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Early promise for pulmonary artery denervation in PAH patients

Pulmonary artery denervation is feasible and may reduce pulmonary arterial pressure in patients with pulmonary arterial hypertension, phase II findings suggest.

11 Dec 2015

Post-progression afatinib exposure boosts NSCLC outcomes

Continued exposure to afatinib plus paclitaxel can benefit non-small-cell lung cancer patients who developed resistance to erlotinib or gefitinib and progressed after initially responding to afatinib monotherapy, suggest phase III trial results.

11 Dec 2015

Right atrial function could be prognostic in PAH

Right atrial function is impaired in patients with pulmonary arterial hypertension and may indicate right ventricular overload and failure, research suggests.

11 Dec 2015

$Role for carfilzomib in relapsed, refractory multiple myeloma treatment$

Role for carfilzomib in relapsed, refractory multiple myeloma treatment

Carfilzomib significantly improves outcomes in previously treated patients with relapsed or refractory multiple myeloma, shows a head-to-head comparison with bortezomib.

11 Dec 2015

Slow walking speed may herald Alzheimer’s disease

A slow walking speed in elderly people is associated with the presence of β-amyloid in their brains, research shows.

11 Dec 2015

Androgen deprivation therapy elevates Alzheimer’s risk

US researchers find that androgen deprivation therapy increases the risk of Alzheimer’s disease in men with prostate cancer, with the risk rising with greater duration of therapy.

11 Dec 2015

Mount Sinai scientists develop new tool to determine global role of microRNAs

As microRNA biology has been implicated in everything from the development of cancer to virus infections, a new tool developed by scientists at the Icahn School of Medicine at Mount Sinai holds tremendous potential to develop new therapies that involve these small regulatory fragments of RNA.

11 Dec 2015

ER stroke cases have some degree of preventability, UCI study shows

Many strokes that required immediate treatment in emergency rooms may have been preventable, according to a University of California, Irvine study.

11 Dec 2015

Benefits of early dementia diagnosis may lead to challenging issues, new study shows

A new epidemiologic study showed that patients with early stage dementia, who had been referred to a specialist, have twice the risk of institutionalization compared to those who are not, according to a research study published in the Journal of Alzheimer's Disease this month.

11 Dec 2015

Cheerleading injuries are few, but often serious

Colorado School of Public Health experts revealed yesterday that cheerleading is one of the safest high school sports, according to an analysis of school sports-related injuries.

11 Dec 2015

Researchers find new method to create uniform standards in search for cancer-relevant mutations

Oncologists are increasingly using information obtained from investigations of the tumor genome in order to find individualized therapies for patients. They specifically search the hereditary information of cancer cells for mutations that drive malignant growth. By now, targeted drugs against many of these cancer-typical cellular alterations have become available.

11 Dec 2015

Findings may lead to new treatment strategy for phobia

A new study published in the latest issue of Biological Psychiatry reports the successful and instant reduction of fear in spider-fearful participants following a 2-minute exposure combined with a single dose of a regular pharmacological treatment.

11 Dec 2015

UC San Diego biologists develop a method to screen natural products for new antibiotics

Biologists at UC San Diego have found that a method they developed to identify and characterize new antibiotics can be employed to screen natural products quickly for compounds capable of controlling antibiotic resistant bacteria.

11 Dec 2015

Negative views of aging affect memory and hearing abilities in older adults

A study led by researchers at the University of Toronto shows that when older adults feel negatively about aging, they may lack confidence in their abilities to hear and remember things, and perform poorly at both.

11 Dec 2015

Early life exposures to toxic chemicals reduce infants' response to TB vaccine

Early life exposures to toxic chemicals such as PCBs and DDT dampen an infant's response to the tuberculosis vaccine, according to a new study from the University of Rochester Environmental Health Sciences Center.

11 Dec 2015

Emissions controls making a difference in reducing exposure to mercury

Emissions controls on coal-fired power plants are making a difference in reducing exposure of mercury to people, especially in the western Maryland community. A study of air quality from the University of Maryland Center for Environmental Science found that levels of mercury in the air from power plant emissions dropped more than half over a 10-year period, coinciding with stricter pollution controls.

11 Dec 2015

Advanced thyroid cancer rates above national average in several parts of California

A team of UCLA researchers found that there are several parts of California where, in a high percentage of people with thyroid cancer, the disease is already at an advanced stage by the time it is diagnosed.

11 Dec 2015

Employers pay billions of dollars for health care tied to unhealthy lifestyle choices

One out of every four dollars employers pay for health care is tied to unhealthy lifestyle choices or conditions like smoking, stress and obesity, despite the fact that most large employers have workplace wellness programs.

11 Dec 2015

Discovery may provide reliable 'clock' for forensic scientists

Researchers at University of California, San Diego School of Medicine and University of Colorado Boulder have discovered that unique and changing microbial communities present during decomposition of human cadavers may provide a reliable "clock" for forensic scientists. The method could be used to estimate time of death in different seasons, as well determine the original location of moved corpses and help locate buried corpses.

11 Dec 2015

Study reveals why anti-hormone therapy tamoxifen works better in some women than others

The anti-hormone therapy tamoxifen can reduce breast cancer recurrence by about half in women with hormone-sensitive breast cancer. But it works better in some women than others. Researchers are not sure why.

11 Dec 2015