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Physicians may soon have new tool to closely track severity, potential spread of metastatic melanoma

Physicians treating patients with metastatic melanoma — one of the most aggressive forms of skin cancer — may soon have a superior tool in their efforts to closely track the disease.

12 Jan 2016

iCardiac provides industry-wide dataset access to enable broader validation of TQT alternative approach

iCardiac Technologies, Inc., a scientific leader in the conduct of cardiac safety assessments, today announced it is providing industry-wide access to its pivotal dataset as part of an effort announced by the Cardiac Safety Research Consortium to enable broader validation of an alternative approach to the Thorough QT (TQT) study.

12 Jan 2016

Drugs that block KDM4C and PRMT1 genes could be effective in treating AML

Two genes have been identified that are critical to the development of the biggest leukaemia killer, acute myeloid leukaemia (AML). Researchers at King’s College London found that drugs that selectively block these genes could be highly effective in treating this type of leukaemia.

12 Jan 2016

New article suggests that playing American football may contribute to hypertension

As National Football League playoff games are underway, a new article published in the "Hypotheses" section of the January 2016 issue of The FASEB Journal, suggests that the toll the sport takes on players' bodies extends beyond head trauma and damage to limbs and joints. The trauma and damage associated with football participation may also be linked to elevations in blood pressure through immune system activation and inflammation.

12 Jan 2016

Cancer concerns over chromium diet pills

Concerns have been raised over the long-term use of nutritional supplements containing chromium, after an Australian research team found the supplement is partially converted into a carcinogenic form when it enters cells.

12 Jan 2016

Synpromics, Cell Therapy Catapult to create stable producer cell lines for large-scale manufacture of viral vectors

Synpromics Ltd, a leading synthetic biology company, and The Cell Therapy Catapult, the UK organisation accelerating the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announce the launch of a collaboration to remove a major barrier to the development of the cell and gene therapy industry by reducing the cost and increasing the scale and efficiency of viral vector manufacturing.

12 Jan 2016

Higher-fat DASH diet significantly reduces blood pressure and triglycerides

The Dietary Approaches to Stop Hypertension (DASH) dietary pattern, which is high in fruits, vegetables and low fat dairy foods, significantly lowers blood pressure as well as low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol.

12 Jan 2016

New approach to package dual or more mixtures into a single capsule may boost drug efficiency

Researchers have developed a speedy, controllable way to get two or more ingredients into the same tiny capsule and only have them mix when triggered by a signal like vibrations or heat.

12 Jan 2016

Common painkiller diclofenac has significant anti-cancer properties

Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers from the Repurposing Drugs in Oncology project.

12 Jan 2016

UCA researchers create new animal models to study link between diabetes and Alzheimer's disease

In recent time, many epidemiological studies have proved very close links existing between diabetes and Alzheimer´s disease. In fact, it has been stated that diabetes is a significant risk factor for suffering from Alzheimer and vascular dementia, the two main causes of dementia.

12 Jan 2016

Study opens new door on the causes of vision issues in astronauts

Just when you think you've seen it all, our eyes look to be victims of a low-gravity environments, too. According to new research published in the January 2016 issue of The FASEB Journal, two significant genetic differences in enzymes that direct the one-carbon pathway of metabolism can affect astronaut vision.

12 Jan 2016

Discoveries could lead to development of novel therapies to prevent C. diff infection

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile ("C. diff") -- the leading cause of hospital-acquired diarrhea in the United States.

12 Jan 2016

Novel therapy may help in diagnosing, treating heart disease in humans

A novel therapy tested by University of Guelph scientists for treating a fatal heart disorder in dogs might ultimately help in diagnosing and treating heart disease in humans.

12 Jan 2016

GPR119 could be a potential treatment target for nonalcoholic fatty liver disease

New research published in the January 2016 issue of The FASEB Journal suggests that the G-protein-coupled receptor 119 (GPR119) could be a viable treatment target for nonalcoholic fatty liver disease. This receptor has already been identified as a drug target for diabetes and obesity, and this report raises hopes that compounds that target GPR119 for diabetes or obesity might also work for non-alcoholic fatty liver disease.

12 Jan 2016

Researchers take major step towards developing vaccine for river blindness

The world's first vaccine for a disease that causes misery for millions in Africa could be tested within five years.

12 Jan 2016

Novel anti-inflammatory agents could control hyper-inflammatory responses to fungal infection

The most frequent fungal threat to humans, Candida albicans, is a common cause oral and genital infection. The fungal infections are often worsened by overwhelming inflammatory responses in the body and cause high mortality among risk groups. Umeå University doctoral student Ava Hosseinzadeh has discovered two novel anti-inflammatory agents, an antioxidant and an anti-inflammatory molecule, which could be used to control the hyper-inflammatory responses to the fungal infection.

12 Jan 2016

Excess folic acid intake causes lowered immune function in aged mice

Previous studies have shown an association between high folic acid intake and a reduction in the immune system defenses needed to fight viral infections and cancer. In a new study in mice published in the Journal of Nutritional Biochemistry, scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University set out to determine if excess folic acid intake caused adverse changes in the immune system.

12 Jan 2016

Medical Research News

Physicians may soon have new tool to closely track severity, potential spread of metastatic melanoma

iCardiac provides industry-wide dataset access to enable broader validation of TQT alternative approach

Drugs that block KDM4C and PRMT1 genes could be effective in treating AML

New article suggests that playing American football may contribute to hypertension

Cancer concerns over chromium diet pills

Synpromics, Cell Therapy Catapult to create stable producer cell lines for large-scale manufacture of viral vectors

Higher-fat DASH diet significantly reduces blood pressure and triglycerides

New approach to package dual or more mixtures into a single capsule may boost drug efficiency

Common painkiller diclofenac has significant anti-cancer properties

UCA researchers create new animal models to study link between diabetes and Alzheimer's disease

Study opens new door on the causes of vision issues in astronauts

Discoveries could lead to development of novel therapies to prevent C. diff infection

Novel therapy may help in diagnosing, treating heart disease in humans

GPR119 could be a potential treatment target for nonalcoholic fatty liver disease

Researchers take major step towards developing vaccine for river blindness

Novel anti-inflammatory agents could control hyper-inflammatory responses to fungal infection

Excess folic acid intake causes lowered immune function in aged mice

Scientists discover protein interaction that describes aggressive subtype of medulloblastoma

Researchers use quick screening method to identify, test promising anti-Ebola drugs

MD Anderson signs collaborative research and development agreement with Enumeral

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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