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Berlin researchers use T cells to target mutations in cancer cells

The efficacy of the immune system to combat disease makes the body's own healing powers a promising approach in the fight against cancer. A Berlin research group led by Wolfgang Uckert, Thomas Blankenstein and Matthias Leisegang has been collaborating with U.S. researcher Hans Schreiber in a project to use immune components called T cells to target mutant proteins produced by cancer cells.

22 Feb 2016

UCLA-led researchers identify specific gene network that promotes repair in peripheral nervous system

Whether or not nerve cells are able to regrow after injury depends on their location in the body. Injured nerve cells in the peripheral nervous system, such as those in the arms and legs, can recover and regrow, at least to some extent. But nerve cells in the central nervous system -- the brain and spinal cord -- can't recover at all.

22 Feb 2016

New findings on gut microbiota to be discussed at 2016 Gut Microbiota for Health World Summit

Novel approaches for manipulating the gut microbiota through diet, pre- and probiotics, targeted antibiotic therapy and fecal microbiota transplantation for health maintenance and treatment are under investigation or already in use.

22 Feb 2016

Researchers examine impact of losing multiple senses on older adults

It's a well-known fact that aging can lead to losing one's senses: vision, smell, hearing, touch, and taste. In previous studies, researchers have learned about the consequences of experiencing a decline in a single sense. For example, losing senses of smell, vision, and hearing have all been linked to cognitive decline, poor mental health, and increased mortality.

22 Feb 2016

Calgary researchers develop new class of nanomedicines to treat autoimmune diseases

A new study from the University of Calgary could change the way researchers understand and treat autoimmune diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis.

22 Feb 2016

Dr. Elliot J. Androphy receives IGNITE grant to develop drug candidate for spinal muscular atrophy

Dr. Elliot J. Androphy, the Kampen-Norins Professor and chair of the Department of Dermatology at the Indiana University School of Medicine, has been awarded an IGNITE, or Innovation Grants to Nurture Initial Translational Efforts, grant by the National Institutes of Health.

22 Feb 2016

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Australian researchers have resolved a mystery about how a promising new class of anti-cancer drugs, called nutlins, work - paving the way for improving the future of cancer treatment.

22 Feb 2016

3-D map of critical protein could lead to new malaria vaccine

A three-dimensional 'map' of a critical protein that malaria parasites use to invade human red blood cells could lead to a vaccine countering the most widespread species of the parasite.

22 Feb 2016

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer's disease and improvements in monitoring the effects of medication.

22 Feb 2016

Researchers identify new group of powerful Ebola-fighting antibodies

A research team that included scientists from The Scripps Research Institute has identified a new group of powerful antibodies to fight Ebola virus.

22 Feb 2016

Penn researchers develop new mathematical model to estimate mutation rates in the human genome

It turns out that the type, how frequent, and where new mutations occur in the human genome depends on which DNA building blocks are nearby, found researchers from the Perelman School of Medicine at the University of Pennsylvania in an advanced online study published this week in Nature Genetics.

22 Feb 2016

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

Researchers have discovered that eliminating cells thought to aid tumor growth did not slow or halt the growth of cancer tumors. In fact, when the cancer-associated fibroblasts (CAFs), were eliminated after 10 days, the risk of metastasis of the primary tumor to the lungs and bones of mice increased dramatically.

22 Feb 2016

New article describes recent efforts made by researchers to classify bladder cancers

The ability to map the human genome has transformed how scientists and researchers classify various cancers. In the past, cancer cells were examined through a microscope and their appearance, often enhanced with dyes or other agents, was used to categorize the type of cancer.

22 Feb 2016

Patients benefit from one-on-one counseling session prior to knee or hip replacement surgery

A study at Hospital for Special Surgery finds that patients benefit from a one-on-one education session provided by a physical therapist and access to a custom web portal prior to knee or hip replacement surgery.

22 Feb 2016

New study focuses on safety of using induced pluripotent stem cells in patients

A new study led by scientists at The Scripps Research Institute and the J. Craig Venter Institute shows that the act of creating pluripotent stem cells for clinical use is unlikely to pass on cancer-causing mutations to patients.

22 Feb 2016

UGA scientists discover link between genetics and aging process

Scientists at the University of Georgia have shown that a hormone instrumental in the aging process is under genetic control, introducing a new pathway by which genetics regulates aging and disease.

22 Feb 2016

New discoveries provide further evidence for benefits of a good night's sleep

Why does sleeping on it help? This is the question tackled by new research at the University of Bristol, which reveals how brain activity during sleep sorts through the huge number of experiences we encounter every day, filing only the important information in memory.

22 Feb 2016

Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

Air pollution exposure increases obesity risk

Laboratory rats who breathed Beijing's highly polluted air gained weight and experienced cardio-respiratory and metabolic dysfunctions after three to eight weeks of exposure.

22 Feb 2016

Lenalidomide trials show potential for expanding lymphoma, leukaemia indications

Positive findings from two clinical trials have been published for the immunomodulatory agent lenalidomide in patients with heavily pretreated mantle cell lymphoma, and in adults with T-cell leukaemia-lymphoma or peripheral T-cell lymphoma.

19 Feb 2016

Medical Research News

Berlin researchers use T cells to target mutations in cancer cells

UCLA-led researchers identify specific gene network that promotes repair in peripheral nervous system

New findings on gut microbiota to be discussed at 2016 Gut Microbiota for Health World Summit

Researchers examine impact of losing multiple senses on older adults

Calgary researchers develop new class of nanomedicines to treat autoimmune diseases

Dr. Elliot J. Androphy receives IGNITE grant to develop drug candidate for spinal muscular atrophy

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

3-D map of critical protein could lead to new malaria vaccine

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

Researchers identify new group of powerful Ebola-fighting antibodies

Penn researchers develop new mathematical model to estimate mutation rates in the human genome

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

New article describes recent efforts made by researchers to classify bladder cancers

Patients benefit from one-on-one counseling session prior to knee or hip replacement surgery

New study focuses on safety of using induced pluripotent stem cells in patients

UGA scientists discover link between genetics and aging process

New discoveries provide further evidence for benefits of a good night's sleep

Researchers identify common molecular alteration in glioblastoma

Air pollution exposure increases obesity risk

Lenalidomide trials show potential for expanding lymphoma, leukaemia indications

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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