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Excess folic acid intake causes lowered immune function in aged mice

Previous studies have shown an association between high folic acid intake and a reduction in the immune system defenses needed to fight viral infections and cancer. In a new study in mice published in the Journal of Nutritional Biochemistry, scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University set out to determine if excess folic acid intake caused adverse changes in the immune system.

12 Jan 2016

Scientists discover protein interaction that describes aggressive subtype of medulloblastoma

Scientists at St. Jude Children's Research Hospital and the University of Würzburg in Germany have identified a protein interaction that is a hallmark of an aggressive subtype of medulloblastoma and that may provide a new treatment strategy.

12 Jan 2016

Researchers use quick screening method to identify, test promising anti-Ebola drugs

A quick screening method has been used for the first time in a standard open laboratory to identify and test promising anti-Ebola drugs. This approach increases the possibility of finding new therapies faster.

12 Jan 2016

MD Anderson signs collaborative research and development agreement with Enumeral

The University of Texas MD Anderson Cancer Center today announced that it has entered into a collaborative research and development agreement with Enumeral Biomedical Holdings Inc.

12 Jan 2016

McMaster University researchers take a giant leap in detecting early stages of leukemia

McMaster University researchers have taken a giant leap in identifying the early stages of a deadly cancer and predicting how it will develop in individuals.

11 Jan 2016

Cedars-Sinai researcher receives $2.5 million grant to develop risk assessment tool for sudden cardiac arrest

A Cedars-Sinai Heart Institute physician researcher has received a $2.5 million grant from the National Heart, Lung, and Blood Institute to develop a risk assessment tool that could identify patients susceptible to sudden cardiac arrest, a usually fatal heart rhythm malfunction.

11 Jan 2016

Docetaxel remains effective in prostate cancer even after treatment with androgen-deprivation therapy

A study presented at the 2016 Genitourinary Cancers Symposium shows that 40 percent of patients with castration-resistant metastatic prostate cancer (mCRPC) treated with docetaxel following abiraterone had at least 50 percent reduction in prostate specific antigen (PSA), demonstrating the activity of this drug sequencing.

11 Jan 2016

3 out of 4 young adults with stroke symptoms delay trip to hospital

Up to three hours after a person experiences the first symptom of a stroke is often referred to as the "golden window." That's the period of time doctors say is crucial for patients to get to a hospital to receive medical care in order to restore blood flow to the brain and minimize or reverse damage.

11 Jan 2016

BlueWind completes patient enrolment for Overactive Bladder study to support CE Mark submission

BlueWind Medical, developer of a wireless neuro-stimulation device to treat multiple clinical indications, such as back pain, peripheral neuropathic pain, incontinence (OAB), epilepsy, and more, announced today the completion of patient enrolment for an Overactive Bladder (OAB) study which is currently being conducted to support CE Mark submission.

11 Jan 2016

Sorrento, Karolinska Institutet partner to develop new NK cell-based therapies

Sorrento Therapeutics, Inc., an antibody-centric, clinical-stage biopharmaceutical company developing new treatments for cancer and other unmet medical needs, announced today that it has formed an exclusive partnership with the world-renowned Karolinska Institutet in Stockholm, Sweden, to perform cutting-edge immuno-oncology research and to develop new natural killer (NK) cell-based therapies.

11 Jan 2016

Researchers describe three cleaning procedures that effectively remove, disassemble α-Syn fibrils

Lewy bodies and Lewy neurites are found in the brains of Parkinson's disease (PD) patients. They consist primarily of fibrils of the protein alpha-synuclein (α-Syn), which self-assembles into fibrils in vitro. If introduced into the human body, these seeds can act as prions and trigger the formation of toxic protein deposits. Because α-Syn fibrils are often used in research, it is important that they are not accidentally transferred to humans or cell cultures.

11 Jan 2016

NIST chemist develops portable kit for recovering traces of chemical evidence

A chemist at the National Institute of Standards and Technology has developed a portable version of his method for recovering trace chemicals such as environmental pollutants and forensic evidence including secret graves and arson fire debris.

11 Jan 2016

Wistar Institute scientists use revolutionary method to block melanoma progression

Melanoma patients who receive treatment with targeted therapies experience an initial response that feels like a cure, but that early excitement is quickly dampened when patients relapse as their cancers find alternative pathways in our cells to grow and spread. With melanoma so good at escaping targeted treatments, there's a dire need to halt these cancers in their tracks to prolong good responses and promote longer, healthier lives.

11 Jan 2016

Genetic factors in puberty timing: an interview with Dr John Perry

The study focused on the genetic regions that influence age at voice breaking - a distinct developmental milestone that happens to young men as their larynx (voice box) lengthens when exposed to male hormones.

11 Jan 2016

Using skin cells to treat injured hearts

Following a heart attack or other heart trauma, the heart is unable to replace its dead cells. Patients are often left with little option other than heart transplants, which are rarely available, or more recently cell therapies that transplant heart cells into the patient's heart. In far too many cases, however, the transplanted heart cells do not engraft well, resulting in poor recovery.

11 Jan 2016

Finding may aid in the design of potential therapies for thyroid problems

Thyroid disease affects about 12 percent of the U.S. population. While many people with thyroid disease don't even know they have it, an overactive or underactive thyroid can cause a slew of problems, including weight gain or loss, mood changes and infertility. In children, an underactive thyroid can be fatal, which is why they are tested for a deficiency at birth.

11 Jan 2016

Study illuminates ways to better treat knee meniscus tears, other injuries

Fibrocartilage tissue in the knee is comprised of a more varied molecular structure than researchers previously appreciated, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania and the University of Delaware.

11 Jan 2016

Medical Research News

Excess folic acid intake causes lowered immune function in aged mice

Scientists discover protein interaction that describes aggressive subtype of medulloblastoma

Researchers use quick screening method to identify, test promising anti-Ebola drugs

MD Anderson signs collaborative research and development agreement with Enumeral

McMaster University researchers take a giant leap in detecting early stages of leukemia

Cedars-Sinai researcher receives $2.5 million grant to develop risk assessment tool for sudden cardiac arrest

Docetaxel remains effective in prostate cancer even after treatment with androgen-deprivation therapy

3 out of 4 young adults with stroke symptoms delay trip to hospital

BlueWind completes patient enrolment for Overactive Bladder study to support CE Mark submission

Sorrento, Karolinska Institutet partner to develop new NK cell-based therapies

Researchers describe three cleaning procedures that effectively remove, disassemble α-Syn fibrils

NIST chemist develops portable kit for recovering traces of chemical evidence

Wistar Institute scientists use revolutionary method to block melanoma progression

Genetic factors in puberty timing: an interview with Dr John Perry

Using skin cells to treat injured hearts

Finding may aid in the design of potential therapies for thyroid problems

Study illuminates ways to better treat knee meniscus tears, other injuries

Research could lead to new treatment for Rett Syndrome, other forms of autism

Blocking brain inflammation could protect against memory, behaviour changes

F-star signs agreement with AbbVie to discover, develop bispecific antibodies in immuno-oncology

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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