spillover effect of evidence-based opioid prescribing for major procedures

To curb the use of opioids after major elective operations and prevent these pain relievers from falling into the wrong hands, surgeons at the University of Michigan developed prescribing recommendations based on published medical evidence for one operation, gall bladder removal, and then discovered a spillover effect that led them to prescribe roughly 10,000 fewer pills for other major operations, according to study results appearing as an "article in press" on the website of the Journal of the American College of Surgeons ahead of print.

27 Jul 2018

Medical Research News

Targeting mossy cells may offer new strategy for treating brain disorders

Newer version of ALS drug may effectively treat inherited form of the disease

Researchers identify genes linked to childhood nephrotic syndrome

Research provides new insights about when booster meningitis vaccines are needed

Bile acids from the gut may offer new treatment for cocaine abuse

Mosquito screening found to be useful for tracking recurrence of lymphatic filariasis

Qualification of first Parkinson's biomarker represents major milestone in clinical trials

Researchers discover new protein that controls level of inflammation-inducing molecule

Nucleic acid nanoparticles found to have varying immune responses

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Scientists take important step to understand mechanisms that cause Huntington's disease

Study shares public views of using gene editing to change unborn baby’s genetic makeup

Eliminating malaria-carrying mosquitoes does not impact ecosystem, shows study

Researchers investigate how afferent nerves that sprout from the ectopic ear reach the brain

Study shows spillover effect of evidence-based opioid prescribing for major procedures

Brain's response to taste stimuli could play role in driving anorexia nervosa

Preoperative opioid consumption is strongest risk factor for prolonged opioid use, shows study

Pilot study uses naturalistic driving approach to examine self-regulation behavior of older adults with AD

New study aims to analyze potential health benefits of forests on humans

Discovery of two molecules could pave way for new drugs to treat traumatic brain injury

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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