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SLU scientist describes several tactics that can help cells overcome lesions

In a recent review paper published in Nature Structural & Molecular Biology, SLU scientist Alessandro Vindigni, Ph.D., describes the strategies cells use when their DNA faces replication stress, challenges that may derail a cell's ability to reproduce.

29 Mar 2016

Structure of fibril protein could lead to specific targets for diagnosis, treatment of Parkinson's disease

Chemists have identified the complex chemical structure of the protein that stacks together to form fibrils in the brains of Parkinson's disease patients. Armed with this knowledge, researchers can identify specific targets for diagnosis and treatment.

29 Mar 2016

UCI researchers get $8 million to help develop new vaccine for Q fever

A University of California, Irvine scientific team led by infectious diseases researchers Philip Felgner and Aaron Esser-Kahn has received $8 million from the U.S. Department of Defense's Defense Threat Reduction Agency to help develop a new vaccine for Q fever.

29 Mar 2016

Lack of ARHGAP33 molecule causes neuropsychiatric disorders-related abnormal higher brain functions

A research group led by Osaka University and the University of Tokyo found that the intracellular protein trafficking is important for higher brain functions such as learning and memory. The research group showed that a molecule, ARHGAP33 regulates synaptic functions and behaviors via intracellular protein trafficking and that the lack of ARHGAP33 causes neuropsychiatric disorder-related impaired higher brain functions.

29 Mar 2016

Gleevec could be novel therapeutic agent for type 2 diabetes

The cancer treatment drug Imatinib, otherwise known as Gleevec is approved to treat various forms of cancer, mostly notably chronic myeloid leukemia (CML). However, researchers have stumbled onto another possible use for it, curing type 2 diabetes.

28 Mar 2016

High-throughput RNA interference screen identifies potential drug target against henipaviruses

The closely related Hendra and Nipah viruses (referred to jointly as henipaviruses) are deadly cousins of the more common mumps, measles, and respiratory syncytial viruses, all members of the paramyxovirus family. Henipavirus outbreaks are on the rise, but little is known about them, partly because research has to be conducted under extreme level containment conditions.

28 Mar 2016

BIDMC investigators identify precise 5-gene classifier for discriminating early pancreatic cancer

Pancreatic cancer, the fourth leading cause of cancer death in the United States, is often diagnosed at a late stage, when curative treatment is no longer possible. A team led by investigators at Beth Israel Deaconess Medical Center has now identified and validated an accurate 5-gene classifier for discriminating early pancreatic cancer from non-malignant tissue.

28 Mar 2016

Kevin Rudi Superhero 5K Fun Run to raise money for sarcoma research

The second annual Kevin Rudi Superhero 5K Fun Run will start and end by the Memorial Stadium Field House in Las Cruces. Money raised for sarcoma research will benefit The University of New Mexico Comprehensive Cancer Center.

28 Mar 2016

Outdoor workers in Europe at increased risk of developing non-melanoma skin cancer

There are almost 14.5 million workers in Europe, who spend at least 75% of their working time under the sun.

28 Mar 2016

Researchers demonstrate novel method for imaging engineered nanoparticles in tissues

As a testament to Governor Andrew Cuomo’s leadership in developing an unparalleled research and development ecosystem in New York State, Sara Brenner, MD, MPH and her colleagues at SUNY Polytechnic Institute (SUNY Poly), the George Washington School of Medicine and Health Sciences, and Stony Brook University have demonstrated a novel method for the rapid visualization and identification of engineered nanoparticles in tissues.

28 Mar 2016

Engineered HIV vaccine protein may prevent HIV infection

Some people infected with HIV naturally produce antibodies that effectively neutralize many strains of the rapidly mutating virus, and scientists are working to develop a vaccine capable of inducing such "broadly neutralizing" antibodies that can prevent HIV infection.

28 Mar 2016

Transient contractions could be new target for therapeutic intervention in urinary bladder dysfunction

Researchers at the University of Vermont College of Medicine have made a discovery that helps explain how we know when to empty our bladders and may lead to new therapeutic interventions for bladder dysfunction.

28 Mar 2016

Cancer patients who choose home-based palliative care tend to live longer

A large study from Japan found that cancer patients who died at home tended to live longer than those who died in hospitals. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings suggest that oncologists should not hesitate to refer patients for home-based palliative care simply because less medical treatment may be provided.

28 Mar 2016

Higher rates of breastfeeding, vaccination use cut ear infection in babies

In what would be considered good news for many parents a new study from The University of Texas Medical Branch at Galveston finds the rates of ear infections during a baby's first year have declined; the investigators suggested that higher rates of breastfeeding, use of vaccinations and lower rates of smoking may be the major contributors. The study was recently published in Pediatrics.

28 Mar 2016

Study finds combustible tobacco cigarettes cost less than e-cigarettes

Combustible tobacco cigarettes cost less to purchase than equivalent amounts of electronic cigarettes (e-cigarettes) in 44 of 45 countries sampled around the world, according to a new American Cancer Society study. The study, appearing in Tobacco Control, concludes the gap exists despite the fact that e-cigarettes are not yet widely subjected to comparable excise taxes as combustible cigarettes.

28 Mar 2016

Study reveals new hypothesis on evolution of hundreds of malaria species

A study published this week in the journal Molecular Phylogenetics and Evolution reveals a new hypothesis on the evolution of hundreds of species of malaria - including the form that is deadly to humans.

26 Mar 2016

First aid in the past could have present-day policy implications

A widespread knowledge of first aid once equipped millions of people to tackle emergencies ranging from a cut finger to a life-threatening seizure. Could a revival of these skills help reduce pressure on doctors' surgeries and NHS casualty departments?

26 Mar 2016

Study identifies genetic differences in kidney tumors of African-Americans

A University of North Carolina Lineberger Comprehensive Cancer Center-led study has identified genetic differences in tumors of African-Americans with the most common type of kidney cancer compared with whites.

26 Mar 2016

MGH study finds that the brains of young marijuana users react differently to social exclusion

A study from Massachusetts General Hospital researchers finds that the brains of young adult marijuana users react differently to social exclusion than do those of non-users. In a report published in the March issue of Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, the team reports that activation of the insula, a region of the brain that is usually active during social rejection, was reduced in young marijuana users when they were being excluded from participation in virtual game of catch.

26 Mar 2016

UC Berkeley biologists discover potential target for unisex contraceptives

UC Berkeley biologists have discovered the switch that triggers the power kick sperm use to penetrate and fertilize a human egg, uncovering a possible source of male infertility but also a potential target for contraceptives that work in both men and women.

26 Mar 2016

Medical Research News

SLU scientist describes several tactics that can help cells overcome lesions

Structure of fibril protein could lead to specific targets for diagnosis, treatment of Parkinson's disease

UCI researchers get $8 million to help develop new vaccine for Q fever

Lack of ARHGAP33 molecule causes neuropsychiatric disorders-related abnormal higher brain functions

Gleevec could be novel therapeutic agent for type 2 diabetes

High-throughput RNA interference screen identifies potential drug target against henipaviruses

BIDMC investigators identify precise 5-gene classifier for discriminating early pancreatic cancer

Kevin Rudi Superhero 5K Fun Run to raise money for sarcoma research

Outdoor workers in Europe at increased risk of developing non-melanoma skin cancer

Researchers demonstrate novel method for imaging engineered nanoparticles in tissues

Engineered HIV vaccine protein may prevent HIV infection

Transient contractions could be new target for therapeutic intervention in urinary bladder dysfunction

Cancer patients who choose home-based palliative care tend to live longer

Higher rates of breastfeeding, vaccination use cut ear infection in babies

Study finds combustible tobacco cigarettes cost less than e-cigarettes

Study reveals new hypothesis on evolution of hundreds of malaria species

First aid in the past could have present-day policy implications

Study identifies genetic differences in kidney tumors of African-Americans

MGH study finds that the brains of young marijuana users react differently to social exclusion

UC Berkeley biologists discover potential target for unisex contraceptives

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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