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Familial hypercholesterolemia patients can benefit from alirocumab drug

Alirocumab lowers cholesterol in patients with heterozygous familial hypercholesterolemia to levels unreachable with statins alone, according to results from four ODYSSEY trials presented at ESC Congress today.

2 Sep 2015

Diagnosing traumatic brain injury through a blood test: an interview with Dr Korley

The severity of traumatic brain injury is currently crudely classified as mild, moderate or severe. However, often patients referred to as mild have debilitating symptoms that are not “mild”. Additionally, there are patients currently classified as moderate or severe who regain their pre-injury functional status whereas others don’t.

1 Sep 2015

Administering ticagrelor in the ambulance cuts ischaemic events 24 hours following PCI

Ticagrelor administered in the ambulance reduces ischaemic events 24 hours after primary percutaneous coronary intervention (PCI), according to findings from the ATLANTIC-H24 study presented for the first time today at ESC Congress.

1 Sep 2015

Men with relatively unaggressive prostate tumors unlikely to develop metastatic prostate cancer

Men with relatively unaggressive prostate tumors and whose disease is carefully monitored by urologists are unlikely to develop metastatic prostate cancer or die of their cancers, according to results of a study by researchers at the Brady Urological Institute at Johns Hopkins, who analyzed survival statistics up to 15 years.

1 Sep 2015

North Shore-LIJ researcher compares safety benefits two blood-thinning medications

A large, ambitious contrast of blood-thinning medications used during cardiac stent placement suggests that a very expensive drug offers no clear safety benefits over a much more affordable option, according to a prominent North Shore-LIJ researcher and cardiologist.

1 Sep 2015

New statistical model may help predict patients most likely to benefits from surgical treatment for mesothelioma

A new statistical model may help predict which patients are most likely to receive life-extending benefits from surgical treatment for malignant pleural mesothelioma (MPM), according to an article in the September 2015 issue of The Annals of Thoracic Surgery.

1 Sep 2015

Finerenone effective in heart failure patients with diabetes and/or chronic kidney disease

In heart failure patients with diabetes and/or chronic kidney disease, a new, non-steroidal mineralocorticoid receptor antagonist (MRA) called finerenone was no more effective than the currently approved MRA eplerenone in reducing the heart failure biomarker N-terminal pro-B-type natriuretic peptide [NT-proBNP].

1 Sep 2015

Defibrillator does not improve outcomes in patients with CRT pacemaker

Most patients with a cardiac resynchronisation therapy (CRT) pacemaker would not benefit from the addition of a defibrillator, according to results from the CeRtiTuDe cohort study presented for the first time today at ESC Congress1 and published in European Heart Journal.

1 Sep 2015

SLU scientist receives grant to solve blood-clotting mysteries

Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a "linker" region that may be the key to developing better life-saving drugs.

1 Sep 2015

Treating cancer cells with quizartinib inhibits key metabolic pathway, activates macroautophagy

A study published in The Journal of Cell Biology describes a way to force cancer cells to destroy a key metabolic enzyme they need to survive.

1 Sep 2015

Study: Retrieval of larger thrombi during IAT linked to improved neurological recovery after acute ischaemic stroke

Retrieval of larger thrombi during intra arterial treatment (IAT) is associated with improved neurological recovery after acute ischaemic stroke, according to a sub study of the MR CLEAN trial presented at ESC Congress today by Dr Anouchska Autar, PhD candidate at the Erasmus Medical Centre in Rotterdam, the Netherlands.

1 Sep 2015

Preoperative statins linked to reductions in cardiac complications, mortality after noncardiac surgery

Preoperative statins are associated with a 17% reduction in cardiac complications and a 43% reduction in mortality after noncardiac surgery, according to results from the VISION Study presented for the first time today at ESC Congress by Dr Otavio Berwanger, director of the Research Institute HCor, Hospital do Coração (Heart Hospital) in São Paulo, Brazil.

1 Sep 2015

Study calls for new strategies to shape perceptions of patients at risk for falls in hospitals

Falls are the most common adverse event among hospitalized patients, and a study published in the September issue of the American Journal of Critical Care examines an often overlooked element to preventing falls in hospitals: patient perceptions of their personal risk.

1 Sep 2015

Lifestyle changes lead to sharp reduction in strenuousness of daily life

New research from Royal Holloway, University of London has found that changes in lifestyle over the past 30 years have led to a sharp reduction in the strenuousness of daily life, which researchers say may explain why there has been a dramatic rise in obesity.

1 Sep 2015

GARFIELD-AF Registry: All-cause death is most frequent major event in newly diagnosed AF patients

The first-ever two-year outcomes from the Global Anticoagulant Registry in the Field - Atrial Fibrillation (GARFIELD-AF) showcased at ESC Congress 2015 expose that all-cause death was the most frequent major event in more than 17,000 newly diagnosed AF patients, far exceeding the rate of stroke or major bleeding.

1 Sep 2015

Scientists closer to understanding how neurons are wired to form circuits in the eye

When we move our head, the whole visual world moves across our eyes. Yet we can still make out a bee buzzing by or a hawk flying overhead, thanks to unique cells in the eye called object motion sensors.

1 Sep 2015

Adequate intake of choline essential for good health and physical performance

Athletes and physically active people of all ages can benefit from choline not only for their overall health, but also because it supports muscle performance during exercise, and can improve stamina.

1 Sep 2015

Experts to discuss research on lupus at world congress organized by MedUni Vienna

Lupus is an autoimmune disease with so many different symptoms that it is often difficult to diagnose and to treat. Despite huge medical advances over the last few years, lupus is incurable. Modern, individually tailored therapeutic approaches are aimed at helping sufferers. The world congress organized by MedUni Vienna brings experts from more than 80 countries together in Vienna from 2 to 6 September to discuss the latest research results and therapies.

1 Sep 2015

Non-invasive FFRCT test can reduce need for invasive tests in patients having chest pain

According to results of the PLATFORM (Prospective LongitudinAl Trial of FFRCT: Outcome and Resource Impacts) trial, a test known as FFRCT can obviate the need for invasive tests in up to 61% of patients who have chest pain and suspected coronary artery disease.

1 Sep 2015

Temple-led study shows benefits of using digital health application for COPD patients

Early intervention facilitated by a digital health application for reporting symptoms of Chronic Obstructive Pulmonary Disease (COPD) provides key benefits for patients, according to the results of a Temple-led, two-year clinical study.

1 Sep 2015

Medical Research News

Familial hypercholesterolemia patients can benefit from alirocumab drug

Diagnosing traumatic brain injury through a blood test: an interview with Dr Korley

Administering ticagrelor in the ambulance cuts ischaemic events 24 hours following PCI

Men with relatively unaggressive prostate tumors unlikely to develop metastatic prostate cancer

North Shore-LIJ researcher compares safety benefits two blood-thinning medications

New statistical model may help predict patients most likely to benefits from surgical treatment for mesothelioma

Finerenone effective in heart failure patients with diabetes and/or chronic kidney disease

Defibrillator does not improve outcomes in patients with CRT pacemaker

SLU scientist receives grant to solve blood-clotting mysteries

Treating cancer cells with quizartinib inhibits key metabolic pathway, activates macroautophagy

Study: Retrieval of larger thrombi during IAT linked to improved neurological recovery after acute ischaemic stroke

Preoperative statins linked to reductions in cardiac complications, mortality after noncardiac surgery

Study calls for new strategies to shape perceptions of patients at risk for falls in hospitals

Lifestyle changes lead to sharp reduction in strenuousness of daily life

GARFIELD-AF Registry: All-cause death is most frequent major event in newly diagnosed AF patients

Scientists closer to understanding how neurons are wired to form circuits in the eye

Adequate intake of choline essential for good health and physical performance

Experts to discuss research on lupus at world congress organized by MedUni Vienna

Non-invasive FFRCT test can reduce need for invasive tests in patients having chest pain

Temple-led study shows benefits of using digital health application for COPD patients

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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