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Aberrant reward processing likely to precede bipolar symptom onset

Healthy children who have a parent with bipolar disorder show altered brain activation during reward processing, research shows.

28 Aug 2014

Gene variants linked to overactive bladder and prolapse in women

A systematic review and meta-analysis of genetic association studies reveals a number of genetic variations associated with overactive bladder and pelvic organ prolapse in women.

28 Aug 2014

Alpha-adrenergic treatment improves QoL in obese LUTS men

Alpha-adrenergic medication can significantly improve the quality of life of obese men with lower urinary tract symptoms, show study findings.

28 Aug 2014

Knee pain when using stairs early clue to OA

Feeling knee pain during weight-bearing activities involving knee bending, such as using stairs, could be an early sign of osteoarthritis and the need for intervention, research indicates.

28 Aug 2014

Bacteremia linked to worse in-hospital course, outcomes in patients with pneumonia

The presence of bacteremia in patients with pneumonia is associated with a worse in-hospital course of illness and poorer patient outcomes, show Spanish findings.

28 Aug 2014

High PD-L1 expression linked to reduced survival in NSCLC

Overexpression of programmed death-ligand 1 is independently associated with the presence of epidermal growth factor receptor gene mutations and poor prognosis in patients with non-small-cell lung cancer, Japanese researchers report.

28 Aug 2014

Risk-based treatment approach should be considered for patients with hypertension

Blood pressure-lowering treatment should target patients at greatest cardiovascular risk and not just those with the highest baseline levels, suggest findings of a meta-analysis.

28 Aug 2014

Reticular pseudodrusen predicts late-stage AMD

Reticular pseudodrusen increases the likelihood of people with choroidal neovascularisation in one eye also developing late-stage, age-related macular degeneration in the other eye, researchers report.

28 Aug 2014

Lifestyle factors modify vision impairment risk

Smoking, drinking alcohol and physical activity are modifiable behaviours that influence the risk of vision impairment, show findings from the Beaver Dam Eye Study.

28 Aug 2014

Central sclera thickening characterises dome-shaped macula

A dome-shaped macula appears to result from the relative thickening of the central macular sclera, researchers have found.

28 Aug 2014

Macular ischaemia, retinal thinning linked to reduced visual function in diabetic retinopathy

Macular ischemia and retinal thinning are associated with reduced visual function in patients with diabetic retinopathy, research suggests.

28 Aug 2014

Preoperative ultrasound reveals NSCLC chest wall invasion

Surgeon-performed ultrasound is a good alternative to computed tomography for the identification of chest wall invasion in patients with non-small-cell lung cancer, suggests research demonstrating 90% sensitivity for detection of the spread.

28 Aug 2014

Lifestyle intervention shows kidney benefits in diabetic patients

A lifestyle intervention focused on weight loss and increasing physical activity should be considered as additional treatment to prevent advanced kidney disease in overweight or obese people with Type 2 diabetes, say researchers.

28 Aug 2014

Millions of women suffering in silence with hot flashes

The steep decline in the use of hormone therapy has spawned a prevalent but preventable side effect: millions of women suffering in silence with hot flashes, according to a study by a Yale School of Medicine researcher and colleagues.

28 Aug 2014

Many people with severe rheumatoid arthritis failing to take expensive medication

Large numbers of people with severe rheumatoid arthritis are failing to take expensive medication as prescribed, according to a new multi-centre study led by researchers in Manchester.

From The University of Manchester 28 Aug 2014

Non-invasive functional neuroimaging tools help characterize how brain activity disrupted in dyslexia

A new study in Biological Psychiatry maps the circuitry of dyslexia. Dyslexia, the most commonly diagnosed learning disability in the United States, is a neurological reading disability that occurs when the regions of the brain that process written language don't function normally.

28 Aug 2014

Analysis reveals fascinating insights into client and therapist personalities and psychotherapy process

During this study in Psychotherapy Research, the authors set out to interpret the content and consequences of client's dreams about their therapists and vice versa. The analysis reveals some fascinating insights into client and therapist personalities, therapeutic relationships, and the psychotherapy process.

28 Aug 2014