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New study explores obecabtagene autoleucel for adults with hard-to-treat leukemia

FELIX study results reveal obe-cel's potential in relapsed B-cell ALL, achieving 77% remission with low severe toxicity, enhancing CAR T-cell therapy outcomes.

2 Dec 2024

Visceral fat found to contribute to Alzheimer's disease development

Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

2 Dec 2024

Engineered stone countertop workers at risk for silicosis

Durable and attractive, engineered stone countertops are a popular feature in modern American kitchens, but the workers who build them are risking their health.

2 Dec 2024

Natural proteins may offer new way to treat covid-19 and autoimmune disorders

Some people naturally have higher levels of proteins that protect them from covid-19. New studies at Umeå University of our immune system may pave the way for more personalized treatments of both covid-19 and autoimmune disorders.

2 Dec 2024

Higher plant-based protein intake linked to lower heart disease risk

Eating a diet with a higher ratio of plant-based protein to animal-based protein may reduce the risk of cardiovascular disease (CVD) and coronary heart disease (CHD), according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

2 Dec 2024

Lung cancer screening with CT can identify coronary artery calcium

Lung cancer screening with low-dose chest computed tomography (CT) may detect more than just lung cancer. As new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.231602 shows, these CTs can identify coronary artery calcium, a strong risk factor for coronary artery disease (CAD), in patients without cardiac symptoms.

2 Dec 2024

ARMC5 regulates saturated and unsaturated fatty acid levels in fat cells

Researchers at Osaka University identified a degradation factor for SREBP1 as essential for maintaining the balance of saturated and unsaturated fatty acids in adipose tissue.

2 Dec 2024

Gut transit time and pH shape microbiome individuality and dietary responses

Scientists reveal gut transit time and pH as key drivers of microbiome and metabolic individuality, paving the way for personalized dietary strategies.

1 Dec 2024

Can beef fit in a heart-healthy diet? Review provides new insights

A systematic review suggests unprocessed beef has minimal impact on cardiovascular health markers.

1 Dec 2024

Heart health benefits soar with regular sleep schedules, research finds

Irregular sleep patterns significantly increase the risk of major adverse cardiovascular events (MACE), with higher sleep regularity associated with reduced cardiovascular risks. This large UK Biobank study underscores the need to prioritize sleep regularity in public health and clinical guidelines.

1 Dec 2024

Men face sharper brain aging from obesity and heart risks

Obesity and cardiovascular risk factors accelerate brain volume loss, with males experiencing earlier and more significant impacts, highlighting the importance of early interventions to prevent neurodegeneration.

1 Dec 2024

Capsule sponge test revolutionizes GERD diagnosis, reduces unnecessary endoscopies

Capsule sponge testing, a minimally invasive diagnostic tool, effectively triages gastroesophageal reflux disease (GERD) patients, reducing unnecessary endoscopies by 70% and accurately identifying high-risk cases for Barrett’s esophagus and cancer in real-world clinical settings.

1 Dec 2024

Star power eclipses science in obesity discussions on social media

Celebrity tweets about obesity and weight loss attract far more positive engagement than those from medical authorities, underscoring their potential as powerful health messengers.

1 Dec 2024

Neural connectivity predicts deep brain stimulation success in essential tremor

Study unveils how specific cortico-thalamic connectivity patterns influence essential tremor suppression with deep brain stimulation (DBS). It highlights the contralateral thalamus as a pivotal driver of tremor modulation and potential pathways for enhanced intervention strategies.

1 Dec 2024

Fibroblastic reticular cells power immune defenses in lung cancer

Fibroblastic reticular cells (FRCs) create T-cell-supportive niches within lung cancer tumors, facilitating T-cell migration, clustering, and activation. This study highlights FRCs' potential as therapeutic targets to boost anti-tumor immunity in non-small cell lung cancer (NSCLC).

1 Dec 2024

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

Study highlights the safety and early bactericidal activity of quabodepistat when combined with delamanid, bedaquiline, or both, offering potential for shorter and more tolerable tuberculosis treatment regimens.

1 Dec 2024

Systemic barriers hold back diverse talent in academic medicine

A JAMA Network Open study reveals persistent inequities in academic medicine, where women and racial/ethnic minority physicians face significant barriers to promotions. These disparities, rooted in systemic biases, highlight the urgent need for reforms in recruitment and evaluation processes.

1 Dec 2024

Reinstating masking curbs hospital viral outbreaks, study confirms

Researchers investigate how changes in hospital policies for SARS-CoV-2 testing and masking have influenced hospital-acquired respiratory viral infections.

1 Dec 2024

Ultra-processed foods increase active psoriasis risk, study shows

This study highlights a significant link between high ultra-processed food (UPF) consumption and active psoriasis, independent of BMI and other factors. The findings emphasize UPFs' contribution to proinflammatory pathways in individuals with this chronic skin condition.

1 Dec 2024

Covid-19 may raise risk of developing multiple sclerosis

Covid-19 may be a risk factor for multiple sclerosis (MS). This has been shown by new research at örebro University and örebro University Hospital, Sweden.

29 Nov 2024